Spots Global Cancer Trial Database for A Study Comparing Bevacizumab Therapy With or Without Erlotinib for First-Line Treatment of Non-Small Cell Lung Cancer (ATLAS)
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Trial Identification
Brief Title: A Study Comparing Bevacizumab Therapy With or Without Erlotinib for First-Line Treatment of Non-Small Cell Lung Cancer (ATLAS)
Official Title: A Randomized, Double-Blind, Placebo-Controlled, Phase IIIb Trial Comparing Bevacizumab Therapy With or Without Erlotinib After Completion of Chemotherapy With Bevacizumab for the First-Line Treatment of Locally Advanced, Recurrent, or Metastatic Non-Small Cell Lung Cancer
Study ID: NCT00257608
Conditions
Study Description
Brief Summary: This is a Phase IIIb, multicenter, randomized, placebo-controlled trial to evaluate the safety and efficacy of chemotherapy+bevacizumab followed by bevacizumab+erlotinib versus bevacizumab+erlotinib placebo in subjects with locally advanced or metastatic NSCLC.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Sacred Heart Medical Onc Group, Mobile, Alabama, United States
St. Edward Mercy Medical Ctr, Ft Smith, Arizona, United States
Mayo Clinic, Scottsdale, Arizona, United States
Arizona Cancer Center, Tucson, Arizona, United States
Central Hem/Onc Medical Group, Alhambra, California, United States
Comp Blood & Cancer Center, Bakersfield, California, United States
South Bay Oncology, Campbell, California, United States
Bay Area Cancer Research Grp, Concord, California, United States
Pacific Onc & Hem Assoc, Encinitas, California, United States
Pacific Coast Hem/Onc, Fountain Valley, California, United States
Cancer Care Associates, Fresno, California, United States
St. Jude Heritage Med Group, Fullerton, California, United States
Ronald H. Yanagihara, Gilroy, California, United States
Glendale Adventist Medical Ctr, Glendale, California, United States
Scipps Clinic, La Jolla, California, United States
Loma Linda Univ Medical Center, Loma Linda, California, United States
Pacific Shores Medical Group, Long Beach, California, United States
Kenmar Research Institute LLC, Los Angeles, California, United States
UCLA Medical Ctr, Los Angeles, California, United States
Sutter Gould Med Foundation, Modesto, California, United States
North Valley Hem Onc Med Grp, Northridge, California, United States
Hem Onc Med Grp Orange Cty, Orange, California, United States
Medical Oncology Care Assoc, Orange, California, United States
Ventura Co Hem-Onc Specialists, Oxnard, California, United States
Wilshire Oncology Medical Grp, Pomona, California, United States
Sutter Cancer Center, Sacramento, California, United States
Mercy General Hospital, Sacramento, California, United States
Los Palos Oncology & Hem, Salinas, California, United States
Kaiser Permanente, San Diego, California, United States
Naval Medical Center, San Diego, California, United States
Pacific Hematology Oncology, San Francisco, California, United States
Kaiser Permanente Santa Teresa, San Jose, California, United States
Sansum Medical Clinic, Inc., Santa Barbara, California, United States
Santa Barbara Hem Onc Med Grp, Santa Barbara, California, United States
Central Coast Medical Oncology, Santa Maria, California, United States
The Angeles Clinic, Santa Monica, California, United States
Redwood Regional Med Grp, Santa Rosa, California, United States
Cancer Care Associates, Torrance, California, United States
Mile High Oncology, Denver, Colorado, United States
Front Range Cancer Specialists, Fort Collins, Colorado, United States
Washington Onc Hem Center PC, Washington, District of Columbia, United States
Center for Hematology-Oncology, Boca Raton, Florida, United States
Halifax Medical Center, Daytona Beach, Florida, United States
Florida Wellcare Alliance, Inverness, Florida, United States
Baptist Cancer Institute, Jacksonville, Florida, United States
Jackson Memorial Hospital, Miami, Florida, United States
Mid-Florida Hem Oncology Ctr, Orange City, Florida, United States
Integrated Comm Onc Network, Orange Park, Florida, United States
Hematology Onc Treasure Coast, Port Saint Lucie, Florida, United States
Phoebe Putney Cancer Center, Albany, Georgia, United States
Northeast Georgia Cancer Care, Athens, Georgia, United States
Suburban Hem-Onc Associates, Lawrenceville, Georgia, United States
Northwest Georgia Onc Centers, Marietta, Georgia, United States
Chicagoland Hematology Onc, Arlington Heights, Illinois, United States
Weiss-Strauss Oncology Center, Chicago, Illinois, United States
LaGrange Oncology Associates, Geneva, Illinois, United States
La Grange Oncology Associates, Lagrange, Illinois, United States
Associates in Medical Oncology, Oak Lawn, Illinois, United States
Onc Hem Assoc of Central IL, Peoria, Illinois, United States
West Suburban Cancer Center, River Forest, Illinois, United States
OSF St. Anthony Med Ctr, Rockford, Illinois, United States
Community Hospital, Munster, Indiana, United States
Providence Medical Group, Terre Haute, Indiana, United States
Hematology Oncology Associates, Bettendorf, Iowa, United States
Siouxland Hem-Onc Assoc LLP, Sioux City, Iowa, United States
Covenant Clinic, Waterloo, Iowa, United States
Gajera & Patel, PLLC, Hopkinsville, Kentucky, United States
Kentuckiana Cancer Center, Louisville, Kentucky, United States
University of Louisville, Louisville, Kentucky, United States
Consultants in Blood Disorders, Louisville, Kentucky, United States
Owensboro Medical Health Sys, Owensboro, Kentucky, United States
Willis-Knighton Cancer Center, Shreveport, Louisiana, United States
H&J Weinberg Cancer Institute, Baltimore, Maryland, United States
Oncology Hematology Associates, Clinton, Maryland, United States
Maryland Oncology/Hema PA, Columbia, Maryland, United States
Frederick Memorial Hospital, Frederick, Maryland, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
Caritas St. Elizabeth Med Ctr, Boston, Massachusetts, United States
Lahey Clinic Med Ctr, Burlington, Massachusetts, United States
Metrowest Cancer Center, Framingham, Massachusetts, United States
Baystate Medical Center, Springfield, Massachusetts, United States
Spectrum Health, Grand Rapids, Michigan, United States
Kalamazoo Hem & Onc, Kalamazoo, Michigan, United States
Marquette General Health Sys, Marquette, Michigan, United States
St. Joseph Mercy Oakland, Pontiac, Michigan, United States
William Beaumont Hospital, Royal Oak, Michigan, United States
Virginia Piper Cancer Inst, Minneapolis, Minnesota, United States
Ellis Fischel Cancer Center, Columbia, Missouri, United States
Freeman Cancer Institute, Joplin, Missouri, United States
St. Louis Univ Care Center, Saint Louis, Missouri, United States
Missouri Cancer Center, PC, St Charles, Missouri, United States
Arch Medical Services, Washington, Missouri, United States
Billings Clinic, Billings, Montana, United States
Big Sky Oncology, Great Falls, Montana, United States
Montana Cancer Specialists, Missoula, Montana, United States
NE Hematology Oncology, PC, Lincoln, Nebraska, United States
Nebraska Methodist Hospital, Omaha, Nebraska, United States
Comp Cancer Centers of Nevada, Las Vegas, Nevada, United States
Ctr for Cancer & Hem Disease, Cherry Hill, New Jersey, United States
Forte, Attas & Schleider, Englewood, New Jersey, United States
Hunterdon Medical Center, Flemington, New Jersey, United States
Central State Medical Center, Freehold, New Jersey, United States
St. Barnabas Health Care Sys, Livingston, New Jersey, United States
Mountainside Hospital, Montclair, New Jersey, United States
Morristown Memorial Hospital, Morristown, New Jersey, United States
Hematology Oncology Assoc SJ, Mount Holly, New Jersey, United States
Jersey Shore Medical Center, Neptune, New Jersey, United States
Cancer Institute of New Jersey, New Brunswick, New Jersey, United States
The Valley Hospital, Paramus, New Jersey, United States
Overlook Hospital, Summit, New Jersey, United States
Holy Name Hospital, Teaneck, New Jersey, United States
San Juan Onco Assoc, Farmington, New Mexico, United States
Zale P Bernstein MD - PP, Buffalo, New York, United States
Bassett Cancer Center, Cooperstown, New York, United States
Adriondack Cancer Care, Glen Falls, New York, United States
BRANY, Great Neck, New York, United States
Queens Cancer Center, Jamaica, New York, United States
Crystal Run Health Care, Middletown, New York, United States
NYU Medical Center, New York, New York, United States
Mem Sloan Kettering Cancer Ctr, New York, New York, United States
SUNY Upstate, Syracuse, New York, United States
Presbyterian Hospital, Charlotte, North Carolina, United States
NorthEast Medical Center, Concord, North Carolina, United States
Moses Cone Reg Cncr Ctr, Greensboro, North Carolina, United States
Emerywood Hematology Oncology, High Point, North Carolina, United States
Carolina BioOncology Institute, Huntersville, North Carolina, United States
Kinston Medical Specialists, Kinston, North Carolina, United States
Beaufort County Hospital, Washington, North Carolina, United States
Summa Health System, Akron, Ohio, United States
Akron General Medical Center, Akron, Ohio, United States
Aultman Hospital, Canton, Ohio, United States
Gabrail Cancer Center, Canton, Ohio, United States
Onc/Hem Care Clin Trials LLC, Cincinnati, Ohio, United States
MetroHealth Medical Center, Cleveland, Ohio, United States
Mid Ohio Onc Hematology Inc, Columbus, Ohio, United States
Riverside Methodist Hospital, Columbus, Ohio, United States
Dayton Clinical Oncology Prog, Dayton, Ohio, United States
Ohio Cancer Specialists, Mansfield, Ohio, United States
Signal Point Hem/Oncology Inc, Middletown, Ohio, United States
Toledo Community Hospital, Toledo, Ohio, United States
Forum Health Cancer Care Ctr, Youngstown, Ohio, United States
Providence Portland Med Center, Portland, Oregon, United States
Ephrata Cancer Center, Ephrata, Pennsylvania, United States
Armstrong County Memorial Hosp, Kittanning, Pennsylvania, United States
Hem Onc Assoc Phys Lancaster, Lancaster, Pennsylvania, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Scranton Hematology Oncology, Scranton, Pennsylvania, United States
Assoc in Hematology Oncology, Upland, Pennsylvania, United States
Lankenau Medical Office Bldg, Wynnewood, Pennsylvania, United States
Charleston Cancer Center, Charleston, South Carolina, United States
Palmetto Hematology Oncology, Spartanburg, South Carolina, United States
Erlanger Health Systems, Chattanooga, Tennessee, United States
The Jones Clinic, Germantown, Tennessee, United States
Jackson-Madsion County Hosp, Jackson, Tennessee, United States
Clopton Clinic, Memphis, Tennessee, United States
Sarah Cannon Cancer Center, Nashville, Tennessee, United States
Vanderbilt University Medical, Nashville, Tennessee, United States
Lone Star Oncology Consultants, Austin, Texas, United States
Coastal Bend Cancer Center, Corpus Christi, Texas, United States
Texas Cancer Associates, Dallas, Texas, United States
Texas Hematology Oncology, Dallas, Texas, United States
JPS Center for Cancer Care, Fort Worth, Texas, United States
Univ of Texas Medical Branch, Galveston, Texas, United States
Wilford Hall Medical Center, Lackland AFB, Texas, United States
SW Vermont Healthcare Onc Asoc, Bennington, Vermont, United States
Vermont Ctr Cancer Medicine, Colchester, Vermont, United States
Community Cancer Center, Rutland, Vermont, United States
Peninsula Cancer Institute, Newport News, Virginia, United States
SW Virginia Hem Onc, Roanoke, Virginia, United States
Cascade Cancer Center, Kirkland, Washington, United States
Northwest Medical Specialists, Tacoma, Washington, United States
Univ Physicians Internal Med, Huntington, West Virginia, United States
West Virginia University, Morgantown, West Virginia, United States
Oncology Alliance, Glendale, Wisconsin, United States
Dean Clinic, Madison, Wisconsin, United States
Medical Consultants LTD, Milwaukee, Wisconsin, United States
All Saints Cancer Center, Racine, Wisconsin, United States
Hospital Pirovano, Buenos Aires, , Argentina
Hospital Britanico, Buenos Aires, , Argentina
Hospital Toru, Buenos Aires, , Argentina
CEMIC, Buenos Aires, , Argentina
Centro Oncologico de Cordoba, Cordoba, , Argentina
COIR, Mendoza, , Argentina
Instituto Medico Privado, Resistencia, , Argentina
Clinica Oncologica de Rosario, Rosario, , Argentina
ISIS Clinica Especializada, Sante Fe, , Argentina
Holy Spirit Hospital Northside, Chermside, QLD, , Australia
Sunshine Coast Cancer Centre, Nambour, QLD, , Australia
Sir Charles Gairdner Hospital, Nedlands, WA, , Australia
Burnside War Memorial Hospital, Toorak Gardens, SA, , Australia
Cliniques Univ St Luc, Brussels, , Belgium
CHR Citadelle Liege, Liege, , Belgium
Instituto Nacional do Cancer, Rio de Janeiro, , Brazil
Instituto de cancer Arnaldo, Sao Paulo, , Brazil
Hospital Das Clinicas, Sao Paulo, , Brazil
Regional Oncodispensary, Plovdiv, , Bulgaria
Regional Oncodispensary, Rousse, , Bulgaria
Regional Oncodispensary, Shoumen, , Bulgaria
Regional Oncodispensary, Sofia, , Bulgaria
UMHAT "Queen Joanna", Sofia, , Bulgaria
National Specialized Hospital, Sofia, , Bulgaria
Regional Oncodispensary, Stara Zagora, , Bulgaria
MHAT "St Marina", Varna, , Bulgaria
Regional Oncodispensary, Veliko Tarnovo, , Bulgaria
Princess Margaret Hospital, Hong Kong, , Hong Kong
Queen Elizabeth Hospital, Hong Kong, , Hong Kong
Queen Mary Hospital, Hong Kong, , Hong Kong
Tuen Mun Hospital, Hong Kong, , Hong Kong
Hadassah Medical Center, Jerusalem, , Israel
Sourasky Medical Center, Tel-Aviv, , Israel
Sheba Medical Center, Tel-Hashomer, , Israel
Azienda Ospedaliera Univ, Genova, , Italy
Ist Nazion per Ricerca Cancro, Genova, , Italy
Univ degli Studi di Napoli, Napoli, , Italy
Azienda Ospedaliera, Parma, , Italy
Azienda Osper di Perugia, Perugia, , Italy
Divisione Onc Med dell'Azienda, Udine, , Italy
Torre Medica Cristobal Colon, Acapulco, , Mexico
Inst Nacional de Cancerologia, Distrito Federal, , Mexico
ISSSTE Merida, Merida, , Mexico
Hospital de Especialidades, Torreon, Coahuila, , Mexico
Philippine General Hospital, Manila, Luzon, Philippines
The Medical City, Pasig City, Luzon, Philippines
Veterans Memorial Medical Ctr, Quezon City, Luzon, Philippines
Perpetual Succour Hospital, Cebu City, Visayas, Philippines
Univ of Santo Tomas Hospital, Manila, , Philippines
St Luke's Medical Center, Quezon City, , Philippines
Centrul de Onc Medical Lasi, Iasi, , Romania
Spitalul Clinic Judetean Sibiu, Sibiu, , Romania
Spitalul Judetean de Urgente, Suceava, , Romania
National Cancer Center, Singapore, , Singapore
Corporacio Sanitaria Parc, Sabadell, Barcelona, Spain
Hospital de Cruces, Barakaldo, , Spain
Hospital del Mar, Barcelona, , Spain
Hospital Clinic i Provincial, Barcelona, , Spain
Hospital Universitario, La Laguna, , Spain
Instituto Valenciano Oncologia, Valencia, , Spain
Hospital Clinico Universitario, Valencia, , Spain
China Medical Univ Hosp, Taichung, , Taiwan
National Taiwan University, Taipei, , Taiwan
Taichung Veterans Gen Hosp, Taiwan, , Taiwan
Bumrungrad International Hosp, Bangkok, , Thailand
National Cancer Institute, Bangkok, , Thailand
Pramongkutklao Hospital, Bangkok, , Thailand
Siriraj Hospital, Bangkok, , Thailand
Maharaj Nakorn Chiang Mai Hosp, Chiangmai, , Thailand
Bristol Heamatology & Onc Ctr, Bristol, , United Kingdom
Contact Details
Name: Donald Strickland, M.D.
Affiliation: Genentech, Inc.
Role: STUDY_DIRECTOR
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