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Spots Global Cancer Trial Database for A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

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Trial Identification

Brief Title: A Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)

Official Title: A Phase I-III, Multicenter Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Patients Selected According to Biomarker Status, With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer

Study ID: NCT05170204

Study Description

Brief Summary: This study will evaluate the efficacy and safety of multiple therapies in participants with locally advanced, unresectable, Stage III NSCLC with eligible biomarker status as determined by Version 8 of the American Joint Committee on Cancer/Union for International Cancer Control NSCLC staging system.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Southern California Kaiser Permanente, San Diego, California, United States

Rocky Mountain Cancer Centers - Lone Tree, Lone Tree, Colorado, United States

Mount Sinai Medical Center; Comprehensive Cancer Center, Miami Beach, Florida, United States

University Of Michigan, Ann Arbor, Michigan, United States

Oregon Health Sciences Uni, Portland, Oregon, United States

Northwest Cancer Specialists, P.C., Tigard, Oregon, United States

Hillman Cancer Center;Medical Oncology, Pittsburgh, Pennsylvania, United States

Thompson Cancer Survival Center, Knoxville, Tennessee, United States

Baptist Cancer Center, Memphis, Tennessee, United States

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Mays Cancer Center, UT Health San Antonio, San Antonio, Texas, United States

Virginia Cancer Specialists (Fairfax) - USOR, Fairfax, Virginia, United States

Lifehouse, Camperdown, New South Wales, Australia

Northern Cancer Institute, St Leonards, New South Wales, Australia

Westmead Hospital; Medical Oncology and Pallative Care, Westmead, New South Wales, Australia

Peter MacCallum Cancer Centre; Medical Oncology, Melbourne, Victoria, Australia

One Clinical Research, Nedlands, Western Australia, Australia

GHdC Site Notre Dame, Charleroi, , Belgium

UZ Gent, Gent, , Belgium

Hospital Sao Rafael - HSR, Salvador, BA, Brazil

Crio - Centro Regional Integrado de Oncologia, Fortaleza, CE, Brazil

Oncocentro Belo Horizonte, Belo Horizonte, MG, Brazil

COT - Centro Oncologico do Triangulo, Uberlandia, MG, Brazil

Oncoclinicas Rio de Janeiro S.A., Rio de Janeiro, RJ, Brazil

Santa Casa de Misericordia de Porto Alegre, Porto Alegre, RS, Brazil

Hospital Nossa Senhora da Conceicao, Porto Alegre, RS, Brazil

Clínica de Oncologia Reichow, Blumenau, SC, Brazil

Hospital de Cancer de Barretos, Barretos, SP, Brazil

Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, SP, Brazil

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

Centro de Estudios Clínicos SAGA, Santiago, , Chile

OrlandiOncología, Santiago, , Chile

James Lind Centro de Investigación Del Cáncer, Temuco, , Chile

Beijing Cancer Hospital, Beijing, , China

Hunan Cancer Hospital, Changsha CITY, , China

Hunan Cancer Hospital, Changsha CITY, , China

Xinqiao Hospital of Third Military Medical University, Chongqing City, , China

Shandong Cancer Hospital, Jinan, , China

Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing City, , China

The affiliated hospital of Qingdao university, Qingdao City, , China

Shanghai Pulmonary Hospital, Shanghai, , China

Tianjin Medical University Cancer Institute & Hospital, Tianjin, , China

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan City, , China

Shanxi Cancer Hospital, Xi'an, , China

Clinica De La Costa, Barranquilla, , Colombia

Fundación CTIC - Centro de Tratamiento e Investigación sobre Cáncer Luis Carlos Sarmiento Angulo, Bogota, D.C., , Colombia

Hospital Universitario San Ignacio, Bogota, , Colombia

Fundacion Cardioinfantil, Bogota, , Colombia

Instituto Cancerologia Medellin; Clinica Las Americas, Medellin, , Colombia

Clinica CIMCA, San José, , Costa Rica

ICIMED Instituto de Investigación en Ciencias Médicas, San José, , Costa Rica

CHU Angers,Service de Pneumologie, Angers, , France

Centre Leon Berard, Lyon, , France

Hopital Nord; Pneumologie, Marseille cedex 20, , France

Hôpitaux D'Instruction Des Armees Begin, St Mande, , France

Hia Sainte Anne; Pneumologie, Toulon, , France

CHU de Toulouse - Hôpital Larrey, Toulouse, , France

Helios Klinikum Emil von Behring GmbH, Berlin, , Germany

Klinikum Chemnitz gGmbH, Chemnitz, , Germany

Klinikum Esslingen; Klinik für Kardiologie, Angiologie und Pneumologie, Esslingen, , Germany

Thoraxklinik Heidelberg gGmbH, Heidelberg, , Germany

LMU Klinikum der Universität München, Medizinische Klinik und Poliklinik V, Campus Innenstadt, München, , Germany

Universitätsklinikum Regensburg; Klinik und Poliklinik für Innere Medizin II, Pneumologie, Regensburg, , Germany

Queen Mary Hospital; Dept. of Clinical Oncology, Hong Kong, , Hong Kong

Rambam Medical Center; Oncology, Haifa, , Israel

Rabin Medical Center-Beilinson Campus; Davidof Institute, Petach Tikva, , Israel

IRST Istituto Scientifico Romagnolo Per Lo Studio E Cura Dei Tumori, Sede Meldola; Oncologia Medica, Meldola, Emilia-Romagna, Italy

Azienda Ospedaliera San Camillo Forlanini; U.O.C. Pneumologia Ad Indirizzo Oncologico 1, Roma, Lazio, Italy

IRCCS A.O.U San MArtino - IST; U.O. Oncologia Medica 2, Genova, Liguria, Italy

ASST DEGLI SPEDALI CIVILI DI BRESCIA; Oncologia Medica, Brescia, Lombardia, Italy

Irccs Istituto Europeo di Oncologia (IEO); Divisione di Oncologia, Milano, Lombardia, Italy

Asst Grande Ospedale Metropolitano Niguarda; Dipartimento Di Ematologia Ed Oncologia, Milano, Lombardia, Italy

A.O. UNIVERSITARIA S. LUIGI GONZAGA; Oncologia Medica, Orbassano, Piemonte, Italy

Azienda Ospedaliero-Universitaria Careggi; SOD Radioterapia, Firenze, Toscana, Italy

IRCCS Istituto Oncologico Veneto (IOV); Oncologia Medica Seconda, Padova, Veneto, Italy

Ospedale P. Pederzoli Casa di cura Privata; Lung Unit Thoracic 3° Floor, Peschiera Del Garda (VR), Veneto, Italy

Aichi Cancer Center Hospital, Aichi, , Japan

Hirosaki University Hospital, Aomori, , Japan

National Cancer Center East, Chiba, , Japan

Shikoku Cancer Center, Ehime, , Japan

NHO Kyushu Cancer Center, Fukuoka, , Japan

Kurume University Hospital, Fukuoka, , Japan

Kobe City Medical Center General Hospital, Hyogo, , Japan

National Hospital Organization Himeji Medical Center, Hyogo, , Japan

Kagoshima University Hospital, Kagoshima, , Japan

Kanagawa Cancer Center, Kanagawa, , Japan

Kumamoto University Hospital, Kumamoto, , Japan

Sendai Kousei Hospital, Miyagi, , Japan

Nara Medical University Hospital, Nara, , Japan

Niigata Cancer Center Hospital, Niigata, , Japan

Okayama University Hospital, Okayama, , Japan

Kurashiki Central Hospital, Okayama, , Japan

Kindai University Hospital ; Faculty of Medicine, Osaka-sayama, , Japan

Osaka City General Hospital, Osaka, , Japan

Osaka International Cancer Institute, Osaka, , Japan

NHO Kinki Chuo Chest Medical Center, Osaka, , Japan

Shizuoka Cancer Center, Shizuoka, , Japan

Juntendo University Hospital, Tokyo, , Japan

Komagome Hospital, Tokyo, , Japan

The Cancer Institute Hospital of JFCR, Tokyo, , Japan

Tottori University Hospital, Tottori, , Japan

National Hospital Organization Yamaguchi - Ube Medical Center, Yamaguchi, , Japan

Chungbuk National University Hospital, Cheongju si, , Korea, Republic of

Kyungpook National University Chilgok Hospital, Daegu, , Korea, Republic of

Pusan National University Yangsan Hospital, Gyeongsangnam-do, , Korea, Republic of

Chonnam National University Hwasun Hospital, Jeollanam-do, , Korea, Republic of

Seoul National University Bundang Hospital, Seongnam-si, , Korea, Republic of

Kangbuk Samsung Hospital, Seoul, , Korea, Republic of

Asan Medical Center, Seoul, , Korea, Republic of

Korea University Guro Hospital, Seoul, , Korea, Republic of

Auckland City Hospital, Cancer and Blood Research, Auckland, , New Zealand

Oslo universitetssykehus HF, Ullevål, Kreftsenteret, Oslo, , Norway

Instytut Genetyki i Immunologii GENIM, Lublin, , Poland

Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie; Oddzial onkologii z pododdzialem chemioterapii, Olsztyn, , Poland

Wielkopolskie Centrum Pulmonologii i Torakochirurgii w Poznaniu, Poznan, , Poland

Narod.Inst.Onkol. im. M.Sklodowskiej - Curie-Panst.Inst.Bad; Klinika Nowot.Pluca i Klatki Piers, Warszawa, , Poland

Dolno?l?skie Centrum Chorób P?uc we Wroc?awiu; Oddzia? Onkologii Klinicznej VII, Wroc?aw, , Poland

University Clinical Centre of Serbia; Clinic for Pulmonology, Belgrade, , Serbia

Hospital Medical Center Bezanijska kosa; Clinic for Medical Oncology, Belgrade, , Serbia

Univ Clinical Center Kragujevac; Clinic for Pulmonology, Kragujevac, , Serbia

Institute for Pulmonary Diseases of Vojvodina; Clinic for Pulmonary Oncology, Sremska Kamenica, , Serbia

National Cancer Centre; Medical Oncology, Singapore, , Singapore

Tan Tock Seng Hospital; Oncology, Singapore, , Singapore

Complejo Hospitalario Universitario A Coruña (CHUAC); Servicio de Oncologia, A Coruña, LA Coruña, Spain

Complejo Hospitalario Universitario Insular?Materno Infantil; Servicio de Oncologia, Las Palmas de Gran Canaria, LAS Palmas, Spain

Hospital General Univ. de Alicante; Servicio de Oncologia, Alicante, , Spain

Hospital Universitari Vall d'Hebron; Oncology, Barcelona, , Spain

Hospital Ramon y Cajal; Servicio de Oncologia, Madrid, , Spain

Hospital Universitario 12 de Octubre; Servicio de Oncologia, Madrid, , Spain

Hospital Universitario La Paz; Servicio de Oncologia, Madrid, , Spain

Hospital Regional Universitario Carlos Haya; Servicio de Oncologia, Malaga, , Spain

Hospital Universitario Virgen del Rocio; Servicio de Oncologia, Sevilla, , Spain

Hospital Clínico Universitario de Valencia; Servicio de Oncología, Valencia, , Spain

Sahlgrenska University Hospital; Sahlgrenska Clinical Trial unit / Department of Oncology, Göteborg, , Sweden

Karolinska Universitetssjukhuset, Solna; Kliniska prövningsenheten Z:4:01, Stockholm, , Sweden

Taipei Medical University ?Shuang Ho Hospital, New Taipei City, , Taiwan

National Cheng Kung Univ Hosp, Tainan, , Taiwan

National Taiwan Uni Hospital, Taipei City, , Taiwan

Taipei Veterans General Hospital, Taipei City, , Taiwan

Taipei Medical University Hospital, Taipei, , Taiwan

Taipei Municipal Wan Fang Hospital, Taipei, , Taiwan

Chang Gung Memorial Hospital - Linkou, Taoyuan, , Taiwan

Taichung Veterans General Hospital, Xitun Dist., , Taiwan

Rajavithi Hospital; Division of Medical Oncology, Bangkok, , Thailand

Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology, Bangkok, , Thailand

Oncology Unit, Faculty of Medicine, Vajira Hospital; Department of Medicine, Dusit, , Thailand

Songklanagarind Hospital; Department of Internal Medicine, Division of Respiratory, Songkhla, , Thailand

Baskent University Adana Dr. Turgut Noyan Practice and Research Hospital; Medical Oncology, Adana, , Turkey

Gazi Uni Medical Faculty Hospital; Oncology Dept, Ankara, , Turkey

Liv Hospital Ankara; Medical Oncology, Ankara, , Turkey

Bakirkoy Dr. Sadi Konuk Egitim ve Arastirma Hastanesi, Tibbi Onkoloji, Bakirkoy / Istanbul, , Turkey

Ataturk University Medical Faculty Yakutiye Research Hospital Medical Oncology Department, Erzurum, , Turkey

Medipol University Medical Faculty; Oncology Department, Istanbul, , Turkey

Istanbul Uni Cerrahpasa Medical Faculty Hospital; Medical Oncology, Istanbul, , Turkey

Marmara Uni Faculty of Medicine; Medical Oncology, Istanbul, , Turkey

Medikal Park Samsun, Samsun, , Turkey

Birmingham Heartlands Hospital, Birmingham, , United Kingdom

Velindre Cancer Centre; Oncology Dept, Cardiff, , United Kingdom

Barts & London School of Med; Medical Oncology, London, , United Kingdom

Royal Marsden Hospital; Dept of Med-Onc, London, , United Kingdom

Christie Hospital Nhs Trust; Medical Oncology, Manchester, , United Kingdom

Contact Details

Name: Clinical Trials

Affiliation: Hoffmann-La Roche

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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