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Brief Title: MILES-3: Cisplatin in Combination With Gemcitabine for Elderly Patients With Lung Cancer
Official Title: Randomized Phase III Study of the Addition of Cisplatin in Combination With Gemcitabine as First-line Therapy for Elderly Patients With Advanced Non Small Cell Lung Cancer.
Study ID: NCT01405586
Brief Summary: The purpose of this study is to evaluate the addition of cisplatin to first-line chemotherapy with gemcitabine in elderly patients with non small cell lung cancer in terms of overall survival.
Detailed Description:
Minimum Age: 70 Years
Eligible Ages: OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Ospedale Villa Scassi, Genova, GE, Italy
Policlinico Giaccone, Palermo, PA, Italy
Azienda Ospedaliera Universitaria Senese, Siena, SI, Italy
Ospedale Regina Apostolorum, Albano Laziale, , Italy
Ospedale San Lazzaro, Alba, , Italy
AOU Ospedale Riuniti Umberto I, Ancona, , Italy
ASL Latina Distretto 1 Aprilia Univ.degli Studi di Roma, Aprilia, , Italy
Ospedale Cardinale Massaia, Asti, , Italy
S. Giuseppe Moscati, Avellino, , Italy
Centro Riferimento Oncologico, Aviano, , Italy
Ospedale Senatore Antonio Perrino, Brindisi, , Italy
Ospedale A. Cardarelli, Campobasso, , Italy
Ospedale Ramazzini di Carpi, Carpi, , Italy
Ospedale S. Spirito, Casale Monferrato, , Italy
A.O. Garibaldi Nesima, Catania, , Italy
Ospedale Mater Domini, Catanzaro, , Italy
Ospedale della Madonna della Navicella, Chioggia, , Italy
Ospedale Civile di Faenza, Faenza, , Italy
A.O.U. Arcispedale Sant'Anna di Ferrara, Ferrara, , Italy
Ospedale Don Luigi Di Liegro, Gaeta, , Italy
IRCCS San Martino -IST Genova, Genova, , Italy
Ospedale F. Veneziale, Isernia, , Italy
A.O. Vito Fazzi-Lorusso, Lecce, , Italy
Ospedale Civile di Legnano, Legnano, , Italy
Istituto Sceintifico Romagnolo, Meldola, , Italy
Ospedale L. Sacco Polo Universitario, Milano, , Italy
Ospedale San Paolo, Milano, , Italy
U.L.S.S. 13, Mirano, , Italy
Ospedale San Gerardo, Monza, , Italy
Azienda Ospedaliera Cardarelli, Napoli, , Italy
Second University of Naples, Napoli, , Italy
A.O. Università Federico II, Napoli, , Italy
AORN Ospedale dei Colli - Osp Monaldi, Napoli, , Italy
Istituto Nazionale dei Tumori, Napoli, , Italy
Istituto Oncologico Veneto, Padova, , Italy
Ospedale Andrea Tortora Pagani - Ospedale Civile Umbero I, Pagani, , Italy
Casa di Cura La Maddalena, Palermo, , Italy
Ospedale Buccheri La Ferla - Fatebenefratelli, Palermo, , Italy
Fondazione Salvatore Maugeri, Pavia, , Italy
Ospedale Guglielmo d Saliceto-Piacenza, Piacenza, , Italy
Azienda Ospedaliera S. Carlo, Potenza, , Italy
Ospedale S. Maria delle Croci, Ravenna, , Italy
Ospedale Umberto I, Ravenna, , Italy
A.O. S. Camillo Forlanini, Roma, , Italy
Campus Biomedico Policlinio Universitario, Roma, , Italy
Ospedale S. Giovanni Calibita Fatebenefratelli, Roma, , Italy
Ospedale S. Andrea, Vercelli, , Italy
Ospedale S. Bortolo ULSS 6, Vicenza, , Italy
ASL Viterbo - Ospedale Belcolle, Viterbo, , Italy
Name: Cesare Gridelli, M.D.
Affiliation: S.G. Moscati Hopital, Avellino, Italy, Division of Medical Oncology
Role: PRINCIPAL_INVESTIGATOR
Name: Francesco Perrone, M.D., Ph.D
Affiliation: National Cancer Institute Naples, Italy; Director Clinical Trials Unit
Role: PRINCIPAL_INVESTIGATOR
Name: Ciro Gallo, M.D., Ph.D
Affiliation: Second University of Naples, Italy; Chair of Medical Statistics
Role: PRINCIPAL_INVESTIGATOR