Spots Global Cancer Trial Database for Study Comparing the Combination Domvanalimab and Zimberelimab With Pembrolizumab in Untreated Locally Advanced or Metastatic PD-L1-High Non-Small Cell Lung Cancer
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Trial Identification
Brief Title: Study Comparing the Combination Domvanalimab and Zimberelimab With Pembrolizumab in Untreated Locally Advanced or Metastatic PD-L1-High Non-Small Cell Lung Cancer
Official Title: A Phase 3 Study to Evaluate Zimberelimab (AB122) Combined With AB154 in Front-Line, PD-L1-High, Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Study ID: NCT04736173
Study Description
Brief Summary: This is a phase 3 study to evaluate zimberelimab (AB122) combined with domvanalimab (AB154) compared to pembrolizumab in front-line, PD-L1-high, locally advanced or metastatic NSCLC.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Millennium Reasearch & Clinical Development, Thousand Oaks, California, United States
Centricity Research, Columbus, Georgia, United States
Affinity Health Hope & Healing Cancer Services, Hinsdale, Illinois, United States
Gabrail Cancer Center, Canton, Ohio, United States
VA Notheast Ohio Healthcare System, Cleveland, Ohio, United States
Centricity Research Columbus Cancer Center, Columbus, Ohio, United States
Millennium Research, Houston, Texas, United States
Lumi Research, Kingwood, Texas, United States
Blue Ridge Cancer Center, Roanoke, Virginia, United States
Ahsania Mission Cancer and General Hospital, Dhaka, , Bangladesh
Bangladesh Cancer Society Hospital and Welfare Home, Dhaka, , Bangladesh
Kurmitola General Hospital, Dhaka, , Bangladesh
Hospital de Câncer de Barretos - Fundação Pio XII, Barretos, , Brazil
Associação Mário Pena - Núcleo de Ensino e Pesquisas Mário Penna, Belo Horizonte, , Brazil
Hospital DF Star, Brasília, , Brazil
CIONC-Centro Integrado de Oncologia de Curitiba, Curitiba, , Brazil
CEPON - Centro de Pesquisas Oncológicas de Santa Catarina, Florianópolis, , Brazil
Hospital de Caridade de Ijuí, Ijuí, , Brazil
Fundação Doutor Amaral Carvalho, Jaú, , Brazil
Instituto Mederi de Pesquisa e Saude, Passo Fundo, , Brazil
Santiago Escovar, Carlos Eugênio, Porto Alegre, , Brazil
Instituto de Oncologia Saint Gallen, Santa Cruz do Sul, , Brazil
CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia, Santo André, , Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José Do Rio Preto, , Brazil
IBCC - Instituto Brasileiro de Controle do Câncer, São Paulo, , Brazil
ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira, São Paulo, , Brazil
Hôpital Ambroise Paré, Boulogne-Billancourt, , France
Center Hospitalier Intercommunal de creteil, Créteil, , France
CHU de Poitiers, Poitiers, , France
CHU Rennes Hopital Pontchaillou, Rennes, , France
Hopital Larrey, Toulouse, , France
General Hospital of Athens "Alexandra", Athens, , Greece
General Hospital of Athens of Chest Diseases "SOTIRIA", Athens, , Greece
General Oncology Hospital of Kifissia "Agioi Anargyroi", Athens, , Greece
University General Hospital "Attikon", Athens, , Greece
University General Hospital of Larissa, Athens, , Greece
University General Hospital "Attikon", Chaïdári, , Greece
General Oncology Hospital of Kifissia " Agioi Anargyroi", Kifisiá, , Greece
General Hospital of Patra "Agios Andreas", Larissa, , Greece
University General Hospital "Attikon", Patra, , Greece
Hong Kong Integrated Oncology Centre, Hong Kong, , Hong Kong
Hong Kong United Oncology Centre, Hong Kong, , Hong Kong
Humanity and Health Clinical Trial Centre, Hong Kong, , Hong Kong
Princess Margaret Hospital, Hong Kong, , Hong Kong
Queen Mary Hospital, Hong Kong, , Hong Kong
Dong-A University Hospital, Busan, , Korea, Republic of
Kosin University Gospel Hospital, Busan, , Korea, Republic of
Chungbuk National University Hospital, Cheongju, , Korea, Republic of
Keimyung University Dongsan Hospital, Daegu, , Korea, Republic of
The Catholic University of Korea Eunpyeong St Mary's Hospital, Gyeonggi-do, , Korea, Republic of
Gyeongsang National University Hospital, Gyeongsang, , Korea, Republic of
Gachon University Gil Medical Centre, Incheon, , Korea, Republic of
Inha University Hospital, Incheon, , Korea, Republic of
The Catholic University of Korea Incheon St. Mary's Hospital, Incheon, , Korea, Republic of
Jeonbuk National University Hospital, Jeonju, , Korea, Republic of
Cha Bundang Medical Centre Cha University, Seongnam, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Asan Medical Centre, Seoul, , Korea, Republic of
Gangnam Severance Hospital, Seoul, , Korea, Republic of
Kangbuk Samsung Hospital, Seoul, , Korea, Republic of
Korea University Anam Hospital, Seoul, , Korea, Republic of
The Catholic University of Korea Seoul St Mary's Hospital, Seoul, , Korea, Republic of
Ajou University Hospital, Suwon-Si, , Korea, Republic of
The Catholic University of Korea St. Vincent Hospital, Suwon-Si, , Korea, Republic of
Pusan National University Yangsan Hospital, Yangsan, , Korea, Republic of
Universiti Kebangsaan Malaysia, Cheras, , Malaysia
Institut Kanser Negara, Jalan Baharu, , Malaysia
Hospital Sultan Ismail, Johor Bahru, , Malaysia
Hospital Kuala Lumpar, Kuala Lumpur, , Malaysia
Pantai Hospital Kuala Lumpur, Kuala Lumpur, , Malaysia
University Malaya Medical Centre, Kuala Lumpur, , Malaysia
Hospital Tengku Ampuan Afzan, Kuantan, , Malaysia
Hospital Umum Sarawak, Kuching, , Malaysia
Hospital Pulau Pinang, Pulau Pinang, , Malaysia
Mount Miriam Cancer Hospital, Tanjung Bungah, , Malaysia
Health Pharma Professional Research, Benito Juarez, , Mexico
Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, , Mexico
Hospital Civil Fray Antonio Alcalde, Guadalajara, , Mexico
Health Pharma Professional Research S.A. de C.V., Mexico City, , Mexico
Universidad Autonoma de Nuevo Leon, Hospital Universitario Dr. Jose Eleuterio Gonzalez, Monterrey, , Mexico
Oaxaca Site Management Organization S.C., Oaxaca, , Mexico
Oncologico Potosino, San Luis Potosi, , Mexico
Hospital Goyeneche, Arequipa, , Peru
Oncosalud, San Borja, , Peru
Clinica Ricardo Palma, San Isidro, , Peru
Baguio General Hospital Medical Centre, Baguio City, , Philippines
Chung Shan Medical University Hospital, Cebu City, , Philippines
Chong Hua Hospital, Cebu, , Philippines
Metro Davao Medical and Research Centre, Davao City, , Philippines
Makati Medical Centre, Makati City, , Philippines
Philippine General Hospital, Manila, , Philippines
University of Santo Tomas Hospital, Manila, , Philippines
St. Luke Medical Centre Quezon City, Quezon City, , Philippines
Clinical Center "Bezanijska kosa", Belgrade, , Serbia
Clinical Center of Serbia, Belgrade, , Serbia
Oncomed System, Belgrade, , Serbia
Clinical Center Kragujevac, Kragujevac, , Serbia
Clinical Center Nis, Nis, , Serbia
Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, , Serbia
General Hospital Uzice, Uzice, , Serbia
Slovak Research Center- team member, Ambulancia klinickej onkologie, Banka, , Slovakia
Vychodoslovensky onkologicky ustav, a.s., Kosice, , Slovakia
Nemocnica s poliklinikou Stefana Kukuru Michalovce, a.s., Michalovce, , Slovakia
Nemocnica na okraji mesta, n.o., Partizanske, , Slovakia
Fakultna nemocnica Trnava, Trnava, , Slovakia
Tygerberg Hospital, Cape Town, , South Africa
Exellentis Clinical Trial Consultants, George, , South Africa
Cancercare PE, Johannesburg, , South Africa
The Medical Oncology Centre of Rosebank, Johannesburg, , South Africa
West Rand Oncology Centre, Johannesburg, , South Africa
Wits Clinical Research CMJAH Clinical Trial Site, Johannesburg, , South Africa
Port Elizabeth Oncology Centre-Cancercare, Port Elizabeth, , South Africa
Little Company of Mary Oncology Centre - Mary Potter Cancer Centre, Pretoria, , South Africa
University of Pretoria Medical Oncology, Pretoria, , South Africa
Wilgers Oncology Centre, Pretoria, , South Africa
Chang Gung Medical Foundation Kaohsiung, Kaohsiung City, , Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City, , Taiwan
China Medical University Hospital, Taichung City, , Taiwan
Chung Shan Medical University Hospital, Taichung City, , Taiwan
Taichung Veterans General Hospital, Taichung City, , Taiwan
Chung Shan Medical University Hospital, Taichung, , Taiwan
Taipei Medical University Hospital, Taipei, , Taiwan
King Chulalongkorn Memorial Hospital, Bangkok, , Thailand
Phramongkutklao Hospital, Bangkok, , Thailand
Police General Hospital, Bangkok, , Thailand
Rajavithi Hospital, Bangkok, , Thailand
Siriraj Hospital, Bangkok, , Thailand
Vajira Hospital, Bangkok, , Thailand
Prapokklao Hospital, Chanthaburi, , Thailand
Maharaj Nakorn Chiang Mai Hospital, Chiang Mai, , Thailand
Nakornping Hospital, Chiang Mai, , Thailand
Srinagarind Hospital, Khon Kaen, , Thailand
Lampang Hospital, Lampang, , Thailand
Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, , Thailand
HRH Princess Maha Chakri Sirindhorn Medical Centre, Ongkharak, , Thailand
Buddhachinaraj Phitsanulok Hospital, Phitsanulok, , Thailand
Naresuan University Hospital, Phitsanulok, , Thailand
Saraburi Hospital, Saraburi, , Thailand
Songkhlanagarind Hospital, Songkhla, , Thailand
Sunpasitthiprasing Hospital, Ubon Ratchathani, , Thailand
Udon Thani Hospital, Udon Thani, , Thailand
Adana City Hospital, Adana, , Turkey
Baskent University Adana Application and Research Center, Adana, , Turkey
Cukurova University Medical Faculty, Adana, , Turkey
Ankara City Hospital, Ankara, , Turkey
Gazi University Medical Faculty, Ankara, , Turkey
Hacettepe University Medical Faculty, Ankara, , Turkey
Memorial Ankara Hospital, Ankara, , Turkey
Dicle University, Medical faculty, Diyarbakir, , Turkey
Trakya University Medical Faculty, Edirne, , Turkey
Acibadem Atakent Hospital, Istanbul, , Turkey
Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, , Turkey
Istanbul University Cerrahpasa - Cerrahpasa Medical Faculty, Istanbul, , Turkey
Medipol University Medical Faculty, Istanbul, , Turkey
Kocaeli Universitesi Tip Fakultesi, Kocaeli, , Turkey
Inonu Uni. Med. Fac., Malatya, , Turkey
Mersin University Medical Faculty, Mersin, , Turkey
Cần Thơ Oncology Hospital, Cần Thơ, , Vietnam
Pham Ngo Thach Hospital, Ho Chi Minh City, , Vietnam
Huế Central Hospital, Huế, , Vietnam
103 Military Hospital, Hà Nội, , Vietnam
175 Military Hospital, Hà Nội, , Vietnam
Bach Mai Hospital, Hà Nội, , Vietnam
Chợ Rẫy Hospital, Hà Nội, , Vietnam
Hanoi Oncology Hospital, Hà Nội, , Vietnam
HCM Oncology Hospital, Hà Nội, , Vietnam
Ho Chi Minh City University Medical Centre, Hà Nội, , Vietnam
National Lung Hospital, Hà Nội, , Vietnam
Nghe An Oncology Hospital, Hà Nội, , Vietnam
People's Hospital 115, Hà Nội, , Vietnam
Vietnam National Cancer Hospital, Hà Nội, , Vietnam
Contact Details
Name: Medical Director
Affiliation: Arcus Biosciences, Inc.
Role: STUDY_DIRECTOR
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