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Brief Title: Erlotinib vs. Standard Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) and Eastern Cooperative Oncology Group (ECOG)Performance Status (PS) 2
Official Title: A Randomized Phase II Study of Single Agent Erlotinib [Tarceva (TM), OSI-774] Versus Standard Chemotherapy in Patients With Previously Untreated Advanced NSCLC and a Poor Performance Status
Study ID: NCT00085839
Brief Summary: The purpose of this noncomparative study is to obtain preliminary estimates of the efficacy of erlotinib and standard chemotherapy in patients with advanced, previously untreated nonsmall cell lung cancer (NSCLC) and an Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 2. The study will also evaluate the safety of single-agent erlotinib in this patient population.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
California Cancer Care, Inc., Greenbrae, California, United States
Sharp Clinical Oncology Research, San Diego, California, United States
Holy Cross Hospital, Fort Lauderdale, Florida, United States
Mount Sinai Cancer Center, Miami Beach, Florida, United States
University of Miami, Miami, Florida, United States
Evanston Northwestern Healthcare, Evanston, Illinois, United States
Oncology/Hematology Associates of Central Illinois, Peoria, Illinois, United States
Norton Healthcare, Inc., Louisville, Kentucky, United States
Maryland Hematology/Oncology Associates, Baltimore, Maryland, United States
VA Sierra Nevada Health Care System, Reno, Nevada, United States
Weill Medical College of Cornell University, New York, New York, United States
FEK Addo, PC, Bismarck, North Dakota, United States
Gabrail Cancer Center, Canton, Ohio, United States
University Hospitals of Cleveland, Cleveland, Ohio, United States
Ohio State University, Columbus, Ohio, United States
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
Charleston Hematology Oncology, Charleston, South Carolina, United States
East Tennessee Oncology/Hematology, PC, Knoxville, Tennessee, United States
Sarah Cannon Cancer Center, Nashville, Tennessee, United States