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Brief Title: A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer
Official Title: A Randomized, Open-Label, Controlled, Multi-center Phase Ⅲ Study of Camrelizumab Combined With Famitinib Malate Versus Pembrolizumab in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer
Study ID: NCT05042375
Brief Summary: The study is being conducted to evaluate the efficacy, and safety of camrelizumab combined with famitinib malate vs. pembrolizumab in treatment naïve subjects with programmed death-ligand 1(PD-L1)-positive recurrent or metastatic non-small cell lung cancer (NSCLC).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China
Anhui Chest Hospital, Hefei, Anhui, China
Anhui Provincial Cancer Hospital, Hefei, Anhui, China
Anhui Provincial Hospital, Hefei, Anhui, China
The First Affiliated Hospital Of Anhui Medical University, Hefei, Anhui, China
Beijing Cancer Hospital, Beijing, Beijing, China
Beijing Chest Hospital,Capital Medical University, Beijing, Beijing, China
Peking University Third Hospital, Beijing, Beijing, China
ChongQing University Cancer Hospital, Chongqing, Chongqing, China
Fujian Medical University Union Hospital, Fuzhou, Fujian, China
Fujian Provincial Cancer Hospital, Fuzhou, Fujian, China
The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China
The Second Affiliated Hospital of Xiamen Medical College, Xiamen, Fujian, China
The People's Hospital of Gaozhou, Gaozhou, Guangdong, China
Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, Guangdong, China
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
Meizhou People's Hospital (Huangtang Hospital), Meizhou, Guangdong, China
Shantou Central Hospital, Shantou, Guangdong, China
Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China
Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, China
Guangxi Medical University Affiliated Tumor Hospital, Nanning, Guangxi, China
The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China
Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China
Hainan General Hospital, Haikou, Hainan, China
The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China
North China University Of Science And Technology Affiliated Hospital, Tangshan, Hebei, China
Xingtai People's Hospital, Xingtai, Hebei, China
Haerbin Medical University Cancer Hospital, Ha'erbin, Heilongjiang, China
Anyang Cancer Hospital, Anyang, Henan, China
The First Affiliated Hosptial of Henan University of Science & Technology, Luoyang, Henan, China
Henan Cancer Hospital, Zhengzhou, Henan, China
The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
Shiyan Taihe Hospital, Shiyan, Hubei, China
Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, China
Xiangyang Central Hospital, Xiangyang, Hubei, China
Army Medical Center of PLA, Changsha, Hunan, China
Hunan Cancer Hospital-Thoracic Medicine Department I, Changsha, Hunan, China
Hunan Cancer Hospital-Thoracic Medicine Department Ⅱ, Changsha, Hunan, China
Xiangya Hospital Central South University, Changsha, Hunan, China
Shaoyang Central Hospital, Shaoyang, Hunan, China
Zhuzhou Central Hospital, Zhuzhou, Hunan, China
Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China
Zhongda Hospital Southeast University, Nanjing, Jiangsu, China
Nantong Tumor Hospital, Nantong, Jiangsu, China
Affiliated Hospital of JiangNan University, Wuxi, Jiangsu, China
The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China
Northern Jiangsu People's Hospital, Yangzhou, Jiangsu, China
First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China
The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
Liaoning Cancer Hospital, Shenyang, Liaoning, China
Shengjing Hospital Affiliated to China Medical University, Shenyang, Liaoning, China
The First Hospital of China Medical University, Shenyang, Liaoning, China
Chifeng City Hospital, Chifeng, Neimenggu, China
The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Neimenggu, China
Qilu Hospital of Shandong University, Jinan, Shandong, China
Shandong Cancer Hospital&Institute, Jinan, Shandong, China
The Affiliated of Qingdao University, Qingdao, Shandong, China
LinYi Cancer Hospital, Linyi, Shangdong, China
Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
Shanghai Chest Hospital, Shanghai, Shanghai, China
Shanghai Pulmonary Hospital, Shanghai, Shanghai, China
Baoji Central Hospital, Baoji, Shanxi, China
Changzhi People's Hospital, Changzhi, Shanxi, China
General Hospital of TISCO, Taiyuan, Shanxi, China
Shanxi Bethune Hospital, Taiyuan, Shanxi, China
Shanxi Provincial Cancer Hospital, Taiyuan, Shanxi, China
The Second Affiliated Hospital of Air Force Military University Tangdu Hospital, Xi'an, Shanxi, China
Sichuan Cancer Hospital, Chengdu, Sichuan, China
The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China
Mianyang Central Hospital, Mianyang, Sichuan, China
Yibin Second People's Hospital, Yibin, Sichuan, China
Tianjin Medical University Cancer Institute & Hospital, Tianjin, Tianjin, China
Yunnan Cancer Hospital, Kunming, Yunnan, China
Hangzhou Cancer Hospital, Hangzhou, Zhejiang, China
The First Affiliated Hospital, College of Medicine, Zhejiang University of Medicine, Hangzhou, Zhejiang, China
The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
ZheJiang Cancer Hospital, Hangzhou, Zhejiang, China