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Brief Title: A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors
Official Title: A Phase 2, Open-label, Single-arm, Multicenter Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced/Refractory Solid Tumors
Study ID: NCT05256381
Brief Summary: The primary objective of the study is to estimate the antitumor efficacy of nanrilkefusp alfa in combination with pembrolizumab in selected tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Innovative Clinical Research Institute, Whittier, California, United States
University of Pittsburg Medical Center (UPMC) Hillman Cancer Center, Pittsburgh, Pennsylvania, United States
Institut Jules Bordet, Anderlecht, , Belgium
Cliniques Universitaires Saint-Luc, Brussels, , Belgium
Grand Hospital de Charleroi, Charleroi, , Belgium
Universitair Ziekenhuis Leuven - Campus Gasthuisberg, Leuven, , Belgium
Centre Hospitalier Universitaire de Liège, Liège, , Belgium
Masarykuv Onkologicky Ustav, Brno, , Czechia
Nemocnice Hořovice, Hořovice, , Czechia
Fakultní nemocnice Olomouc, Olomouc, , Czechia
Hôpital Ambroise-Paré, Boulogne-Billancourt, , France
Merchant Logo Institute Bergonié, Bourdeaux, , France
Centre de Lutte Contre le Cancer, Caen, , France
Hospital del la Timone, Marseille, , France
Centre Hospitalier Universitaire de Nantes, Nantes, , France
Centre Antoine Lacassagne, Nice, , France
Hospital L'archet, Nice, , France
Hôpital Foch, Suresnes, , France
Institute Claudius Regaud, Toulouse, , France
Gustave Roussy, Villejuif, , France
High Technology Hospital MedCenter Ltd - Batumi, Batumi, , Georgia
Evex Hospitals- Kutaisi Referral, Kutaisi, , Georgia
LLC Todua Clinic, Tbilisi, , Georgia
Evex Hospitals - Caraps Medline, Tbilisi, , Georgia
New Vision University Hospital, Tbilisi, , Georgia
Tbilisi Institute of Medicine, Tbilisi, , Georgia
Jerarsi Clinic, Tbilisi, , Georgia
Consilium Medulla Multiprofile Clinic, Tbilisi, , Georgia
Evex Hospitals - Caucasus Medical Center, Tbilisi, , Georgia
Észak-Pesti Centrumkórház - Honvédkórház, Budapest, , Hungary
Petz Aladár Egyetemi Oktató Kórház - Győr, Győr, , Hungary
Azienda Socio Sanitaria Territoriale (ASST) degli Spedali Civili di Brescia, Brescia, , Italy
Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST, Meldola, , Italy
Instituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, , Italy
Ospedale Guglielmo da Saliceto, Piacenza, , Italy
Fondazione Policlinico Universitario Agostino Gemelli, Rome, , Italy
Azienda Ospedaliera Universitaria Senese - L'ospedale Santa Maria alle Scotte, Siena, , Italy
Ospedale Civile di Sondrio, Sondrio, , Italy
Azienda Ospedaliera Universitaria Integrata Verona, Verona, , Italy
Uniwersytecki Szpital Kliniczny w Poznaniu, Poznań, Wielkopolskie, Poland
Pratia Poznań, Skorzewo, , Poland
MTZ Clinical Research powered by Pratia, Warszawa, , Poland
Hospital Teresa Herrera - Materno Infantil, A Coruña, , Spain
Hospital Germans Trias i Pujol, Badalona, , Spain
Hospital Universitari Vall d'Hebrón, Barcelona, , Spain
Institut Catala d'Oncologia, Barcelona, , Spain
Clinica Universidad de Navarra - Pamplona, Madrid, , Spain
Clínica Universidad de Navarra - Madrid, Madrid, , Spain
Hospital Universitario 12 de Octubre, Madrid, , Spain
Hospital Universitario HM Sanchinarro, Madrid, , Spain
Hospital Universitario Puerta de Hierro - Majadahonda, Madrid, , Spain
Hospital Clínico Universitario de Valencia, Valencia, , Spain