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Brief Title: A Study of Mapatumumab in Combination With Paclitaxel and Carboplatin in Subjects With Non-small Cell Lung Cancer
Official Title: A Phase 2, Randomized, Multi-Center, Open-Label Study to Evaluate the Efficacy and Safety of Mapatumumab in Combination With Carboplatin and Paclitaxel as First Line Therapy in Subjects With Advanced Non-Small Cell Lung Cancer (NSCLC)
Study ID: NCT00583830
Brief Summary: The purpose of this study is to evaluate the efficacy (disease response) and safety of mapatumumab in combination with carboplatin and paclitaxel as first line therapy in subjects with advanced non-small cell lung cancer (NSCLC).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Birmingham Hematology and Oncology Associates, LLC, Birmingham, Alabama, United States
Desert Hematology Oncology Medical Group, Inc., Rancho Mirage, California, United States
University of Colorado Health Sciences Center, Aurora, Colorado, United States
Osceola Cancer Center, Kissimmee, Florida, United States
Palm Beach Cancer Institute, West Palm Beach, Florida, United States
Rush University Medical Center, Chicago, Illinois, United States
LaGrange Oncology Associates, LaGrange, Illinois, United States
Orchard Research, LLC, Skokie, Illinois, United States
Kentuckiana Cancer Institute, PLLC, Louisville, Kentucky, United States
University of Maryland, Greenebaum Cancer Center, Baltimore, Maryland, United States
Chevy Chase Health Care, Chevy Chase, Maryland, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Medical University of South Carolina: Hollings Cancer Center, Charleston, South Carolina, United States
The Sarah Cannon Cancer Center, Nashville, Tennessee, United States
UT Health Science Center at San Antonio, Be Well Center, San Antonio, Texas, United States
Fairfax-Northern Virginia Hematology Oncology, PC, Fairfax, Virginia, United States
Charite - Campus Mitte, Universitätsmedizin Berlin, Abteilung Onkologie und Hämatologie, Berlin, , Germany
Universitätsmedizin Berlin, Centrum für Innere Medizin, Berlin, , Germany
Asklepios Fachkliniken München-Gauting, Gauting, , Germany
Krankenhaus Großhansdorf, Großhansdorf, , Germany
Krankenhaus Martha-Maria Halle-Dölau, Halle, , Germany
Universitätsklinik Magdeburg, Klinik für Kardiologie, Angiologie und Pneumologie, Magdeburg, , Germany
Klinikum der Johannes-Gutenberg-Universität Mainz, Mainz, , Germany
Universitätsklinikum Mannheim, Chirurgische Klinik, Mannheim, , Germany
Pius-Hospital, Oldenburg, , Germany
Paracelsus Klinik, Zentrum für Tumordiagnostik und -therapie, Osnabrück, , Germany
Fővárosi Önkormányzat Uzsoki Utcai Kórház, Budapest, , Hungary
Országos Korányi TBC és Pulmonológiai Intezet, Budapest, , Hungary
Debrecen University, Medical and Health Center, Dept of Oncology, Debrecen, , Hungary
Kenézy Gyula Kórház, Debrecen, Pulmonológia, Debrecen, , Hungary
Institutul Oncologic 'Prof Dr. Al Trestioreanu' Bucuresti, Bucuresti, , Romania
Institutul Oncologic 'Prof . Dr. I. Chiricuta' Cluj-Napoca, Cluj-Napoca, , Romania
Spitalul Clinic Judetean Oradea, Oncology Department, Oradea, , Romania
Name: GSK Clinical Trials
Affiliation: GlaxoSmithKline
Role: STUDY_DIRECTOR