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Brief Title: Prospective Multicenter Observational Study of Atezolizumab Combination Therapy in Lung Cancer (J-TAIL-2)
Official Title: Prospective Multicenter Observational Study of Atezolizumab Combination Therapy in Patients With Unresectable, Advanced and Recurrent Non-small Cell Lung Cancer or Extensive Disease Small Cell Lung Cancer
Study ID: NCT04501497
Brief Summary: This is a multi-center observational study of atezolizumab combination therapy in patients with unresectable, advanced and recurrent non-small cell lung cancer(NSCLC) or extensive disease small cell lung cancer(ED-SCLC). 800 patients in NSCLC cohort and 400 patients in ED-SCLC cohort will be enrolled in this trial to assess the efficacy and safety of this combination.
Detailed Description: Primary endpoint: 12 months OS, Secondary endpoints: Overall Survival(OS), 6 months survival rate(6mo OS), 12 months survival rate(12mo OS), Progression-Free Survival(PFS), Time to treatment failure (TTF), Objective Response Rate(ORR), Disease Control Rate(DCR), Duration of Response(DOR) ,Safety and Comprehensive geriatric assessment(G8)
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Akashi Medical Center, Akashi, , Japan
Hyogo Cancer Center, Akashi, , Japan
Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, , Japan
Asahikawa Medical University Hospital, Asahikawa, , Japan
National Hospital Organization Asahikawa Medical Center, Asahikawa, , Japan
Juntendo University Hospital, Bunkyō-Ku, , Japan
Nippon Medical School Hospital, Bunkyō-Ku, , Japan
Tokyo Medical And Dental University, Medical Hospital, Bunkyō-Ku, , Japan
Chiba University Hospital, Chiba, , Japan
National Cancer Center Hospital, Chuo Ku, , Japan
Fujisawa City Hospital, Fujisawa, , Japan
Fukui Prefectural Hospital, Fukui, , Japan
Fukuoka University Hospital, Fukuoka, , Japan
Kyushu University Hospital, Fukuoka, , Japan
National Hospital Organization Kyushu Cancer Center, Fukuoka, , Japan
National Hospital Organization Kyushu Medical Center, Fukuoka, , Japan
Fukushima Medical University Hospital, Fukushima, , Japan
Gifu Prefectural General Medical Center, Gifu, , Japan
National Hospital Organization Okinawa National Hospital, Ginowan, , Japan
Hamamatsu University Hospital, Hamamatsu, , Japan
National Hospital Organization Himeji Medical Center, Himeji, , Japan
Kansai Medical University Hospital, Hirakata, , Japan
Hirosaki University Hospital, Hirosaki, , Japan
Hiroshima City Hiroshima Citizens Hospital, Hiroshima, , Japan
Hiroshima Prefectural Hospital, Hiroshima, , Japan
Hiroshima University Hospital, Hiroshima, , Japan
Aso Iizuka Hospital, Iizuka, , Japan
Nippon Medical School Chiba Hokusoh Hospital, Inzai, , Japan
Tokai University Hospital, Isehara, , Japan
Japanese Red Cross Ise Hospital, Ise, , Japan
Teikyo University Hospital, Itabashi-Ku, , Japan
Itami City Hospital, Itami, , Japan
National Hospital Organization Iwakuni Clinical Center, Iwakuni, , Japan
Shimane University Hospital, Izumo, , Japan
Juntendo University Shizuoka Hospital, Izunokuni, , Japan
Kagawa University Hospital, Kagawa, , Japan
Kagoshima University Hospital, Kagoshima, , Japan
Kameda Medical Center, Kamogawa, , Japan
Ishikawa Prefectural Central Hospital, Kanazawa, , Japan
Kanazawa University Hospital, Kanazawa, , Japan
Ibaraki Prefectural Central Hospital, Kasama, , Japan
Kasukabe Medical Center, Kasukabe, , Japan
Kishiwada City Hospital, Kishiwada, , Japan
Hospital of the University of Occupational and Envioronmental Health, Kitakyushu, , Japan
Japan Community Health care Organization Kyushu Hospital, Kitakyushu, , Japan
Kitakyushu Municipal Medical Center, Kitakyushu, , Japan
Japan Anti-Tuberculosis Association Fukujuji Hospital, Kiyose, , Japan
National Hospital Organization Tokyo National Hospital, Kiyose, , Japan
Kobe City Medical Center General Hospital, Kobe, , Japan
Kobe Minimally Invasive Cancer Center, Kobe, , Japan
Kobe University Hospital, Kobe, , Japan
Dokkyo Medical University Saitama Medical Center, Koshigaya, , Japan
The Cancer Institute Hospital of Japanese Foundation For Cancer Research, Koto-Ku, , Japan
Kurashiki Central Hospital, Kurashiki, , Japan
National Hospital Organization Kure Medical Center and Chugoku Cancer, Kure, , Japan
Kurume University Hospital, Kurume, , Japan
Kyoto City Hospital, Kyoto, , Japan
Kyoto University Hospital, Kyoto, , Japan
Kyoto-Katsura Hospital, Kyoto, , Japan
National Hospital Organization Kyoto Medical Center, Kyoto, , Japan
University Hospital, Kyoto Prefectural University of Medicine, Kyoto, , Japan
Shinshu University Hospital, Matsumoto, , Japan
Matsusaka Municipal Hospital, Matsusaka, , Japan
National Hospital Organization Shikoku Cancer Center, Matsuyama, , Japan
National Hospital Organization Tokyo Medical Center, Meguro-Ku, , Japan
The Jikei University Hospital, Minato-Ku, , Japan
Tokyo Saiseikai Central Hospital, Minato-Ku, , Japan
Kyorin University Hospital, Mitaka, , Japan
Miyazaki Prefectural Miyazaki Hospital, Miyazaki, , Japan
Nagahama City Hospital, Nagahama, , Japan
Aichi Medical University Hospital, Nagakute, , Japan
Nagasaki University Hospital, Nagasaki, , Japan
Aichi Cancer Center, Nagoya, , Japan
Japanese Red Cross Nagoya Daini Hospital, Nagoya, , Japan
Nagoya City University Hospital, Nagoya, , Japan
Nagoya Ekisaikai Hospital, Nagoya, , Japan
Nagoya University Hospital, Nagoya, , Japan
National Hospital Organization Nagoya Medical Center, Nagoya, , Japan
Miyagi Cancer Center, Natori, , Japan
Niigata Cancer Center Hospital, Niigata, , Japan
Niigata University Medical and Dental Hospital, Niigata, , Japan
The Hospital of Hyogo College of Medicine, Nishinomiya, , Japan
Obihiro Kosei Hospital, Obihiro, , Japan
Japanese Red Cross Okayama Hospital, Okayama, , Japan
Kawasaki Medical School General Medical Center, Okayama, , Japan
Okayama Rosai Hospital, Okayama, , Japan
Okayama University Hospital, Okayama, , Japan
Osaka City General Hospital, Osaka, , Japan
Osaka General Medical Center, Osaka, , Japan
Osaka International Cancer Institute, Osaka, , Japan
Osaka Saiseikai Nakatsu Hospital, Osaka, , Japan
Osaki Citizen Hospital, Osaki, , Japan
Kitasato University Hospital, Sagamihara, , Japan
Saga University Hospital, Saga, , Japan
Jichi Medical University Saitama Medical Center, Saitama, , Japan
Saitama medical university International medical Center, Saitama, , Japan
Saitama Prefectural Cancer Center, Saitama, , Japan
Saitama Red Cross Hospital, Saitama, , Japan
National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai, , Japan
Hokkaido University Hospital, Sapporo, , Japan
National Hospital Organization Hokkaido Cancer Center, Sapporo, , Japan
Sapporo Medical University Hospital, Sapporo, , Japan
Teine Keijinkai Hospital, Sapporo, , Japan
Sendai Kousei Hospital, Sendai, , Japan
Tohoku Medical And Pharmaceutical University Hospital, Sendai, , Japan
Tohoku University Hospital, Sendai, , Japan
Japanese Red Cross Medical Center, Shibuya-Ku, , Japan
Jichi Medical University Hospital, Shimotsuke, , Japan
Showa University Hospital, Shinagawa-Ku, , Japan
Center Hospital of the National Center for Global Health and Medicine, Shinjuku-Ku, , Japan
Keio University Hospital, Shinjuku-Ku, , Japan
Tokyo Medical University Hospital, Shinjuku-Ku, , Japan
Iwate Medical University Hospital, Shiwa-gun, , Japan
Shizuoka Cancer Center, Shizuoka, , Japan
Shizuoka General Hospital, Shizuoka, , Japan
Osaka University Hospital, Suita, , Japan
Saiseikai Suita Hospital, Suita, , Japan
Kagawa Prefectural Central Hospital, Takamatsu, , Japan
JA Toyama Kouseiren Takaoka Hospital, Takaoka, , Japan
Takarazuka City Hospital, Takarazuka, , Japan
Osaka Medical and Pharmaceutical University Hospital, Takatsuki, , Japan
Tenri Hospital, Tenri, , Japan
Dokkyo Medical University Hospital, Tochigi, , Japan
Tokushima Prefectural Central Hospital, Tokushima, , Japan
Tokushima University Hospital, Tokushima, , Japan
Toyama Prefectural Central Hospital, Toyama, , Japan
Fujita Health University Hospital, Toyoake, , Japan
National Hospital Organization Osaka Toneyama Medical Center, Toyonaka, , Japan
TOYOTA Memorial Hospital, Toyota, , Japan
Tsukuba Medical Center Hospital, Tsukuba, , Japan
University of Tsukuba Hospital, Tsukuba, , Japan
Ehime University Hospital, Tōon, , Japan
National Hospital Organization Yamaguchi-Ube Medical Center, Ube, , Japan
Juntendo University Urayasu Hospital, Urayasu, , Japan
Japanese Red Cross Wakayama Medical Center, Wakayama, , Japan
Wakayama Medical University Hospital, Wakayama, , Japan
Kanagawa Cancer Center, Yokohama, , Japan
Kanagawa Cardiovascular and Respiratory Center, Yokohama, , Japan
Yokohama City University Hospital, Yokohama, , Japan
Yokohama Municipal Citizen's Hospital, Yokohama, , Japan
Yokosuka Kyosai Hospital, Yokosuka, , Japan
Tottori University Hospital, Yonago, , Japan
Oita University Hospital, Yufu, , Japan
Ogaki Municipal Hospital, Ōgaki, , Japan
Oita Prefectural Hospital, Ōita, , Japan
Kindai University Hospital, Ōsaka-sayama, , Japan
Gunma Prefectural Cancer Center, Ōta, , Japan
Shiga University of Medical Science Hospital, Ōtsu, , Japan
Name: Akihiko GENMA
Affiliation: Nippon Medical School Hospital
Role: PRINCIPAL_INVESTIGATOR