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Brief Title: A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy
Official Title: A Phase III, Randomized, Double-blind Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Stage IIB, IIIA, or Select IIIB, PD-L1 Positive, Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy
Study ID: NCT06267001
Brief Summary: The purpose of this study is to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo plus atezolizumab administered to participants with non-small cell lung cancer (NSCLC) following resection and adjuvant chemotherapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The Oncology Institute of Hope and Innovation; Cerritos, Cerritos, California, United States
University of California, San Francisco; Medical Center, San Francisco, California, United States
The Oncology Institute of Hope and Innovation - Florida, Fort Lauderdale, Florida, United States
James A. Haley Veterans Hospital, Tampa, Florida, United States
Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital, Marietta, Georgia, United States
Springfield Clinic, Springfield, Illinois, United States
UNM Lovelace, Albuquerque, New Mexico, United States
University of New Mexico Cancer Center, Albuquerque, New Mexico, United States
Asante Rogue Regional Medical Center, Medford, Oregon, United States
Baptist Cancer Center, Memphis, Tennessee, United States
Hospital Britanico; Oncologia, Buenos Aires, , Argentina
Centro Oncologico Korben; Oncology, Ciudad Autonoma Buenos Aires, , Argentina
CINME S.A. ? Centro de Investigaciones Metabolicas - Rx Trials LLC, Ciudad Autonoma de Buenos Aires, , Argentina
Sanatorio Parque S.A., Rosario, , Argentina
Sunshine Coast University Hospital; The Adem Crosby Centre, Birtinya, Queensland, Australia
Greenslopes Private Hospital; Gallipoli Research Centre, Greenslopes, Queensland, Australia
Cancer Research SA, Adelaide, South Australia, Australia
Monash Health, Clayton, Victoria, Australia
Crio - Centro Regional Integrado de Oncologia, Fortaleza, CE, Brazil
Hospital da Cidade de Passo Fundo; Centro de Pesquisa em Oncologia, Passo Fundo, RS, Brazil
Hospital de Cancer de Barretos, Barretos, SP, Brazil
Hospital A. C. Camargo; Oncologia, Sao Paulo, SP, Brazil
Changzhou First People's Hospital; Oncology, Changzhou, , China
The First Affiliated Hospital of Sun Yat-sen University, Guangzhou City, , China
Guangdong General Hospital, Guangzhou, , China
Shandong Cancer Hospital, Jinan, , China
Yunnan Cancer Hospital, Kunming, , China
The First Affiliated Hospital of Nanchang University, Nanchang City, , China
Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing City, , China
Ningbo No.2 Hospital, Ningbo, , China
The Affiliated Hospital Of Qingdao University, Qingdao, , China
Zhongshan Hospital Fudan University, Shanghai, , China
Shanghai Pulmonary Hospital, Shanghai, , China
Liaoning Provincial Cancer Hospital, Shengyang, , China
Tianjin Cancer Hospital, Tianjin, , China
Tongji Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan City, , China
The Affiliated Hospital of Xuzhou Medical University, Xuzhou, , China
Zhejiang Cancer Hospital, Zhejiang, , China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, , China
Queen Mary Hospital; Centre of Cancer Medicine, Hong Kong, , Hong Kong
Hiroshima University Hospital, Hiroshima, , Japan
Kindai University Hospital, Osaka, , Japan
The Cancer Institute Hospital of JFCR, Tokyo, , Japan
Pusan National University Hospital, Busan, , Korea, Republic of
Chungbuk National University Hospital, Cheongju si, , Korea, Republic of
Kyungpook National University Chilgok Hospital, Daegu, , Korea, Republic of
St. Vincent's Hospital, Gyeonggi-do, , Korea, Republic of
Pusan National University Yangsan Hospital, Gyeongsangnam-do, , Korea, Republic of
Chonnam National University Hwasun Hospital, Jeollanam-do, , Korea, Republic of
Seoul National University Bundang Hospital, Seongnam-si, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Korea University Guro Hospital, Seoul, , Korea, Republic of
Ulsan University Hosiptal, Ulsan, , Korea, Republic of
Kaohsiung Medical Uni Chung-Ho Memorial Hospital; Dept of Internal Medicine, Kaohsiung, , Taiwan
E-DA Hospital; Chest, Kaohsiung, , Taiwan
Taichung Veterans General Hospital; Dept of Internal Medicine, Taichung, , Taiwan
Taipei Veterans General Hospital; Chest Dept , Section of Thoracic Oncology, Taipei, , Taiwan
Tri-Service General Hospital; Dept. of Internal Medicine, Taipei, , Taiwan
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR