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Brief Title: Everolimus After (Chemo)Embolization for Liver Metastases From Digestive Endocrine Tumors
Official Title: Everolimus as Treatment After Embolization or Chemoembolization for Liver Metastases From Digestive Endocrine Tumors
Study ID: NCT01678664
Brief Summary: Determine wether 24 months treatment with everolimus prolongs progression free survival rate (based on a central assessment) after embolisation ou chemoembolisation for liver metastases. * H0 a 24 months progression free survival rate less than 35% is unacceptable * H1 a 24 months progression free survival rate greater than 35% would show that everolimus treatment is beneficial, the expected 24 months progression free survival rate being 50%
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
CHU - Hôtel Dieu, Angers, , France
Hôpital Avicenne, Bobigny, , France
Hôpital Saint André, Bordeaux, , France
Hôpital Côte de Nacre, Caen, , France
CHU - Estaing, Clermont Ferrand, , France
Hôpital Beaujon, Clichy, , France
Centre GF Leclerc, Dijon, , France
CHU - Hôpital François Mitterand, Dijon, , France
Hôpital Edouard Herriot, Lyon, , France
CHU La Timone, Marseille, , France
CHR, Orléans, , France
CHU Cochin, Paris, , France
Hôpital Européen Georges Pompidou, Paris, , France
Hôpital Robert Debré, Reims, , France
CHU, Rouen, , France
Hôpital Rangueil, Toulouse, , France
Hôpital Trousseau, Tours, , France
Institut Gustave Roussy, Villejuif, , France
Name: Thomas WALTER, PhD
Affiliation: Hôpital Edouard Herriot - Lyon
Role: PRINCIPAL_INVESTIGATOR