Spots Global Cancer Trial Database for A Prospective Cohort Study to Evaluate Molecular pRognostic Factors and Resistance Mechanisms to Osimertinib in Adjuvant Treatment of Completely Resected pIB-IIIA Non-small Cell Lung Carcinoma With Common EGFR Mutations (L858R and Del19)
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Trial Identification
Brief Title: A Prospective Cohort Study to Evaluate Molecular pRognostic Factors and Resistance Mechanisms to Osimertinib in Adjuvant Treatment of Completely Resected pIB-IIIA Non-small Cell Lung Carcinoma With Common EGFR Mutations (L858R and Del19)
Official Title: A Prospective Cohort Study to Evaluate Molecular pRognostic Factors and Resistance Mechanisms to Osimertinib in Adjuvant Treatment of Completely Resected pIB-IIIA Non-small Cell Lung Carcinoma With Common EGFR Mutations (L858R and Del19)
Study ID: NCT06053099
Study Description
Brief Summary: IFCT-2202 ROSIE study aims to incorporate a broad-panel centralized NGS testing at baseline in all patients with completely resected NSCLC with common EGFR mutation after confirmation of an optimal preoperative extension assessment and with a centralized review of the quality of the surgical excision. Furthermore, the IFCT-2202 ROSIE study also aims to study the molecular events associated with relapse on, or after osimertinib exposure, that should result in the opportunity to accede to optimal treatment in case of metastatic relapse.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Angers - CHU, Angers, , France
Bayonne - CH, Bayonne, , France
Boulogne - Ambroise Paré, Boulogne, , France
Lyon - URCOT, Bron, , France
Caen - CHU, Caen, , France
Clermont-Ferrand - CHU, Clermont-Ferrand, , France
Colmar - CH, Colmar, , France
Créteil - CHI, Créteil, , France
Dijon - CHU Bocage, Dijon, , France
Grenoble - CHU, Grenoble, , France
La Roche-Sur-Yon - CH, La Roche-sur-Yon, , France
Le Mans - CHG, Le Mans, , France
Lille - CHU, Lille, , France
Lyon - CRLCC, Lyon, , France
Marseille - APHM, Marseille, , France
Metz - Hôpital Robert Schuman, Metz, , France
Montpellier - CHU, Montpellier, , France
Montpellier - ICM, Montpellier, , France
Nice - CHU, Nice, , France
Orléans - CHR, Orléans, , France
Paris - Bichat, Paris, , France
Paris - HEGP, Paris, , France
Paris - Hôpital Cochin, Paris, , France
Paris - Pitié-Salpêtrière, Paris, , France
Paris - Tenon, Paris, , France
Pau - CHG, Pau, , France
Bordeaux - CHU, Pessac, , France
Poitiers - CHU, Poitiers, , France
Annecy - CH, Pringy, , France
Rennes - CHU, Rennes, , France
Rouen - CHU, Rouen, , France
Strasbourg - NHC, Strasbourg, , France
Suresnes - Foch, Suresnes, , France
Toulon - CHI, Toulon, , France
Toulouse - CHU, Toulouse, , France
Tours - CHU, Tours, , France
Contact Details
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