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Brief Title: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies
Official Title: An Open-Label, Multicenter, Phase II Trial Evaluating the Safety, Efficacy, and Pharmacokinetics of Subcutaneous Mosunetuzumab Monotherapy in Patients With Select B-Cell Malignancies
Study ID: NCT05207670
Brief Summary: This study will evaluate the efficacy, safety, and pharmacokinetics of mosunetuzumab subcutaneous (SC) formulation in participants with selected B-cell malignancies (types of non-Hodgkin's lymphoma \[NHL\]).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Infirmary Cancer Care, Mobile, Alabama, United States
Alaska Oncology & Hematology, LLC, Anchorage, Alaska, United States
Mayo Clinic Arizona, Phoenix, Arizona, United States
City of Hope, Duarte, California, United States
Marin Cancer Care Inc, Greenbrae, California, United States
Marin General Hospital, Greenbrae, California, United States
Rocky Mountain Cancer Centers (Aurora) - USOR, Aurora, Colorado, United States
Medical Oncology Hematology Consultants, Newark, Delaware, United States
SCRI Florida Cancer Specialists South, Fort Myers, Florida, United States
Mayo Clinic Jacksonville - PPDS, Jacksonville, Florida, United States
Cancer Specialists of North Florida (AC Skinner Bldg 100), Jacksonville, Florida, United States
Florida Cancer Specialists - NORTH - SCRI - PPDS, Saint Petersburg, Florida, United States
Florida Cancer Specialists - EAST - SCRI - PPDS, West Palm Beach, Florida, United States
St Luke?s Cancer Institute, Boise, Idaho, United States
Mission Blood and Cancer - MercyOne Cancer Center, Des Moines, Iowa, United States
University of Kansas Medical Center, Westwood, Kansas, United States
Hematology Oncology Clinic, Baton Rouge, Louisiana, United States
American Oncology Partners of Maryland, PA, Bethesda, Maryland, United States
Ascension Health Van Elsander Cancer Center, Grosse Pointe Woods, Michigan, United States
Mayo Clinic - PPDS, Rochester, Minnesota, United States
St. Vincent Frontier Cancer Center, Billings, Montana, United States
Benefis Hospital Sletten Cancer Institute, Great Falls, Montana, United States
Astera Cancer Care East Brunswick, East Brunswick, New Jersey, United States
Englewood Hospital and Medical Center, Englewood, New Jersey, United States
Summit Medical Group; MD Anderson Cancer Center, Florham Park, New Jersey, United States
Atlantic Hematology Oncology, Morristown, New Jersey, United States
Overlook Medical Center, Summit, New Jersey, United States
San Juan Oncology Associates, Farmington, New Mexico, United States
New York Oncology Hematology, P.C., Albany, New York, United States
New York Cancer & Blood Specialists - Bronx, Bronx, New York, United States
New York Cancer & Blood Specialists - New Hyde Park, New Hyde Park, New York, United States
NY Cancer & Blood Specialist, New York, New York, United States
North Shore Hematology Oncology Association PC, Shirley, New York, United States
Oncology Hematology Care Inc - Cincinnati - USOR, Cincinnati, Ohio, United States
Hightower Clinical, Oklahoma City, Oklahoma, United States
Asante Spears Cancer Center, Grants Pass, Oregon, United States
Asante Heimann Cancer Center - Medford, Medford, Oregon, United States
Asante Rogue Regional Medical Center, Medford, Oregon, United States
Kaiser Foundation Hospitals, Portland, Oregon, United States
Providence Cancer Center, Portland, Oregon, United States
Oncology Associates of Oregon, P.C.; Willamette Valley Cancer Institute, Springfield, Oregon, United States
Lancaster General Hospital, Lancaster, Pennsylvania, United States
McGlinn Cancer Institute at Reading Hospital, West Reading, Pennsylvania, United States
Prisma Health Cancer Institute; Research Pharmacy, Greenville, South Carolina, United States
Tennessee Oncology Chattanooga, Chattanooga, Tennessee, United States
Tennessee Oncology - Nashville, Franklin, Tennessee, United States
Texas Oncology (Amarillo) - USOR - 1826 Point West Pkwy, Amarillo, Texas, United States
Texas Oncology-Austin Midtown, Austin, Texas, United States
Texas Oncology (Worth) - USOR, Dallas, Texas, United States
Texas Oncology (Tyler) - USOR, Tyler, Texas, United States
Virginia Cancer Specialists - Gainsville, Gainesville, Virginia, United States
Kadlec Clinic Hematology and Oncology, Kennewick, Washington, United States
Swedish Medical Center, Seattle, Washington, United States
VA Puget Sound Health Care System - NAVREF - PPDS, Seattle, Washington, United States
Cancer Care Northwest, Spokane, Washington, United States
MultiCare Deaconess Cancer and Blood Specialty Center, Spokane, Washington, United States
Northwest Medical Specialties, Tacoma, Washington, United States
Auxilio Mutuo Cancer Center, San Juan, , Puerto Rico
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR