⭐️⭐️⭐️⭐️⭐️ "A total no brainer"

⭐️⭐️⭐️⭐️⭐️ "Love this, so easy."

Spots is the easy way to track your skin, mole and cancer changes.

Spots Global Cancer Trial Database for Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05)

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05)

Official Title: Phase 2, Single-arm, Open-label Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations and Progressed On or After Applicable Targeted Therapy and Platinum Based Chemotherapy (TROPION-Lung05)

Study ID: NCT04484142

Interventions

DS-1062a

Study Description

Brief Summary: This is a study of the efficacy, pharmacokinetics, and safety of DS-1062a in participants with advanced or metastatic non-small cell lung cancer (NSCLC) with known actionable genomic alterations.

Detailed Description: This study will evaluate DS-1062a 6.0 mg/kg in participants with advanced or metastatic NSCLC with actionable genomic alterations and who have been previously been treated with 1 platinum-containing therapy and 1 or more lines of targeted therapy. The study will be divided into 3 periods: Screening Period, Treatment Period, and Follow-up Period. The primary analysis of Objective Response Rate (ORR) by blinded Independent Central Review (BICR) will be conducted after all participants either have been followed for at least 9 months after the start of study treatment or have discontinued from the study, whichever occurs first.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Mayo Clinic, Phoenix, Arizona, United States

University of California San Diego, La Jolla, California, United States

UCLA, Santa Monica, California, United States

Boca Raton Regional Hospital, Boca Raton, Florida, United States

Sarah Cannon Research Institute at Florida Cancer Center, North, Gainesville, Florida, United States

Mayo Clinic, Jacksonville, Florida, United States

AdventHealth Orlando, Orlando, Florida, United States

Sarah Cannon Research Institute at Florida Cancer Center, South, Port Charlotte, Florida, United States

Moffitt Cancer Center, Tampa, Florida, United States

The Office of Dr. Frederick P. Smith MD, Chevy Chase, Maryland, United States

Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States

Dana Farber Cancer Institute, Boston, Massachusetts, United States

University of Michigan, Detroit, Michigan, United States

Mayo Clinic, Rochester, Minnesota, United States

Washington University School of Medicine, Saint Louis, Missouri, United States

XCancer / Regional Cancer Care Associate (Astera), East Brunswick, New Jersey, United States

NYU Langone Medical Center, New York, New York, United States

Weill Cornell Medical College, New York, New York, United States

New York Cancer and Blood Specialists, Port Jefferson, New York, United States

University Hospitals Case Medical Center, Cleveland, Ohio, United States

Avera Cancer Institute Sioux Falls, Sioux Falls, South Dakota, United States

Sarah Cannon Research Institute at Tennessee Oncology - Chattanooga, Chattanooga, Tennessee, United States

Sarah Cannon Research Institute, Nashville, Tennessee, United States

Mary Crowley Cancer Research, Dallas, Texas, United States

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Virginia Cancer Specialists, Athens, Virginia, United States

Kadlec Clinic Hematology and Oncology, Kennewick, Washington, United States

Seattle Cancer Care Alliance, Seattle, Washington, United States

APHM - Hopital Nord, Marseille Cedex 20, Bouches-Du-Rhône, France

Gustav Roussy Cancer Campus Grand Paris, Villejuif, ile-de-France, France

University Hospital of Nantes, Nantes, Loire-Atlantique, France

CHU Toulouse Hopital Larrey, Toulouse, Occitanie, France

Centre Leon Berard, Lyon, Rhone, France

CHU Louis Pradel, Lyon, , France

Institut Curie, Paris, , France

Hopitaux Universitaire de Strasbourg- Nouvel Hopital Civil, Strasbourg, , France

Centre Hospitalier Intercommunal Toulon La Seyne sur mer Hopital Sainte-Musse, Toulon, , France

Thoraxklinik Heidelberg, Heidelberg, Baden-Württemberg, Germany

Asklepios Fachklinik Muenchen-Gauting, Gauting, Bayern, Germany

IKF Krankenhaus Nordwest, Frankfurt Am Main, Hessen, Germany

Universitaet zu Koeln - Uniklinik Koeln, Koeln, North Rhine-Westphal, Germany

Medizinische Hochschule Hannover, Hannover, , Germany

Thoraxklinik Heidelberg gGmbH, Heidelberg, , Germany

National Koranyi Institute for TB and Pulmonology, Budapest, , Hungary

Pulmonology Hospital Törökbálint, Torokbalint, , Hungary

Azienda Ospedaliera Universitaria Policlinico-OVE, Catania, CT, Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, RM, Italy

University of Turin San Luigi Hospital, Orbassano, Torino, Italy

Azienda Ospedaliero-Universitaria S. Orsola Malpighi, Bologna, , Italy

Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, , Italy

Istituto Europeo di Oncologia, Milano, , Italy

Azienda Ospedaliero Universitaria di Parma, Parma, , Italy

Azienda Ospedaliera Arcispedale Santa Maria, Reggio Emilia, , Italy

Fujita Health University Hospital, Toyoake-shi, Aichi, Japan

National Cancer Center Hospital East, Kashiwa-shi, Chiba, Japan

Hokkaido Cancer Center, Sapporo-shi, Hokkaido, Japan

Kyoto University Hospital, Kyoto-shi, Kyoto, Japan

Niigata Cancer Center Hospital, Niigata-shi, Niigata, Japan

Kansai Medical University Hospital, Hirakata-shi, Osaka, Japan

Osaka City General Hospital, Osaka-shi, Osaka, Japan

Osaka International Cancer Institute, Osaka-shi, Osaka, Japan

Kindai University Hospital, Ōsaka-sayama, Osaka, Japan

Shizuoka Cancer Center, Nagaizumi-chō, Shizuoka, Japan

Tokushima University Hospital, Tokushima-shi, Tokushima, Japan

National Cancer Center Hospital, Chuo Ku, Tokyo, Japan

The Cancer Institute Hospital of JFCR, Koto-Ku, Tokyo, Japan

Aichi Cancer Center Hospital, Aichi, , Japan

Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do, Korea, Republic of

Seoul National University Hospital, Seoul, , Korea, Republic of

Severance Hospital, Seoul, , Korea, Republic of

Asan Medical Center, Seoul, , Korea, Republic of

Samsung Medical Center, Seoul, , Korea, Republic of

The Netherlands Cancer Institute, Amsterdam, North Holland, Netherlands

Erasmus MC, Rotterdam, Zuid Holland, Netherlands

Hospital Universitario Puerta de Hierro de Majadahonda, Majadahonda, Madrid, Spain

Hospital Regional Universitario Malaga, Málaga, Malaga, Spain

Hospital General Universitario de Alicante, Alicante, , Spain

Hospital Universitario Vall dHebron, Barcelona, , Spain

Hospital Clinic i Provincial de Barcelona, Barcelona, , Spain

Hospital Universitario 12 de Octubre, Madrid, , Spain

National Cheng Kung University Hospital, Tainan, , Taiwan

Taipei Veterans General Hospital, Taipei City, , Taiwan

National Taiwan University Hospital NTUH, Taipei, , Taiwan

Koo Foundation Sun Yat-Sen Cancer Center, Taipei, , Taiwan

Contact Details

Name: Global Clinical Leader

Affiliation: Daiichi Sankyo

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

Logo

Take Control of Your Skin and Body Changes Today.

Try out Spots for free, set up only takes 2 mins.

spots app storespots app store

Join others from around the world: