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Brief Title: Study of TQB2450 Combined With Anlotinib in Patients With Advanced Non-small Cell Lung Cancer(NSCLC)
Official Title: A Phase Ib, Multicenter, Randomized Study to Evaluate the Pharmacokinetics, Efficacy and Safety of TQB2450 Combined With or Without Anlotinib in Patients With Advanced Non-small Cell Lung Cancer(NSCLC)
Study ID: NCT03910127
Brief Summary: TQB2450 is a humanized monoclonal antibody targeting programmed death ligand-1 (PD-L1), which prevents PD-L1 from binding to PD-1 and B7.1 receptors on T cell surface, restores T cell activity, thus enhancing immune response and has potential to treat various types of tumors.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Gansu Province Tumor Hospital, Lanzhou, Gansu, China
Henan Province Tumor Hospital, Luoyan, Henan, China
Jilin Cancer Hospital, Changchun, Jilin, China
Name: Baohui Han, Doctor
Affiliation: Shanghai Chest Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Kai Li, Doctor
Affiliation: Tianjin Cancer Hospital
Role: PRINCIPAL_INVESTIGATOR