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Brief Title: Biological Response to Tamoxifen (TAM) in Patients With Breast Cancer Non Metastatic RH+
Official Title: Phase II Study Evaluating According to the Polymorphism of CYP2D6, the Rate of Biological Response to Treatment With Tamoxifen (TAM) Administered in Pre-operative Situation in Patients With Breast Cancer Non Metastatic HR+
Study ID: NCT01220076
Brief Summary: The biological response to treatment with tamoxifen in the preoperative situation is studying in this protocol. This study will enrolls patients with non-metastatic breast cancer HR +. The relationship between the CYP2D6 polymorphism, pharmacokinetics and biological efficacy of TAM will be studied.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Centre Léon Berard, Lyon, , France
Institut Curie, Paris, , France
Institut de Cancerologie de l'Ouest (ICO), Saint Herblain, , France