Spots Global Cancer Trial Database for A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
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Trial Identification
Brief Title: A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
Official Title: A Phase III, Double-blind, Placebo-controlled, Randomised, Multicentre, International Study of Durvalumab Plus Oleclumab and Durvalumab Plus Monalizumab in Patients With Locally Advanced (Stage III), Unresectable Non-small Cell Lung Cancer (NSCLC) Who Have Not Progressed Following Definitive, Platinum-Based Concurrent Chemoradiation Therapy
Study ID: NCT05221840
Conditions
Study Description
Brief Summary: This is a Phase III, randomised, double-blind, multicentre, international study assessing the efficacy and safety of durvalumab (MEDI4736) in combination with oleclumab (MEDI9447) or durvalumab (MEDI4736) with monalizumab (IPH2201) in adults with locally advanced (Stage III), unresectable NSCLC, who have not progressed following platinum-based cCRT.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, San Diego, California, United States
Research Site, New Haven, Connecticut, United States
Research Site, Stuart, Florida, United States
Research Site, Urbana, Illinois, United States
Research Site, New Albany, Indiana, United States
Research Site, Waterloo, Iowa, United States
Research Site, Lexington, Kentucky, United States
Research Site, Louisville, Kentucky, United States
Research Site, Scarborough, Maine, United States
Research Site, Annapolis, Maryland, United States
Research Site, Baltimore, Maryland, United States
Research Site, Baltimore, Maryland, United States
Research Site, Bethesda, Maryland, United States
Research Site, Grand Rapids, Michigan, United States
Research Site, Duluth, Minnesota, United States
Research Site, Duluth, Minnesota, United States
Research Site, Billings, Montana, United States
Research Site, Ridgewood, New Jersey, United States
Research Site, Middletown, New York, United States
Research Site, Greensboro, North Carolina, United States
Research Site, Cleveland, Ohio, United States
Research Site, Cleveland, Ohio, United States
Research Site, Cleveland, Ohio, United States
Research Site, Independence, Ohio, United States
Research Site, Portland, Oregon, United States
Research Site, Philadelphia, Pennsylvania, United States
Research Site, Sioux Falls, South Dakota, United States
Research Site, Charlottesville, Virginia, United States
Research Site, Fairfax, Virginia, United States
Research Site, Richmond, Virginia, United States
Research Site, Richland, Washington, United States
Research Site, Spokane, Washington, United States
Research Site, Tacoma, Washington, United States
Research Site, Milwaukee, Wisconsin, United States
Research Site, Box Hill, , Australia
Research Site, East Melbourne, , Australia
Research Site, Elizabeth Vale, , Australia
Research Site, Gosford, , Australia
Research Site, Heidelberg, , Australia
Research Site, Kogarah, , Australia
Research Site, South Brisbane, , Australia
Research Site, St Albans, , Australia
Research Site, St. Leonards, , Australia
Research Site, Westmead, , Australia
Research Site, Barretos, , Brazil
Research Site, Belo Horizonte, , Brazil
Research Site, Florianópolis, , Brazil
Research Site, Fortaleza, , Brazil
Research Site, Jaú, , Brazil
Research Site, Natal, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Porto Alegre, , Brazil
Research Site, Recife, , Brazil
Research Site, Sao Paulo, , Brazil
Research Site, Uberlândia, , Brazil
Research Site, Vitoria, , Brazil
Research Site, Edmonton, Alberta, Canada
Research Site, Barrie, Ontario, Canada
Research Site, Hamilton, Ontario, Canada
Research Site, Kingston, Ontario, Canada
Research Site, London, Ontario, Canada
Research Site, Mississauga, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Rimouski, Quebec, Canada
Research Site, Anyang, , China
Research Site, Beijing, , China
Research Site, Beijing, , China
Research Site, Beijing, , China
Research Site, Changchun, , China
Research Site, Changsha, , China
Research Site, Changsha, , China
Research Site, Chongqing, , China
Research Site, Guangzhou, , China
Research Site, Guangzhou, , China
Research Site, Guangzhou, , China
Research Site, Hangzhou, , China
Research Site, Hangzhou, , China
Research Site, Hefei, , China
Research Site, Hefei, , China
Research Site, Jieyang, , China
Research Site, Kunming, , China
Research Site, Linhai, , China
Research Site, Nanchang, , China
Research Site, Nanning, , China
Research Site, Nantong, , China
Research Site, Neijiang, , China
Research Site, Ningbo, , China
Research Site, Shanghai, , China
Research Site, Shaoguan, , China
Research Site, Shenyang, , China
Research Site, Tianjin, , China
Research Site, Wuhan, , China
Research Site, Wuhan, , China
Research Site, Wuhan, , China
Research Site, Zhanjiang, , China
Research Site, Zhengzhou City, , China
Research Site, Zhengzhou, , China
Research Site, Zhongshan, , China
Research Site, Zhuhai, , China
Research Site, Barranquilla, , Colombia
Research Site, Barranquilla, , Colombia
Research Site, Bogota D.C., , Colombia
Research Site, Bogotá, , Colombia
Research Site, Medellin, , Colombia
Research Site, Valledupar, , Colombia
Research Site, Avignon Cedex 9, , France
Research Site, Besançon Cedex, , France
Research Site, Bordeaux, , France
Research Site, Clermont-Ferrand, , France
Research Site, Creteil Cedex, , France
Research Site, Lorient cedex, , France
Research Site, Marseille Cedex 20, , France
Research Site, Montpellier, , France
Research Site, Paris Cedex 5, , France
Research Site, Rennes Cedex 9, , France
Research Site, Rouen, , France
Research Site, Toulouse CEDEX 09, , France
Research Site, Villejuif Cedex, , France
Research Site, Erfurt, , Germany
Research Site, Erlangen, , Germany
Research Site, Essen, , Germany
Research Site, Esslingen, , Germany
Research Site, Georgsmarienhuette, , Germany
Research Site, Guetersloh, , Germany
Research Site, Hannover, , Germany
Research Site, Oldenburg, , Germany
Research Site, Würzburg, , Germany
Research Site, Brescia, , Italy
Research Site, Firenze, , Italy
Research Site, Lucca, , Italy
Research Site, Meldola, , Italy
Research Site, Orbassano, , Italy
Research Site, Parma, , Italy
Research Site, Pavia, , Italy
Research Site, Roma, , Italy
Research Site, Himeji-shi, , Japan
Research Site, Hiroshima-shi, , Japan
Research Site, Kashiwa, , Japan
Research Site, Kurume-shi, , Japan
Research Site, Natori-shi, , Japan
Research Site, Niigata-shi, , Japan
Research Site, Osaka-shi, , Japan
Research Site, Sendai-shi, , Japan
Research Site, Tokushima-shi, , Japan
Research Site, Toon-shi, , Japan
Research Site, Wakayama-shi, , Japan
Research Site, Changwon-si, , Korea, Republic of
Research Site, Cheongju-si, , Korea, Republic of
Research Site, Seongnam-si, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Suwon-si, , Korea, Republic of
Research Site, Suwon, , Korea, Republic of
Research Site, Arequipa, , Peru
Research Site, Concepción, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Trujillo, , Peru
Research Site, Brzozów, , Poland
Research Site, Bydgoszcz, , Poland
Research Site, Gdańsk, , Poland
Research Site, Koszalin, , Poland
Research Site, Poznań, , Poland
Research Site, Siedlce, , Poland
Research Site, Tomaszów Mazowiecki, , Poland
Research Site, Warszawa, , Poland
Research Site, Alcabideche, , Portugal
Research Site, Coimbra, , Portugal
Research Site, Lisboa, , Portugal
Research Site, Lisboa, , Portugal
Research Site, Lisboa, , Portugal
Research Site, Lisboa, , Portugal
Research Site, Loures, , Portugal
Research Site, Porto, , Portugal
Research Site, Novosibirsk, , Russian Federation
Research Site, Yekaterinburg, , Russian Federation
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Granada, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Santiago de Compostela, , Spain
Research Site, Valencia, , Spain
Research Site, Hsinchu, , Taiwan
Research Site, Taichung, , Taiwan
Research Site, Taichung, , Taiwan
Research Site, Taipei 112, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taoyuan City, , Taiwan
Research Site, Bangkok, , Thailand
Research Site, Bangkok, , Thailand
Research Site, Hat Yai, , Thailand
Research Site, Khon Kaen, , Thailand
Research Site, Khon Kaen, , Thailand
Research Site, Lampang, , Thailand
Research Site, Muang, , Thailand
Research Site, Muang, , Thailand
Research Site, Mueang, , Thailand
Research Site, Naimuang, , Thailand
Research Site, Ankara, , Turkey
Research Site, Ankara, , Turkey
Research Site, Ankara, , Turkey
Research Site, Diyarbakir, , Turkey
Research Site, Goztepe Istanbul, , Turkey
Research Site, Karsiyaka, , Turkey
Research Site, Chernihiv, , Ukraine
Research Site, Kharkiv Region, , Ukraine
Research Site, Kropyvnytskyi, , Ukraine
Research Site, Kyiv, , Ukraine
Research Site, Uzhgorod, , Ukraine
Research Site, Zaporizhzhia, , Ukraine
Research Site, Belfast, , United Kingdom
Research Site, Bristol, , United Kingdom
Research Site, Dundee, , United Kingdom
Research Site, Edinburgh, , United Kingdom
Research Site, Hampshire, , United Kingdom
Research Site, London, , United Kingdom
Research Site, London, , United Kingdom
Research Site, Middlesborough, , United Kingdom
Research Site, Poole, , United Kingdom
Research Site, Rhyl, , United Kingdom
Research Site, Torquay, , United Kingdom
Research Site, Truro, , United Kingdom
Research Site, Wolverhampton, , United Kingdom
Research Site, Hanoi, , Vietnam
Research Site, Ho Chi Minh city, , Vietnam
Research Site, Ho Chi Minh, , Vietnam
Contact Details
Name: Fabrice Barlesi, MD
Affiliation: Gustave Roussy, Cancer Campus, Grand Paris
Role: PRINCIPAL_INVESTIGATOR
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