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Spots Global Cancer Trial Database for Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma

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Trial Identification

Brief Title: Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma

Official Title: An Open-label, Phase 1b/2 Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma

Study ID: NCT02180711

Study Description

Brief Summary: Part 1: To characterize the safety profile of acalabrutinib alone or in combination with rituximab in subjects with R/R FL. Part 2: To characterize the activity of acalabrutinib alone or in combination with rituximab in subjects with R/R MZL, as measured by ORR. Part 3: To characterize the safety of acalabrutinib in combination with rituximab and lenalidomide in subjects with R/R FL

Detailed Description: An Open-label, Phase 1b/2 Study of Acalabrutinib Alone or in Combination Therapy in Subjects with B-cell Non-Hodgkin Lymphoma

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Research Site, Tucson, Arizona, United States

Research Site, Downey, California, United States

Research Site, Duarte, California, United States

Research Site, Fountain Valley, California, United States

Research Site, Santa Monica, California, United States

Research Site, Coral Gables FL, Florida, United States

Research Site, Chicago, Illinois, United States

Research Site, Chicago, Illinois, United States

Research Site, Chicago, Illinois, United States

Research Site, Louisville, Kentucky, United States

Research Site, New Orleans, Louisiana, United States

Research Site, Ann Arbor, Michigan, United States

Research Site, Morristown, New Jersey, United States

Research Site, Hawthorne, New York, United States

Research Site, Lake Success, New York, United States

Research Site, New York, New York, United States

Research Site, Syracuse, New York, United States

Research Site, Columbus, Ohio, United States

Research Site, Greenville, South Carolina, United States

Research Site, Dallas, Texas, United States

Research Site, Houston, Texas, United States

Research Site, San Antonio, Texas, United States

Research Site, Temple, Texas, United States

Research Site, Salt Lake City, Utah, United States

Research Site, Spokane, Washington, United States

Research Site, Waukesha, Wisconsin, United States

Research Site, Edmonton, Alberta, Canada

Research Site, London, Ontario, Canada

Research Site, Toronto, Ontario, Canada

Research Site, Bologna, , Italy

Research Site, Milano, , Italy

Research Site, Palermo, , Italy

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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