Spots Global Cancer Trial Database for Immune Boost In Non-Small Cell Lung Cancer
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Trial Identification
Brief Title: Immune Boost In Non-Small Cell Lung Cancer
Official Title: A Randomized Phase II Study of Radiation Induced Immune Boost in Operable Non-small Cell Lung Cancer
Study ID: NCT02319408
Conditions
Interventions
Study Description
Brief Summary: Insufficient migration and activation of tumour specific effector T cells seems to be the one important reason for inadequate host anti-tumour immune response. Ionizing radiation can induce a variety of immune responses. The goal of this randomized trial is to assess if a preoperative single fraction low dose radiation is able to improve anti-tumour immune response in operable early stage lung cancer.
Detailed Description:
Keywords
Eligibility
Minimum Age: 50 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Thoracic Surgery, Thoraxklinik, University Hospital Heidelberg, Heidelberg, , Germany
German Cancer Research Centre and Clinic for Radiation Oncology of the University of Heidelberg, Heidelberg, , Germany
Contact Details
Name: Seyer Safi, MD, PhD
Affiliation: University Hospital Heidelberg
Role: PRINCIPAL_INVESTIGATOR
Name: Hans Hoffmann, MD, PhD
Affiliation: University Hospital Heidelberg
Role: PRINCIPAL_INVESTIGATOR
Name: Peter Huber, MD, PhD
Affiliation: German Cancer Research Centre
Role: PRINCIPAL_INVESTIGATOR
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