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Brief Title: A Study of Mycobacterium w in Combination With Paclitaxel Plus Cisplatin in Advanced Non Small Cell Lung Cancer
Official Title: Open Label, Randomized Multicentric Phase II Clinical Trial of Mycobacterium w in Combination With Paclitaxel Plus Cisplatin Versus Paclitaxel and Cisplatin in Advanced Non Small Cell Lung Cancer.
Study ID: NCT00680940
Brief Summary: The purpose of this study is to determine whether Mycobacterium w in combination with Paclitaxel plus Cisplatin are effective in Advanced Non Small Cell Lung cancer.
Detailed Description: Non-small cell lung cancer (NSCLC) accounts for 75% of all lung cancers. majority of patients of NSCLC patients are stage IIIA or IIIB patients are suitable for radiotherapy, which could not improve the survival rates of 5-10%. This study proposed Mycobacterium w (heat killed) in combination chemotherapy of Cisplatin and Paclitaxel along with radiotherapy for adjuvant therapy management of NSCLC in controlled clinical trial, which may prove the efficacy, better survival rate and quality of life.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Gujarat Cancer & Research Institute, New Civil Hospital Campus, Asarwa, Ahmedabad, India
Regional Cancer Center, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
MNJ Institute of Oncology, Regional Cancer Centre, Red Hills, Hyderabad, India
Malabar Institute of Medical Science (MIMS), Calicut, Kerala, India
B.P. Poddar Hospital and Medical Research Ltd., New Alipore, Kolkata, India
Choithram Hospital and Research Centre, Indore, Madhya Pradesh, India
Regional Cancer Centre, Indira Gandhi Institute of Medical Science, Sheikhpura, Patna, India
Patel Hospital Pvt. Ltd, Jalandhar, Punjab, India
Acharya Tulsi Regional Cancer Treatment & Research Institute, Bikaner, Rajasthan, India
V.N. Cancer Center, GKNM Hospital, Coimbatore, TamilNadu, India
Netaji Subash Chandra Bose Cancer Research Institute, Kolkata, West Bangal, India
Bankura Sammilani Medical College, Gobindnagar, West Bengal, India
Institute of Post Graduate Medical education & Research, Kolkata, West Bengal, India
Chittaranjan National Cancer Institute, Kolkata, West Bengal, India
Name: R K Chaudhary, MD
Affiliation: Acharya Tulsi Regional Cancer Treatment & Research Institute
Role: PRINCIPAL_INVESTIGATOR
Name: Rajeev Gupta, MD
Affiliation: Patel Hospital Pvt. Ltd.
Role: PRINCIPAL_INVESTIGATOR
Name: Anup Majumdar, MD
Affiliation: Institute of Post Graduate Medical Education & Research
Role: PRINCIPAL_INVESTIGATOR
Name: A. Rajkumar, MD
Affiliation: V.N. Cancer Center GKNM Hospital
Role: PRINCIPAL_INVESTIGATOR
Name: Rajeev Seam, MD
Affiliation: Regional Cancer center, Indira Gandhi Medical College
Role: PRINCIPAL_INVESTIGATOR
Name: A.K. Patel, MD
Affiliation: Choithram Hospital and Research Centre
Role: PRINCIPAL_INVESTIGATOR
Name: Chanchal Goswami, MD
Affiliation: B.P.Poddar Hospital and Medical Research Ltd.
Role: PRINCIPAL_INVESTIGATOR
Name: Jaydip Biswas, MD
Affiliation: Chittaranjan National Cancer Institute
Role: PRINCIPAL_INVESTIGATOR
Name: Ritwik Pandyea, MD
Affiliation: Netaji Subhash Chandra Bose Cancer Research Institute
Role: PRINCIPAL_INVESTIGATOR
Name: Aloke G Dastidar, MD
Affiliation: Bankura Sammilani Medical College
Role: PRINCIPAL_INVESTIGATOR
Name: Narayanankutty Warrier, MD
Affiliation: Malabar Institute of Medical Science (MIMS)
Role: PRINCIPAL_INVESTIGATOR
Name: Ashutosh N Aggarwal, MD
Affiliation: Post Graduate Institute of Medical Education and Research, Chandigarh
Role: PRINCIPAL_INVESTIGATOR
Name: Apurva Patel, MD
Affiliation: Gujarat Cancer & Research Institute
Role: PRINCIPAL_INVESTIGATOR
Name: Santanu Chaudhary, MD
Affiliation: R.S.T. Cancer Hospital & Research Centre
Role: PRINCIPAL_INVESTIGATOR
Name: Rajeev Prasad, MD
Affiliation: Regional Cancer Centre, Indira Ghandhi Institute of Medical Science
Role: PRINCIPAL_INVESTIGATOR
Name: Ramakrishna Malladi, MD
Affiliation: MNJ Institute of Oncology, Regional Cancer Centre
Role: PRINCIPAL_INVESTIGATOR