Spots Global Cancer Trial Database for Study of XB002 in Subjects With Solid Tumors (JEWEL-101)
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Trial Identification
Brief Title: Study of XB002 in Subjects With Solid Tumors (JEWEL-101)
Official Title: A Dose-Escalation and Expansion Study of the Safety and Pharmacokinetics of XB002 as Single-Agent and Combination Therapy in Subjects With Inoperable Locally Advanced or Metastatic Solid Tumors
Study ID: NCT04925284
Study Description
Brief Summary: This is a Phase 1, open-label, multicenter, dose-escalation and expansion study evaluating the safety, tolerability, PK, pharmacodynamics, and clinical antitumor activity of XB002 administered IV q3w alone and in combination with nivolumab to subjects with advanced solid tumors.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Exelixis Clinical Site #48, Birmingham, Alabama, United States
Exelixis Clinical Site #20, Tucson, Arizona, United States
Exelixis Clinical Site#58, Little Rock, Arkansas, United States
Exelixis Clinical Site#59, Fountain Valley, California, United States
Exelixis Clinical Site #21, Los Angeles, California, United States
Exelixis Clinical Site #26, Los Angeles, California, United States
Exelixis Clinical Site #16, New Haven, Connecticut, United States
Exelixis Clinical Site #22, Washington, District of Columbia, United States
Exelixis Clinical Site #6, Baltimore, Maryland, United States
Exelixis Clinical Site #18, Columbia, Maryland, United States
Exelixis Clinical Site #25, Boston, Massachusetts, United States
Exelixis Clinical Site #19, Detroit, Michigan, United States
Exelixis Clinical Site #10, Detroit, Michigan, United States
Exelixis Clinical Site #5, Saint Louis, Missouri, United States
Exelixis Clinical Site #11, Omaha, Nebraska, United States
Exelixis Clinical Site #8, East Brunswick, New Jersey, United States
Exelixis Clinical Site #7, New Brunswick, New Jersey, United States
Exelixis Clinical Site #23, Albany, New York, United States
Exelixis Clinical Site#67, Lake Success, New York, United States
Exelixis Clinical Site #12, New York, New York, United States
Exelixis Clinical Site #15, Cleveland, Ohio, United States
Exelixis Clinical Site #29, Cleveland, Ohio, United States
Exelixis Clinical Site #49, Hilliard, Ohio, United States
Exelixis Clinical Site #4, Oklahoma City, Oklahoma, United States
Exelixis Clinical Site #3, Nashville, Tennessee, United States
Exelixis Clinical Site #24, Austin, Texas, United States
Exelixis Clinical Site #1, Austin, Texas, United States
Exelixis Clinical Site #32, Dallas, Texas, United States
Exelixis Clinical Site #14, Dallas, Texas, United States
Exelixis Clinical Site#92, Houston, Texas, United States
Exelixis Clinical Site #2, San Antonio, Texas, United States
Exelixis Clinical Site #9, Charlottesville, Virginia, United States
Exelixis Clinical Site#75, Miranda, New South Wales, Australia
Exelixis Clinical Site#70, Nedlands, Western Australia, Australia
Exelixis Clinical Site #37, Darlinghurst, , Australia
Exelixis Clinical Site #44, Liverpool, , Australia
Exelixis Clinical Site #35, Saint Leonards, , Australia
Exelixis Clinical Site#71, Charleroi, Hainaut, Belgium
Exelixis Clinical Site#66, Liège, Liege, Belgium
Exelixis Clinical Site#56, Brussels, , Belgium
Exelixis Clinical Site #30, Brussels, , Belgium
Exelixis Clinical Site #47, Edegem, , Belgium
Exelixis Clinical Site #38, Gent, , Belgium
Exelixis Clinical Site#87, Paris, Ile-de-France, France
Exelixis Clinical Site#69, Lyon, Rhone-Alpes, France
Exelixis Clinical Site #45, Bordeaux, , France
Exelixis Clinical Site #41, Pierre Benite, , France
Exelixis Clinical Site#68, Poitiers, , France
Exelixis Clinical Site #50, Rennes, , France
Exelixis Clinical Site#63, Strasbourg, , France
Exelixis Clinical Site#53, Villejuif, , France
Exelixis Clinical Site#62, Milano, MI, Italy
Exelixis Clinical Site #54, Ancona, , Italy
Exelixis Clinical Site#60, Firenze, , Italy
Exelixis Clinical Site#84, Milan, , Italy
Exelixis Clinical Site #40, Roma, , Italy
Exelixis Clinical Site#90, Roma, , Italy
Exelixis Clinical Site #34, Rozzano, , Italy
Exelixis Clinical Site#61, Siena, , Italy
Exelixis Clinical Site#79, Anyang-si, Gyeonggi-do, Korea, Republic of
Exelixis Clinical Site#80, Seongnam-si, Gyeonggi-Do, Korea, Republic of
Exelixis Clinical Site#74, Seongnam-si, Gyeonggido [Kyonggi-do], Korea, Republic of
Exelixis Clinical Site#83, Suwon, Gyeonggido [Kyonggi-do], Korea, Republic of
Exelixis Clinical Site#86, Busan, Gyeongsangnam-do, Korea, Republic of
Exelixis Clinical Site#78, Hwasun, Jeonranamdo [Chollanam-do], Korea, Republic of
Exelixis Clinical Site#77, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], Korea, Republic of
Exelixis Clinical Site#81, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], Korea, Republic of
Exelixis Clinical Site#85, Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], Korea, Republic of
Exelixis Clinical Site#73, Amsterdam, Noord-Holland, Netherlands
Exelixis Clinical Site#76, Rotterdam, Zuid-Holland, Netherlands
Exelixis Clinical Site#65, Groningen, , Netherlands
Exelixis Clinical Site #39, Maastricht, , Netherlands
Exelixis Clinical Site #27, Barcelona, , Spain
Exelixis Clinical Site #36, Barcelona, , Spain
Exelixis Clinical Site#55, Barcelona, , Spain
Exelixis Clinical Site#82, Barcelona, , Spain
Exelixis Clinical Site #31, Lleida, , Spain
Exelixis Clinical Site#64, Madrid, , Spain
Exelixis Clinical Site #17, Madrid, , Spain
Exelixis Clinical Site #33, Madrid, , Spain
Exelixis Clinical Site #42, Madrid, , Spain
Exelixis Clinical Site #13, Madrid, , Spain
Exelixis Clinical Site #46, Málaga, , Spain
Exelixis Clinical Site #43, Valencia, , Spain
Exelixis Clinical Site #51, Valencia, , Spain
Exelixis Clinical Site#72, Zaragoza, , Spain
Exelixis Clinical Site#88, Leicester, England, United Kingdom
Exelixis Clinical Site#89, London, England, United Kingdom
Exelixis Clinical Site#91, Cardiff, Wales, United Kingdom
Exelixis Clinical Site #52, Glasgow, , United Kingdom
Exelixis Clinical Site#57, London, , United Kingdom
Exelixis Clinical Site #28, Newcastle Upon Tyne, , United Kingdom
Contact Details
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