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Brief Title: NM404 as an Imaging Agent in Patients With NSCLC
Official Title: NM404 as an Imaging Agent in Patients With Non-small Cell Lung Cancer (NSCLC)
Study ID: NCT00582283
Brief Summary: This study seeks to determine imaging characteristics of radiolabelled 131-I-NM404 in ten patients with cancer, including calculations of PKs, radiation dosimetry, biodistribution, and optimal imaging times (part 1 - complete). In addition, specific tumor accumulation and metabolic fate of 131-I-NM404 will be determined in NSCLC tumors collected in 5 patients (part 2 - complete). Lastly, the study will collect preliminary data on imaging NSCLC tumors in up to 12 patients with evaluable disease (part 3 - ongoing).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Wisconsin Carbone Comprehensive Cancer Center, Madison, Wisconsin, United States
Name: Anne M Traynor, MD
Affiliation: University of Wisconsin, Madison
Role: PRINCIPAL_INVESTIGATOR