Spots Global Cancer Trial Database for A Study of Relatlimab Plus Nivolumab in Combination With Chemotherapy vs. Nivolumab in Combination With Chemotherapy as First Line Treatment for Participants With Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)
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Trial Identification
Brief Title: A Study of Relatlimab Plus Nivolumab in Combination With Chemotherapy vs. Nivolumab in Combination With Chemotherapy as First Line Treatment for Participants With Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)
Official Title: A Phase 2 Randomized Study of Relatlimab Plus Nivolumab in Combination With Chemotherapy vs. Nivolumab in Combination With Chemotherapy as First Line Treatment for Participants With Stage IV or Recurrent Non-small Cell Lung Cancer (NSCLC)
Study ID: NCT04623775
Study Description
Brief Summary: The purpose of this study is to assess the safety profile of relatlimab plus nivolumab in combination with platinum doublet chemotherapy (PDCT) and to determine if nivolumab plus relatlimab in combination with PDCT improves overall response rate (ORR) when compared to nivolumab plus PDCT in participants with previously untreated Stage IV or recurrent non-small cell lung cancer (NSCLC).
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Local Institution - 0160, Duarte, California, United States
Local Institution - 0081, Orange, California, United States
Local Institution - 0139, New Haven, Connecticut, United States
Local Institution - 0153, Jacksonville, Florida, United States
Local Institution - 0011, Port Saint Lucie, Florida, United States
Local Institution - 0089, Athens, Georgia, United States
Local Institution - 0121, Wichita, Kansas, United States
Local Institution - 0159, Lexington, Kentucky, United States
Local Institution - 0002, Louisville, Kentucky, United States
Local Institution - 0082, Scarborough, Maine, United States
Local Institution - 0129, Omaha, Nebraska, United States
Local Institution - 0152, Howell, New Jersey, United States
Local Institution - 0097, Bronx, New York, United States
Local Institution - 0124, Johnson City, New York, United States
Local Institution - 0162, Mineola, New York, United States
Local Institution - 0128, New York, New York, United States
Local Institution - 0165, New York, New York, United States
Local Institution - 0117, Durham, North Carolina, United States
Local Institution - 0156, Cincinnati, Ohio, United States
Local Institution - 0155, Cleveland, Ohio, United States
Local Institution - 0084, Lancaster, Pennsylvania, United States
Local Institution - 0147, Pittsburgh, Pennsylvania, United States
Local Institution - 0148, Providence, Rhode Island, United States
Local Institution - 0083, Greenville, South Carolina, United States
Local Institution - 0149, Dallas, Texas, United States
Local Institution - 0091, Harlingen, Texas, United States
Local Institution - 0001, Tyler, Texas, United States
Local Institution - 0092, Spokane, Washington, United States
Local Institution - 0157, Morgantown, West Virginia, United States
Local Institution - 0037, Rio Cuarto, Cordoba, Argentina
Local Institution - 0021, Buenos Aires, Distrito Federal, Argentina
Local Institution - 0014, Caba, Distrito Federal, Argentina
Local Institution - 0073, Capital, LA Rioja, Argentina
Local Institution - 0039, Viedma, RIO Negro, Argentina
Local Institution - 0029, Rosario, Santa Fe, Argentina
Local Institution - 0060, Cordoba, , Argentina
Local Institution - 0038, Cordoba, , Argentina
Local Institution - 0055, Camperdown, New South Wales, Australia
Local Institution - 0086, Gosford, New South Wales, Australia
Local Institution - 0132, Tamworth, New South Wales, Australia
Local Institution - 0057, South Brisbane, Queensland, Australia
Local Institution - 0130, Ballarat, Victoria, Australia
Local Institution - 0138, Bendigo, Victoria, Australia
Local Institution - 0141, Box Hill, Victoria, Australia
Local Institution - 0109, Frankston, Victoria, Australia
Local Institution - 0119, Murdoch, Western Australia, Australia
Local Institution - 0085, Nedlands, Western Australia, Australia
Local Institution - 0090, Graz, , Austria
Local Institution - 0126, Vienna, , Austria
Local Institution - 0125, Roeselare, West-Vlaanderen, Belgium
Local Institution - 0127, Ghent, , Belgium
Local Institution - 0131, Ghent, , Belgium
Local Institution - 0063, Natal, Rio Grande Do Norte, Brazil
Local Institution - 0161, Ijui, Rio Grande Do Sul, Brazil
Local Institution - 0116, Porto Alegre, RIO Grande DO SUL, Brazil
Local Institution - 0112, Porto Alegre, RIO Grande DO SUL, Brazil
Local Institution - 0107, Barretos, Sao Paulo, Brazil
Local Institution - 0111, Santo Andre, SAO Paulo, Brazil
Local Institution - 0072, Rio de Janeiro, , Brazil
Local Institution - 0163, Sao Paulo, , Brazil
Local Institution - 0120, Sao Paulo, , Brazil
Local Institution - 0041, Santiago, Metropolitana, Chile
Local Institution - 0016, Santiago, Metropolitana, Chile
Local Institution - 0079, Santiago, Metropolitana, Chile
Local Institution - 0008, Rennes, Ille-Et-Vilaine, France
Local Institution - 0007, Dijon cedex, , France
Local Institution - 0144, Le Mans, , France
Local Institution - 0110, Paris, , France
Local Institution - 0102, Paris, , France
Local Institution - 0035, Paris, , France
Local Institution - 0006, Saint-Mande, , France
Local Institution - 0103, Berlin, , Germany
Local Institution - 0045, Berlin, , Germany
Local Institution - 0065, Essen, , Germany
Local Institution - 0062, Grosshansdorf, , Germany
Local Institution - 0058, Homburg, , Germany
Local Institution - 0108, Lowenstein, , Germany
Local Institution - 0071, Marburg, , Germany
Local Institution - 0050, Paderborn, , Germany
Local Institution - 0030, Ravensburg, , Germany
Local Institution - 0133, Dublin, , Ireland
Local Institution - 0023, Dublin, , Ireland
Local Institution - 0106, Rome, RA, Italy
Local Institution - 0028, Candiolo, , Italy
Local Institution - 0009, Catania, , Italy
Local Institution - 0032, Genova Sampierdarena, , Italy
Local Institution - 0059, Milano, , Italy
Local Institution - 0164, Pesaro, , Italy
Local Institution - 0019, Siena, , Italy
Local Institution - 0070, Ciudad de Mexico, Distrito Federal, Mexico
Local Institution - 0020, Toluca de Lerdo, Estado DE Mexico, Mexico
Local Institution - 0115, Monterrey, Nuevo LEON, Mexico
Local Institution - 0013, San Pedro Garza Garcia, Nuevo LEON, Mexico
Local Institution - 0158, Arnhem, , Netherlands
Local Institution - 0053, Harderwijk, , Netherlands
Local Institution - 0145, Gdynia, , Poland
Local Institution - 0036, Lublin, , Poland
Local Institution - 0031, Lublin, , Poland
Local Institution - 0080, Olsztyn, , Poland
Local Institution - 0088, Warszawa, , Poland
Local Institution - 0099, Cluj Napoca, Cluj, Romania
Local Institution - 0017, Craiova, Dolj, Romania
Local Institution - 0052, Craiova, Jud. DOLJ, Romania
Local Institution - 0069, Timisoara, Timis, Romania
Local Institution, Craiova, , Romania
Arkhangelsk Clinical Oncological Dispensary, Arkhangelsk, , Russian Federation
FSBI ",Research Institute of Influenza named after A.A. Smorodintsev ",of the MoH of the Rus, Saint Petersburg, , Russian Federation
LLC Eurocityclinic, Saint-Petersburg, , Russian Federation
Local Institution - 0042, Malaga, Andalucia, Spain
Local Institution - 0075, Sevilla, Andalucia, Spain
Local Institution - 0137, Badalona, Barcelona, Spain
Local Institution - 0061, Las Palmas de Gran Canaria, Las Palmas, Spain
Local Institution - 0051, A Coruna, , Spain
Local Institution - 0154, Barcelona, , Spain
Local Institution - 0048, Barcelona, , Spain
Local Institution - 0024, Barcelona, , Spain
Local Institution - 0074, Madrid, , Spain
Local Institution - 0123, Madrid, , Spain
Local Institution - 0043, Valencia, , Spain
Local Institution - 0015, Basel, , Switzerland
Local Institution - 0104, St. Gallen, , Switzerland
Local Institution - 0135, Middlesborough, Cleveland, United Kingdom
Local Institution - 0101, London, Greater London, United Kingdom
Local Institution - 0095, Manchester, Lancashire, United Kingdom
Local Institution - 0067, Leicester, , United Kingdom
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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