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Brief Title: A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF)
Official Title: A PHASE 2, OPEN LABEL STUDY TO EVALUATE SAFETY AND CLINICAL ACTIVITY OF AVELUMAB (BAVENCIO (REGISTERED)) IN COMBINATION WITH AXITINIB (INLYTA (REGISTERED)) IN PATIENTS WITH ADVANCED OR METASTATIC PREVIOUSLY TREATED NON-SMALL CELL LUNG CANCER OR TREATMENT NAÏVE CISPLATIN-INELIGIBLE UROTHELIAL CANCER JAVELIN MEDLEY VEGF
Study ID: NCT03472560
Brief Summary: This is a Phase 2 study to evaluate the safety and efficacy of avelumab in combination with axitinib in patients with advanced or metastatic non-small cell lung cancer (NSCLC) who have received at least one prior platinum containing therapy, and in treatment naïve patients with advanced or metastatic urothelial cancer, who are ineligible for cisplatin containing chemotherapy for their advanced disease.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Arizona Oncology Associates- Saguaro Cancer Center, Glendale, Arizona, United States
Arizona Oncology Associates, Goodyear, Arizona, United States
Arizona Oncology Associates- Biltmore Cancer Center, Phoenix, Arizona, United States
Arizona Oncology Associates- Deer Valley Cancer Center, Phoenix, Arizona, United States
Arizona Oncology Associates- East Valley Cancer Center, Tempe, Arizona, United States
The Oncology Institute of Hope and Innovation, Glendale, California, United States
The Oncology Institute of Hope and Innovation, Long Beach, California, United States
The Oncology Institute of Hope and Innovation, Santa Ana, California, United States
The Oncology Institute of Hope and Innovation, Whittier, California, United States
Oncology Hematology Associates, Springfield, Missouri, United States
Oncology Hematology West, PC dba Nebraska Cancer Specialists, Omaha, Nebraska, United States
Oncology Hematology West, PC dba Nebraska Cancer Specialists, Omaha, Nebraska, United States
Saint Francis Hospital, Greenville, South Carolina, United States
Saint Francis Hospital Cancer Center, Greenville, South Carolina, United States
Bacs-Kiskun Megyei Korhaz Onkoradiologiai Kozpont, Kecskemet, , Hungary
Pecsi Tudomanyegyetem Klinikai Kozpont, Pecs, , Hungary
Tudogyogyintezet Torokbalint, Torokbalint, , Hungary
Azienda Ospedaliero Universitaria Policlinico Umberto I, Roma, , Italy
Cardiologia - Azienda Ospedaliero Universitaria Policlinico Umberto I, Roma, , Italy
Farmacia Azienda Ospedaliero Universitaria Policlinico Umberto I, Roma, , Italy
UOC di Radiologia - Azienda Ospedaliero Universitaria Policlinico Umberto I, Roma, , Italy
National Cancer Center, Goyang-si, Gyeonggi-do, Korea, Republic of
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
Samsung Medical Center, Gangnam-gu, Seoul, Korea, Republic of
Asan Medical Center, Songpa-gu, Seoul, Korea, Republic of
Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie, Warszawa, Mazowieckie, Poland
Regionalny Szpital Specjalistyczny Im. Dr. Wladyslawa Bieganskiego w Grudziadzu, Grudziadz, , Poland
Centrum Medyczne Dom Lekarski S.A., Szczecin, , Poland
Centrum Onkologii Instytut im. Marii Sklodowskiej-Curie w Warszawie, Warszawa, , Poland
GBUZ of Stavropol Territory "Pyatigorsk Inter-regional Oncology Dispanser", Pyatigorsk, Stavropol Territory, Russian Federation
LLC "University clinic of headache", Moscow, , Russian Federation
Limited Liability Company "VitaMed" (LLC "VitaMed"), Moscow, , Russian Federation
LLC "University Clinic of Headache", Moscow, , Russian Federation
Limited Liability Company "VitaMed" (LLC "VitaMed"), Moscow, , Russian Federation
Instituto Catalan de Oncologia, Hospitalet de Llobregat, Barcelona, Spain
Consorcio Hospitalario Provincial de Castellon, Castellon, , Spain
Chi Mei Hospital, Liouying, Tainan City, Liouying District, Taiwan
National Cheng Kung University Hospital, Tainan, , Taiwan
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR