Spots Global Cancer Trial Database for Comprehensive Genomic Analysis in Tissue and Blood Samples From Young Patients With Lung Cancer
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Trial Identification
Brief Title: Comprehensive Genomic Analysis in Tissue and Blood Samples From Young Patients With Lung Cancer
Official Title: Genomics of Young Lung Cancer Study
Study ID: NCT02273336
Study Description
Brief Summary: This research trial studies genomic analysis in tissue and blood samples from young patients with lung cancer. Identifying specific gene mutations (changes in deoxyribonucleic acid \[DNA\]) may help doctors tailor treatment to target the specific mutations and help plan effective treatment.
Detailed Description: PRIMARY OBJECTIVES: I. To perform comprehensive genomic analysis of young lung cancer patients' samples to facilitate delivery of targeted therapies and clinical trial enrollment. II. To characterize the impact of young age at lung cancer diagnosis on the genomic landscape of primary lung cancer. III. To establish a prospective registry of young lung cancer patients for both tumor and germline next generation sequencing. OUTLINE: Tissue and blood samples are analyzed via next generation sequencing and whole exome sequencing. After completion of study, patients are followed up every 3 months for up to 3 years.
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
USC Norris Comprehensive Cancer Center, Los Angeles, California, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Contact Details
Name: Barbara Gitlitz, MD
Affiliation: University of Southern California
Role: PRINCIPAL_INVESTIGATOR
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