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Brief Title: Systemic Targeted Adaptive RadioTherapy of NeuroEndocrine Tumors.
Official Title: Systemic Targeted Adaptive RadioTherapy of NeuroEndocrine Tumors. An Open-label, Multicenter, Randomized Phase III Trial Comparing Safety and Efficacy of Personalized Versus Non-personalized Radionuclide Therapy With 177Lu (Lutetium)-DOTATOC.
Study ID: NCT05387603
Brief Summary: There are several ways of personalizing PRRT (peptide receptor radionuclide treatment) in NEN (neuroendocrine neoplasia). Nevertheless, the current treatment regimen is not personalized. This trial aims to compare personalized PRRT to non-personalized PRRT in terms of safety, efficacy and resource demands in order to optimize treatment outcomes in an evidence-based manner in future.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Sahlgrenska University Hospital, Dept. of Oncology, Göteborg, , Sweden
Skåne University Hospital, Dept. of Oncology, Lund, , Sweden
Karolinska University Hospital, Dept. of Oncology, Stockholm, , Sweden
Accademical Hospital, Uppsala, Dept. of Oncology, Uppsala, , Sweden