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Brief Title: A Trial of Cabozantinib in Patients With Advanced, Low Proliferative NEN G3
Official Title: CABONEN - A Phase II Trial of Cabozantinib in Patients With Advanced, Low Proliferative NEN G3
Study ID: NCT04524208
Brief Summary: The main objective of this clinical trial represents the evaluation of efficacy of the tyrosine kinase inhibitor Cabozantinib in patients with NEN G3 with a proliferation rate of Ki67 20 - 60%.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Medizinische Universität Wien, Wien, , Austria
University Medical Center Göttingen, Göttingen, Lower Saxony, Germany
Zentralklinik Bad Berka GmbH, Bad Berka, , Germany
Universitätsklinikum Carl Gustav Carus, Dresden, , Germany
Universitätsklinikum Erlangen, Erlangen, , Germany
Universitätsklinikum Freiburg, Freiburg, , Germany
Universitätsklinikum Halle, Halle, , Germany
Asklepios St. Georg, Hamburg, , Germany
Medizinische Hochschule Hannover, Hannover, , Germany
Klinikum Heidelberg, Heidelberg, , Germany
Universitätsmedizin Mannheim, Mannheim, , Germany
Universitätsklinikum Gießen und Marburg GmbH, Marburg, , Germany
Johannes-Wesling-Klinikum Minden, Minden, , Germany
Klinikum Ulm, Ulm, , Germany
Universitätsklinik Würzburg, Würzburg, , Germany
Name: Alexander König, PD Dr.
Affiliation: University Medical Center Göttingen
Role: PRINCIPAL_INVESTIGATOR