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Brief Title: Obinutuzumab and ICE Chemotherapy in Refractory/Recurrent CD20+ Mature NHL
Official Title: Chemoimmunotherapy With Obinutuzumab, Ifosfamide, Carboplatin and Etoposide (O-ICE) in Children, Adolescents and Young Adults With Recurrent Refractory CD20+ Mature B-NHL
Study ID: NCT02393157
Brief Summary: The purpose of this study is to determine the safety of administering obinutuzumab as a single agent alone and in combination with ifosfamide, carboplatin, and etoposide (ICE) chemotherapy and determine the response rate of this treatment for children, adolescents and young adults (CAYA) with relapsed CD20 positive B-cell Non-Hodgkin Lymphoma (B-NHL).
Detailed Description:
Minimum Age: 3 Years
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
New York Medical College, Valhalla, New York, United States
Name: Mitchell Cairo, MD
Affiliation: New York Medical College
Role: STUDY_CHAIR
Name: Matthew Barth, MD
Affiliation: Roswell Park Cancer Institute
Role: PRINCIPAL_INVESTIGATOR