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Brief Title: Carboplatin, Pemetrexed, and Panitumumab in Patients With Advanced Non-Squamous K-ras Wild Type NSCLC
Official Title: A Phase II Trial of Carboplatin, Pemetrexed, and Panitumumab in Patients With Advanced Non-Squamous K-ras Wild Type Non-Small-Cell Lung Cancer
Study ID: NCT01042288
Brief Summary: The purpose of this multicenter, Phase II trial is to examine the role of a well-tolerated novel agent, panitumumab, in combination with a modern platinum doublet regimen using carboplatin and pemetrexed, in patients with advanced non-squamous wild type K-ras non-small-cell lung cancer (NSCLC). If this treatment proves to be well tolerated and associated with efficacy, this would provide rationale for further randomized studies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Florida Cancer Specialists, Ft. Myers, Florida, United States
Florida Hospital Cancer Institute, Orlando, Florida, United States
Medical Oncology Associates of Augusta, Augusta, Georgia, United States
Northeast Georgia Medical Center, Gainesville, Georgia, United States
Baptist Hospital East, Louisville, Kentucky, United States
Norton Cancer Institute, Louisville, Kentucky, United States
Center for Cancer and Blood Disorders, Bethesda, Maryland, United States
National Capital Clinical Research Consortium, Bethesda, Maryland, United States
Portsmouth Regional Hospital, Portsmouth, New Hampshire, United States
Oncology Hematology Care, Cincinnati, Ohio, United States
Cancer Centers of Southwest Oklahoma, Lawton, Oklahoma, United States
Tennessee Oncology, PLLC, Nashville, Tennessee, United States
Peninsula Cancer Institute, Newport News, Virginia, United States
Name: David R Spigel, MD
Affiliation: SCRI Development Innovations, LLC
Role: STUDY_CHAIR