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Brief Title: Prospective Multicenter Dose Finding Phase II Pilot Trial to Evaluate Efficacy and Safety of LR-CHOP21 for Elderly Patients With Untreated Diffuse Large B Cell Lymphoma
Official Title: Prospective Multicenter Dose Finding Phase II Pilot Trial to Evaluate Efficacy and Safety of Treatment With Lenalidomide Plus R-CHOP21 (LR-CHOP21) for Elderly Patients With Untreated Diffuse Large B Cell Lymphoma (DLBCL)
Study ID: NCT00907348
Brief Summary: This is a prospective multicenter phase II pilot trial designed with the purpose of dose finding to evaluate the efficacy and safety of treatment with Lenalidomide plus R-CHOP21 (LR-CHOP21) for elderly patients with untreated Diffuse Large B Cell Lymphoma (DLBCL).
Detailed Description:
Minimum Age: 60 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Divisione di Ematologia Osp. SS. Antonio e Biagio, Alessandria, , Italy
Divisione di Oncologia Medica A Centro di Riferimento Oncologico, Aviano, , Italy
Cattedra di Ematologia Università Policlinico, Bari, , Italy
IRCCS Istituto Tumori Giovanni Paolo II, Bari, , Italy
Istituto di Ematologia "Seragnoli" Polic.S.Orsola-Malpighi, Bologna, , Italy
Divisione di Ematologia Spedali Civili, Brescia, , Italy
Divisione di Ematologia Osp. Businco, Cagliari, , Italy
Onco-Ematologia I.R.C.C., Candiolo (TO), , Italy
Ematologia 1 Ospedale S. Martino, Genova, , Italy
Divisione di Ematologia Ospedale Niguarda, Milano, , Italy
UO Ematologia II Facoltà di Medicina e Chirurgia Università Federico II, Napoli, , Italy
Divisione di Ematologia Università Avogadro, Novara, , Italy
UO Ematologia Università - Policlinico San Matteo, Pavia, , Italy
Dipartimento di biotecnologie cellulari ed ematologia Ospedale Umberto I - La Sapienza, Roma, , Italy
Oncoematologia - Univ. Perugia Sede Terni,, Terni, , Italy
S.C.Ematologia 1 AOU San Giovanni Battista, Torino, , Italy
SC Ematologia 2 ASO San Giovanni Battista, Torino, , Italy
UO Ematologia Osp. Cardinale Panico, Tricase (LE), , Italy
Name: Umberto Vitolo, MD
Affiliation: Azienda Sanitaria Ospedaliera-Universitaria S. Giovanni Battista - TORINO
Role: STUDY_DIRECTOR