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Brief Title: ENCOrafenib With Binimetinib in bRAF NSCLC
Official Title: A Phase II Study of the BRAF Inhibitor Encorafenib in Combination With the MEK Inhibitor Binimetinib in Patients With BRAFV600E-mutant Metastatic Non-small Cell Lung Cancer
Study ID: NCT04526782
Brief Summary: A Phase II study of the BRAF inhibitor Encorafenib in combination with the MEK inhibitor Binimetinib in Patients with BRAFV600E-mutant metastatic Non-small Cell Lung Cancer
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Annemasse - CH, Ambilly, , France
Angers - CHU, Angers, , France
Hôpital Privé d'Antony, Antony, , France
Avignon - Institut Sainte-Catherine, Avignon, , France
Bordeaux - Institut Bergonié, Bordeaux, , France
Boulogne - Ambroise Paré, Boulogne-Billancourt, , France
Brest - CHU, Brest, , France
Caen - CHU Côte de Nacre, Caen, , France
CH, Colmar, , France
Centre Hospitalier Intercommunal de Créteil, Créteil, , France
Centre Georges François Leclerc, Dijon, , France
CHRU Grenoble, Grenoble, , France
La Roche Sur Yon - CH, La Roche Sur Yon, , France
CH Le Mans, Le Mans, , France
CHRU de Lille, Lille, , France
CHU Dupuytren, Limoges, , France
Centre Léon Bérard, Lyon, , France
Institut Paoli Calmettes, Marseille, , France
AP-HM Hôpital Nord, Marseille, , France
Montpellier - CHRU, Montpellier, , France
Mulhouse - GHRMSA, Mulhouse, , France
Nancy - Institut de Cancérologie de Lorraine, Nancy, , France
Centre Antoine LACASSAGNE, Nice, , France
AP-HP Hôpital Cochin, Paris, , France
AP-HP Hôpital Tenon, Paris, , France
Hôpital BICHAT, Paris, , France
Paris - Institut Curie, Paris, , France
Centre Hospitalier Général - Pau, Pau, , France
Lyon - URCOT, Pierre-Bénite, , France
CHU Rennes - Hôpital Pontchaillou, Rennes, , France
CHU Charles Nicolle, Rouen, , France
Saint Quentin - CH, Saint Quentin, , France
Nouvel Hôpital Civil - Hôpitaux Universitaires de Strasbourg, Strasbourg, , France
CHU Toulouse - Pneumologie, Toulouse, , France
Tours - CHU, Tours, , France
Villefranche-Sur-Saône - Hôpital Nord-Ouest, Villefranche-Sur-Saône, , France
Gustave Roussy, Villejuif, , France
Name: David Planchard
Affiliation: Gustave Roussy (Villejuif - France)
Role: PRINCIPAL_INVESTIGATOR
Name: Charles Ricordel
Affiliation: CHU Rennes,France
Role: PRINCIPAL_INVESTIGATOR