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Brief Title: A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy Regimen
Official Title: A Randomized Phase 2 Trial Of Pf-00299804 Versus Erlotinib For The Treatment Of Advanced Non-small Cell Lung Cancer After Failure Of At Least One Prior Chemotherapy Regimen
Study ID: NCT00769067
Brief Summary: This study will compare PF-00299804 given orally on continuous schedule to the approved drug, erlotinib, in patients whose non-small cell lung cancer has progressed after chemotherapy; patients will be randomized to receive one of these drugs, and followed for efficacy and tolerance of each.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Northwest Alabama Cancer Center, Muscle Shoals, Alabama, United States
Agajanian Institute of Oncology and Hematology, Montebello, California, United States
Bridgeport Hospital, Bridgeport, Connecticut, United States
Wittingham Cancer Center @ Norwalk Hospital, Norwalk, Connecticut, United States
Medical Oncology & Hematology, P.C., Waterbury, Connecticut, United States
Winship Cancer Institute at Grady Health Systems, Atlanta, Georgia, United States
Winship Cancer Institute, Emory University, Atlanta, Georgia, United States
Winship Cancer Institute at Emory University, Atlanta, Georgia, United States
Winship Cancer Institute of Emory University, Atlanta, Georgia, United States
Winship Cancer Institute, Emory University, Atlanta, Georgia, United States
Augusta Oncology Associates, P.C., Augusta, Georgia, United States
Augusta Oncology Associates, PC, Augusta, Georgia, United States
John B. Amos Cancer Center, Columbus, Georgia, United States
Georgia Cancer Specialists, Decatur, Georgia, United States
The Longstreet Cancer Center, Gainesville, Georgia, United States
Central Georgia Cancer Care, P.C., Macon, Georgia, United States
Northwest Georgia Oncology Center, Marietta, Georgia, United States
Central Georgia Cancer Care, P.C., Warner Robins, Georgia, United States
Kootenai Cancer Center at Post Falls, Post Falls, Idaho, United States
Kootenai Cancer Center, Post Falls, Idaho, United States
Midwestern Regional Medical Center, Zion, Illinois, United States
Center for Blood and Cancer Disorders, Bethesda, Maryland, United States
Associates in Oncology/Hematology, PC, Rockville, Maryland, United States
University of Minnesota Cancer Center, Minneapolis, Minnesota, United States
The West Clinic, Memphis, Tennessee, United States
Oncology/Hematology Associates, Clarksburg, West Virginia, United States
Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia
St. Vincent's Hospital, Fitzroy, Victoria, Australia
The Andrew Love Cancer Centre,, Geelong, Victoria, Australia
Border Medical Oncology, Wodonga, Victoria, Australia
Irmandade da Santa Casa de Misericordia de Porto Alegre (ISCMPA) - Hospital Santa Rita, Porto Alegre, RS, Brazil
Hospital Sao Lucas da PUCRS, Porto Alegre, RS, Brazil
FUNDACAO PIO XII Hospital de Cancer de Barretos, Barretos, SP, Brazil
Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira - ICESP, Sao Paulo, SP, Brazil
BC Cancer Agency - Vancouver Centre, Vancouver, British Columbia, Canada
Royal Victoria Hospital, Barrie, Ontario, Canada
RSM Durham Regional Cancer Centre - Lakeridge Health Oshawa, Oshawa, Ontario, Canada
The Ottawa Hospital Cancer Centre, Ottawa, Ontario, Canada
Department of Clinical Oncology, Shatin, New Territories, Hong Kong
Department of Clinical Oncology, Tuen Mun Hospital, Tuen Mun, New Territories, Hong Kong
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Yonsei University College of Medicine, Yonsei Cancer Center, Seoul, , Korea, Republic of
SamsungMedicalCenter,SungkyunkwanUnivSchoolofMedicine,Div. of Hematology-Oncology, Dep. of Medicine, Seoul, , Korea, Republic of
Medex spolka cywilna, Chrzanow, , Poland
¿KardioDent¿, Krakow, , Poland
"Vesalius" Sp. z o.o., Krakow, , Poland
Zaklad Rentgena i USG Wyrobek spolka jawna, Krakow, , Poland
Centrum Onkologii-Instytut im. Marii Sklodowskiej-Curie, Warsaw, , Poland
Niepubliczny Zaklad Opieki Zdrowotnej AVI Centrum Medyczne, Warszawa, , Poland
Ponce School of Medicine / CAIMED Center, Ponce, , Puerto Rico
National Cancer Centre, Singapore, , Singapore
Hospital Universitari Germans Trias I Pujol, Badalona, Barcelona, Spain
Hospital Son Llatzer, Palma de Mallorca, Islas Baleares, Spain
Hospital de Cruces, Barakaldo, Vizcaya, Spain
Hospital Teresa Herrera, La Coruña, , Spain
National Taiwan University Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Chest Department, Taipei, , Taiwan
Christie Hospital NHS Foundation Trust, Manchester, , United Kingdom
Churchill Hospital, Oxford, , United Kingdom
Name: Pfizer CT.gov Call Center
Affiliation: Pfizer
Role: STUDY_DIRECTOR