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Brief Title: ASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung Cancer
Official Title: A Phase III, Randomized, Double-Blind, Placebo-Controlled Multi-Center Study of ASA404 in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Locally Advanced or Metastatic (Stage IIIb/IV) Non-Small Cell Lung Cancer (NSCLC)
Study ID: NCT00662597
Brief Summary: The purpose of this study is to determine if adding ASA404 to standard chemotherapy makes the cancer treatment more effective in patients with advanced lung cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of South Alabama/Mitchell Cancer Institute, Mobile, Alabama, United States
Arizona Oncology Associates, Tucson, Arizona, United States
University of Arizona Cancer Center, Tucson, Arizona, United States
Highlands Oncology Group, Bentonville, Arkansas, United States
Genesis Cancer Center, Hot Springs, Arkansas, United States
Alta Bates Summit Medical Center, Berkeley, California, United States
Pacific Oncology and Hematology Association, Encinitas, California, United States
Cancer Care Associates, Fresno, California, United States
Ronald Yanagihara - Private Practice, Gilroy, California, United States
California Cancer Care, Greenbrae, California, United States
Moores UCSD Cancer Center, La Jolla, California, United States
Loma Linda University Cancer Center, Loma Linda, California, United States
Cedars Sinai Medical Center, Los Angeles, California, United States
University of California Irvine Comprhensive Center, Orange, California, United States
Loma Linda Oncology Medical Group, Inc., Redlands, California, United States
UC Davis Comprehensive Cancer Center, Sacramento, California, United States
California Pacific Medical Research Institute, San Francisco, California, United States
Redwood Regional Cancer Center, Santa Rosa, California, United States
Georgetown University Hospital, Washington, District of Columbia, United States
Palm Beach Institute of Hematology & Oncology, Boynton Beach, Florida, United States
Florida Cancer Specialists, Bradenton, Florida, United States
Cancer Centers of Central Florida, PA, Leesburg, Florida, United States
Advanced Medical Specialties (ACORN), Miami, Florida, United States
Northwest Georgia Oncology Centers, Marietta, Georgia, United States
Cancer Research Center of Hawaii, Honolulu, Hawaii, United States
Kootenai Cancer Center (ACORN), Coeur d'Alene, Idaho, United States
Advocate Illinois Masonic Medical Center, Chicago, Illinois, United States
Illinois Oncology/Warren Billhartz Cancer Ctr., Maryville, Illinois, United States
Loyola University Medical Center, Maywood, Illinois, United States
Hematology/Oncology of North Shore, Skokie, Illinois, United States
Loyola Cancer Care & Research Ctr. at Central Dupage Hospital, Winfield, Illinois, United States
Ft. Wayne Oncology and Hematology, Fort Wayne, Indiana, United States
Siouxland Hematology-Oncology Assoc., LLC, Sioux City, Iowa, United States
Kansas City Cancer Center, Southwest, Overland Park, Kansas, United States
University of Louisville - James Graham Brown Cancer Center, Louisville, Kentucky, United States
Hematology Oncology Specialists, Metairie, Louisiana, United States
Louisiana State University Health Sciences Center - Feist-Weiller Cancer Center, Shreveport, Louisiana, United States
St. Agnes Cancer Center, Baltimore, Maryland, United States
Sinai Hospital of Baltimore - The Alvin & Lois Lapidus Cancer Institute, Baltimore, Maryland, United States
The Harry and Jeanette Weinberg Cancer Institute at Franklin Square/MedStar Health, Baltimore, Maryland, United States
Peninsula Regional Oncology and Hematology, Salisbury, Maryland, United States
Boston VA Healthcare System, Boston, Massachusetts, United States
Fallon Clinic, Worcester, Massachusetts, United States
Breslin Cancer Center, Lansing, Michigan, United States
Osteopathic Medical Oncology and Hematology PC, Woodhaven, Michigan, United States
St. Luke's Hospital - St Luke's Cancer Center, Duluth, Minnesota, United States
Kansas City Veterans Affair Medical Center, Kansas City, Missouri, United States
St. Louis University Cancer Center, Saint Louis, Missouri, United States
Center for Cancer Care and Research (US Oncology), Saint Louis, Missouri, United States
St. John's Mercy Medical Center, Saint Louis, Missouri, United States
St. Louis Cancer and Breast Institute, Saint Louis, Missouri, United States
Billings Clinic, Billings, Montana, United States
Sletten Cancer Institute, Great Falls, Montana, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
Eastchester Center for Cancer Care, Bronx, New York, United States
Arena Oncology Associates, Lake Success, New York, United States
New York Oncology Hematology, Latham, New York, United States
Hematology Oncology Associates of Rockland, Nyack, New York, United States
Rochester General Hospital - Lipson Cancer Center, Rochester, New York, United States
Syracuse VA Medical Center, Syracuse, New York, United States
Alamance Regional Medical Center-Cancer Ctr., Burlington, North Carolina, United States
Carolina Cancer Mgmt/Cape Fear Valley Health System/Med Onc, Fayetteville, North Carolina, United States
Akron City Hospital, Akron, Ohio, United States
Oncology Hematology Care Research, Cincinnati, Ohio, United States
University Hospitals of Cleveland, Cleveland, Ohio, United States
Medical Oncology Hematology Associates, Inc. - Dayton Clinical Oncology Program, Dayton, Ohio, United States
Medical Oncology Hematology Associates, Inc., Dayton, Ohio, United States
Cleo Craig Memorial Cancer Ctr. & Research Clinic, Lawton, Oklahoma, United States
University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, United States
Kaiser Permanente, Northwest Region, Portland, Oregon, United States
Allegheny General Hospital/Allegheny Cancer Center, Pittsburgh, Pennsylvania, United States
South Carolina Oncology Associate, Columbia, South Carolina, United States
Lowcountry Hematology & Oncology PA, Mount Pleasant, South Carolina, United States
Chattanooga Oncology Hematology Associates, Chattanooga, Tennessee, United States
The West Clinic, Memphis, Tennessee, United States
Tennessee Oncology, Nashville, Tennessee, United States
Texas Oncology Cancer Center of the High Plains, Amarillo, Texas, United States
Arlington Cancer Center, Arlington, Texas, United States
Patient's Comprehensive Cancer Center, Carrollton, Texas, United States
South Texas Cancer Institute, Corpus Christi, Texas, United States
Cancer Care Centers of South Texas, Dallas, Texas, United States
Texas Oncology at Presbyterian Hospital, Dallas, Texas, United States
University of Texas Southwestern Medical Center/Simmons Comprehensive Cancer Center, Dallas, Texas, United States
Texas Oncology at Garland, Garland, Texas, United States
HOPE Oncology, Richardson, Texas, United States
Tyler Cancer Center, Tyler, Texas, United States
UT Health Center, Tyler, Texas, United States
Deke Slayton Cancer Center, Webster, Texas, United States
Texoma Cancer Center, Wichita Falls, Texas, United States
Northern Utah Associates, Ogden, Utah, United States
Danville Hematology & Oncology, Danville, Virginia, United States
Medical Oncology & Hematology Associates of Northern Virginia, Fairfax, Virginia, United States
Virginia Oncology Associates, Norfolk, Virginia, United States
Virginia Cancer Institute, Richmond, Virginia, United States
Highline Medical Oncology, Burien, Washington, United States
Providence Everett Medical Center/Providence regional Cancer Partnership, Everett, Washington, United States
Northwest Cancer Specialists, Vancouver, Washington, United States
University of Wisconsin, Madison, Wisconsin, United States
Medical Consultants, Milwaukee, Wisconsin, United States
Medical College of Wisconsin/Division of Neoplastic & Related Disorders, Milwaukee, Wisconsin, United States
Novartis Investigative Site, Buenos Aires, , Argentina
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Novartis Investigative Site, Rosario, , Argentina
Novartis Investigative Site, Heidelberg, , Australia
Novartis Investigative Site, Herston, , Australia
Novartis Investigative Site, South Brisbane, , Australia
Novartis Investigative Site, Duffel, , Belgium
Novartis Investigative Site, Jette, , Belgium
Novartis Investigative Site, Liege, , Belgium
Novartis Investigative Site, Barretos, , Brazil
Novartis Investigative Site, Belo Horizonte, , Brazil
Novartis Investigative Site, Goiania, , Brazil
Novartis Investigative Site, Jaù, , Brazil
Novartis Investigative Site, Jaú, , Brazil
Novartis Investigative Site, Porto Alegre, , Brazil
Novartis Investigative Site, Santo Andre, , Brazil
Novartis Investigative Site, Sao Paulo, , Brazil
Novartis Investigative Site, São Paulo, , Brazil
Novartis Investigative Site, Calgary, , Canada
Novartis Investigative Site, Greenfield Park, , Canada
Novartis Investigative Site, Kitchener, , Canada
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Novartis Investigative Site, Montreal, , Canada
Novartis Investigative Site, Rimouski, , Canada
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Novartis Investigative Site, Saint Herblain, , France
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Novartis Investigative Site, Bad Berka, , Germany
Novartis Investigative Site, Berlin, , Germany
Novartis Investigative Site, Donaustauf, , Germany
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Novartis Investigative Site, Essen, , Germany
Novartis Investigative Site, Freiburg, , Germany
Novartis Investigative Site, Gerlingen, , Germany
Novartis Investigative Site, Grosshandsdorf, , Germany
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Novartis Investigative Site, Leipzig, , Germany
Novartis Investigative Site, Merseburg, , Germany
Novartis Investigative Site, Muenchen, , Germany
Novartis Investigative Site, Nuernberg, , Germany
Novartis Investigative Site, Athens, , Greece
Novartis Investigative Site, Heraklion Crete, , Greece
Novartis Investigative Site, Thessaloniki, , Greece
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Novartis Investigative Site, Budapest, , Hungary
Novartis Investigative Site, Deszk, , Hungary
Novartis Investigative Site, Mátraháza, , Hungary
Novartis Investigative Site, Kfar-Sava, , Israel
Novartis Investigative Site, Rehovot, , Israel
Novartis Investigative Site, Tel-Aviv, , Israel
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Novartis Investigative Site, Zrifin, , Israel
Novartis Investigative Site, Avellino, , Italy
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Novartis Investigative Site, Modena, , Italy
Novartis Investigative Site, Napoli, , Italy
Novartis Investigative Site, Orbassano, , Italy
Novartis Investigative Site, Parma, , Italy
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Novartis Investigative Site, Roma, , Italy
Novartis Investigative Site, Akashi, , Japan
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Novartis Investigative Site, Hiroshima, , Japan
Novartis Investigative Site, Kashiwa, , Japan
Novartis Investigative Site, Kobe-city, , Japan
Novartis Investigative Site, Koto, , Japan
Novartis Investigative Site, Kumamoto, , Japan
Novartis Investigative Site, Kurashiki, , Japan
Novartis Investigative Site, Matsuyama, , Japan
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Novartis Investigative Site, Niigata, , Japan
Novartis Investigative Site, Okayama, , Japan
Novartis Investigative Site, Osaka Sayama, , Japan
Novartis Investigative Site, Osaka, , Japan
Novartis Investigative Site, Sapporo, , Japan
Novartis Investigative Site, Sendai, , Japan
Novartis Investigative Site, Ube, , Japan
Novartis Investigative Site, Yokohama, , Japan
Novartis Investigative Site, Seoul, , Korea, Republic of
Novartis Investigative Site, Seungnam, , Korea, Republic of
Novartis Investigative Site, Suwon, , Korea, Republic of
Novartis Investigative Site, Amsterdam, , Netherlands
Novartis Investigative Site, Breda, , Netherlands
Novartis Investigative Site, Eindhoven, , Netherlands
Novartis Investigative Site, Harderwijk, , Netherlands
Novartis Investigative Site, Hertogenbosch, , Netherlands
Novartis Investigative Site, Zwolle, , Netherlands
Novartis Investigative Site, Auckland, , New Zealand
Novartis Investigative Site, Christchurch, , New Zealand
Novartis Investigative Site, Hamilton, , New Zealand
Novartis Investigative Site, Wellington, , New Zealand
Novartis Investigative Site, Lodz, , Poland
Novartis Investigative Site, Lublin, , Poland
Novartis Investigative Site, Otwock, , Poland
Novartis Investigative Site, Poznan, , Poland
Novartis Investigative Site, Singapore, , Singapore
Novartis Investigative Site, Baracaldo, , Spain
Novartis Investigative Site, Barcelona, , Spain
Novartis Investigative Site, Córdoba, , Spain
Novartis Investigative Site, Granada, , Spain
Novartis Investigative Site, Jaen, , Spain
Novartis Investigative Site, Madrid, , Spain
Novartis Investigative Site, Pontevedra, , Spain
Novartis Investigative Site, Sevilla, , Spain
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Novartis Investigative Site, Umea, , Sweden
Novartis Investigative Site, Kaoshiung, , Taiwan
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Novartis Investigative Site, Tainan, , Taiwan
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Novartis Investigative Site, Altunizade, , Turkey
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Novartis Investigative Site, Istanbul, , Turkey
Novartis Investigative Site, Izmir, , Turkey
Novartis Investigative Site, Aberdeen, , United Kingdom
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Novartis Investigative Site, Leicester, , United Kingdom
Novartis Investigative Site, London, , United Kingdom
Novartis Investigative Site, Manchester, , United Kingdom
Novartis Investigative Site, Sutton, , United Kingdom
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR