Spots Global Cancer Trial Database for Effect of Exercise Training on Angiogenesis and Cachexia in Lung Cancer Patients
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Trial Identification
Brief Title: Effect of Exercise Training on Angiogenesis and Cachexia in Lung Cancer Patients
Official Title: Effect of Exercise Training on Angiogenesis and Cachexia in Lung Cancer Patients
Study ID: NCT01136083
Conditions
Study Description
Brief Summary: Cancer is one of the leading health issues in this country and worldwide. Angiogenesis is an essential process for tumoral growth and metastasis. This process is dependent on the balance between angiogenic factors and antiangiogenic factors. Muscle wasting has been associated with myostatin overexpression in cancer. Exercise training can depress tumor growth and suppress myostatin expression, and enhance skeletal muscle angiogenesis in healthy people and some animal studies. The purpose of this study is mainly to investigate the effects of exercise training on 1. circulating VEGF-A 2. muscle growth and function 3. Myostatin
Detailed Description:
Eligibility
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
National Taiwan University Hospital, Taipei City, , Taiwan
Contact Details
Name: Ying-Tai Wu, Ph.D
Affiliation: National Taiwan University Hospital
Role: PRINCIPAL_INVESTIGATOR
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