Spots Global Cancer Trial Database for Optimization of Treatment of Advanced Nonsmall Cell Lung Cancer Using Radiotherapy and Chemotherapy
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Trial Identification
Brief Title: Optimization of Treatment of Advanced Nonsmall Cell Lung Cancer Using Radiotherapy and Chemotherapy
Official Title: Optimization of Treatment of Advanced Nonsmall Cell Lung Cancer Using Radiotherapy and Chemotherapy
Study ID: NCT00864331
Conditions
Study Description
Brief Summary: Primary objectives of the study are: To assess the differences in survival of the two treatment options in both stage III (A and B) nonsmall cell lung cancer (NSCLC) (Study A) and Stage IIIB (wet) and stage IV NSCLC (Study B), respectively Secondary objectives are: To assess the differences in toxicity of two treatment options in both stage III (A and B) NSCLC (Study A) and Stage IIIB (wet) and stage IV NSCLC (Study B), and To assess the differences in Health Related Quality of Life (HRQoL) of two treatment options in both Study A and Study B
Detailed Description: To compare survival rates (median and 1-year), and toxicity of two treatment regimens in patients with locally advanced incurable NSCLC (study A), to compare survival rates (median and 1-year) of two treatment regimens in patients with locally advanced and metastatic NSCLC (study B) To compare HRQoL and cost effectiveness of two treatment regimens in patients with locally advanced incurable NSCLC (study A), and in patients with locally advanced and metastatic NSCLC (study B) and to evaluate the effect of HRQoL assessment on QoL dimensions
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Instituto de Radiomedicine, Santiago, , Chile
Affiliated Hospital of Ning Xia Medical College, Department of Radiation Oncology, Yinchuan, , China
University of Zagreb Faculty of Medicine, Zagreb, , Croatia
Misr Oncology Center (MOC), Cairo, , Egypt
Tata Memorial Centre (TMC) Department of Atomic Energy (DAE), Mumbai, , India
General Hospital Kuala Lumpur, Institute of Radiotherapy and Oncology, Kuala Lumpur, , Malaysia
Sir Paul Boffa Hospital, Floriana, , Malta
Ministère de la Santé, Institut National d'Oncologie Sidi Mohamed Ben Abdellah, Rabat, , Morocco
Nuclear Medicine Oncology and Radiotherapy Institute, Islamabad, , Pakistan
Instituto Oncológico National, Panama City, , Panama
Instituto Nacional de Enfermadades Neoplasicas Depto. De Radioterapia, Lima, , Peru
University of Witwatersrand Johannesburg Hospital Dept of Radiation Oncology, Johannesburg, , South Africa
Institut de la Sante Publique, Institut National de Cancer Salah Azaiz, Tunis, , Tunisia
Contact Details
Name: Elena Fidarova, MD
Affiliation: International Atomic Energy Agency
Role: PRINCIPAL_INVESTIGATOR
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