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Brief Title: Systemic Therapy With or Without Upfront Transarterial Embolization for Inoperable Liver Metastasis of Neuroendocrine Tumors
Official Title: Randomized Phase 3 Trial Evaluating the Efficacy of Locoregional Treatment With Transarterial Embolization (TAE) for Liver Metastases, in Combination With Pharmacotherapy, in Patients With Neuroendocrine Tumor and Inoperable Liver Metastasis.
Study ID: NCT01755182
Brief Summary: The purpose of this study is to verify if adding a locoregional treatment of liver metastasis (with trans-arterial embolization-TAE) to medical treatments of proven efficacy can prolong the progression free survival of patients affected by neuroendocrine tumors (NET) with inoperable liver metastases
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Albano Laziale Ospedale "Regina Apoltolorum", Albano Laziale, , Italy
Università di Ferrara, Ferrara, , Italy
Università di Genova, Genova, , Italy
Istituto Europeo di Oncologia, Milano, , Italy
Istituto Nazionale Tumori, Milano, , Italy
Ospedale San Raffaele, MIlano, , Italy
Istituto Nazionale dei Tumori, Napoli, , Italy
Ospedale Cardarelli, Napoli, , Italy
Presidio Monaldi - AORN Ospedale dei Colli, Napoli, , Italy
Istituto Regina Elena, Roma, , Italy
Azienda Ospedaliero-Universitaria S.M. della Misericordia di Udine, Udine, , Italy
Università di Verona Policlinico GB Rossi, Verona, , Italy
Name: A Colao, M.D.
Affiliation: Federico II University
Role: PRINCIPAL_INVESTIGATOR
Name: A Faggiano, M.D.
Affiliation: Federico II University
Role: PRINCIPAL_INVESTIGATOR
Name: R D'Angelo, M.D.
Affiliation: NCI Naples
Role: PRINCIPAL_INVESTIGATOR
Name: F Fiore, MD
Affiliation: NCI Naples
Role: PRINCIPAL_INVESTIGATOR
Name: F Perrone, MD
Affiliation: NCI Naples
Role: PRINCIPAL_INVESTIGATOR
Name: C Gallo, MD
Affiliation: University of Campania "Luigi Vanvitelli"
Role: PRINCIPAL_INVESTIGATOR
Name: MC Piccirillo, MD
Affiliation: NCI Naples
Role: PRINCIPAL_INVESTIGATOR