Spots Global Cancer Trial Database for Phase 1b/2 Trial of AMG386 With Pemetrexed and Carboplatin in Non-Small Cell Lung Cancer
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Trial Identification
Brief Title: Phase 1b/2 Trial of AMG386 With Pemetrexed and Carboplatin in Non-Small Cell Lung Cancer
Official Title: A Phase 1b/2 Trial of AMG 386 in Combination With Pemetrexed and Carboplatin as First Line Treatment of Metastatic Non-Squamous Non-Small Cell Lung Cancer
Study ID: NCT01666977
Conditions
Study Description
Brief Summary: The purpose of this phase 1b/2 study is to estimate the treatment effect of study drug measuring progression free survival.
Detailed Description: To evaluate the incidence of adverse events and clinical laboratory abnormalities defined as dose-limiting toxicity in subjects with metastatic non-squamous non-small cell lung cancer (NSCLC) treated with AMG 386 in combination with pemetrexed and carboplatin
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Fayetteville, Arkansas, United States
Research Site, Hot Springs, Arkansas, United States
Research Site, Los Angeles, California, United States
Research Site, Palm Springs, California, United States
Research Site, Pleasant Hill, California, United States
Research Site, San Diego, California, United States
Research Site, Santa Monica, California, United States
Research Site, Peoria, Illinois, United States
Research Site, Paducah, Kentucky, United States
Research Site, Hannover, New Hampshire, United States
Research Site, Bronx, New York, United States
Research Site, Bismarck, North Dakota, United States
Research Site, Greenville, South Carolina, United States
Research Site, Camperdown, New South Wales, Australia
Research Site, Kogarah, New South Wales, Australia
Research Site, Randwick, New South Wales, Australia
Research Site, Tweed Heads, New South Wales, Australia
Research Site, Herston, Queensland, Australia
Research Site, Bentleigh East, Victoria, Australia
Research Site, Heidelberg, Victoria, Australia
Research Site, Bruxelles, , Belgium
Research Site, Hamilton, Ontario, Canada
Research Site, Oshawa, Ontario, Canada
Research Site, Ottawa, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Laval, Quebec, Canada
Research Site, Levis, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Heraklion, , Greece
Research Site, Larissa, , Greece
Research Site, Patra, , Greece
Research Site, Thessaloniki, , Greece
Research Site, Málaga, Andalucía, Spain
Research Site, Zaragoza, Aragón, Spain
Research Site, Madrid, , Spain
Contact Details
Name: MD
Affiliation: Amgen
Role: STUDY_DIRECTOR
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