Spots Global Cancer Trial Database for Efficacy of Treatment Sequences in Patients With Non-small Cell Lung Cancer Receiving Lorlatinib
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Trial Identification
Brief Title: Efficacy of Treatment Sequences in Patients With Non-small Cell Lung Cancer Receiving Lorlatinib
Official Title: Efficacy of Treatment Sequences in Patients With ALK and ROS-1 Positive Non-small Cell Lung Cancer Who Received Lorlatinib as Part of the French Expanded Access Program
Study ID: NCT03727477
Interventions
Study Description
Brief Summary: The study will evaluate progression-free survival, overall survival, best response and duration of treatment in patients with advanced ALK- and ROS1-positive non-small cell lung cancer who received lorlatinib as part of the French expanded access program.
Detailed Description: IFCT-1803 LORLATU study will evaluate progression-free survival, overall survival, best response and duration of treatment in patients with advanced ALK- and ROS1-positive non-small cell lung cancer who received lorlatinib (PF-06463922) as part of the French expanded access program. Those outcomes will be correlated to clinical, pathological, and radiological characteristics of patients.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Aix-en-Provence - CH, Aix-en-Provence, , France
Angers - CHU, Angers, , France
Annemasse - CH, Annemasse, , France
Avignon - CH, Avignon, , France
Bordeaux - Polyclinique, Bordeaux, , France
Brest - Morvan CHU, Brest, , France
Cahors - CH, Cahors, , France
Chartres-CH, Chartres, , France
Clermont-Ferrand - CHU, Clermont-Ferrand, , France
Colmar - CH, Colmar, , France
Créteil - CHI, Créteil, , France
La Roche-Sur-Yon - CH, La Roche-sur-Yon, , France
Libourne - CH, Libourne, , France
Lorient - CHBS, Lorient, , France
Lyon - CRLCC, Lyon, , France
Marseille - CRLCC, Marseille, , France
Montpellier - ICM, Montpellier, , France
Mulhouse - GHRMSA, Mulhouse, , France
Paris - Curie, Paris, , France
Paris - Saint-Louis, Paris, , France
Paris - Tenon, Paris, , France
Lyon - URCOT, Pierre-Bénite, , France
Reims - CHU, Reims, , France
Saint-Nazaire - Clinique Mutualiste de l'Estuaire, Saint-Nazaire, , France
Saint-Etienne - CHU, Saint-Étienne, , France
Toulouse - CHU, Toulouse, , France
Tours - CHU, Tours, , France
Valenciennes - Clinique, Valenciennes, , France
Vandoeuvre-lès-Nancy - CRLCC, Vandoeuvre-lès-Nancy, , France
Villejuif - Gustave Roussy, Villejuif, , France
Contact Details
Name: Nicolas Girard, MD, PhD
Affiliation: Institut Curie Paris
Role: PRINCIPAL_INVESTIGATOR
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