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Brief Title: Cancer Vaccine Study for Stage III, Unresectable, Non-small Cell Lung Cancer (NSCLC) in the Asian Population
Official Title: A Multi-national, Double-blind, Placebo-controlled, Randomized, Phase III Clinical Trial of the Cancer Vaccine Stimuvax® (L-BLP25 or BLP25 Liposome Vaccine) in Asian Subjects With Stage III, Unresectable, Non-small Cell Lung Cancer (NSCLC) Who Have Demonstrated Either Stable Disease or Objective Response Following Primary Chemo-radiotherapy
Study ID: NCT01015443
Brief Summary: The purpose of this study is to determine whether the cancer vaccine tecemotide (L-BLP25) in addition to best supportive care is effective in prolonging the lives of Asian subjects with unresectable stage III non-small cell lung cancer in comparison to a placebo plus best supportive care (a so-called placebo controlled study).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
307 Hospital of Chinese PLA, Beijing, , China
Beijing Cancer Hospital, Beijing, , China
Beijing Chest Hospital, Beijing, , China
Cancer Institue & Hospital, Chinese Academy of Medical Sciences, Beijing, , China
The First Hospital of Jilin University, ChangChun, , China
Jillin Provincial Cancer Hospital, Changchun, , China
West China Hospital of Sichuan University, Chengdu, Sichuan Province, , China
Southwest Hospital of the Third Military Medical University, Chongqing, , China
The Second Affiliate Hospital of the Third Military Medical University, Chongqing, , China
Fujian Province Tumor Hospital, Fuzhou, , China
Guangdong General Hospital, GuangZhou, , China
The First Affilated Hospital of Guangzhou Medical College, Guangzhou, , China
Heilongjiang Cancer Hospital, Haerbin, , China
China PLA General Hospital, Haidian Districk, Beijing, , China
Sir Run Run Shaw Hospital, Hangzhou, Zhejiang, , China
Zhejiang Cancer Hospital, Hangzhou, Zhejiang, , China
The First Affiliated Hospital of Anhui Medical University, Hefei, , China
Yunan Tumor Hospital, Kunming, , China
The First Affiliated Hospital of Nanchang University, Nanchang, , China
Jiangsu Cancer Hospital, Nanjing, Jiangsu, , China
PLA 81 Hospital, Nanjing, , China
Fundan University Cancer Hospital, Shanghai, , China
Shangahi Pulmonary Hosptial, Shanghai, , China
Shanghai Chest Hospital, Shanghai, , China
Shanghai Chest Hosptial, Shanghai, , China
Cancer Hospital of Shantou University Medical College, Shantou, , China
Tongji Hospital of Tongji Medical Colleague of Huazhong University of Science and Technology, Wuhan, , China
Peking Union Medical College Hospital, XiCheng District, Beijing, , China
Subei People's Hospital, Yangzhou, , China
Queen Elizabeth Hospital, Kowloon, , Hong Kong
Tuen Mun Hospital, New Territories, , Hong Kong
Queen Mary Hospital, Pok Fu Lam, , Hong Kong
Prince of Wales Hospital, Shatin, N.T., , Hong Kong
Samsung Medical Center, Seoul, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Yonsi University College of Medicine, Seoul, , Korea, Republic of
St. Mary's Hospital, The Catholic University of Korea, Seoul, , Korea, Republic of
National University Hospital, Singapore, , Singapore
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City, , Taiwan
Chang Gung Medical Foundation, Kaohsiung, Kaohsiung County, , Taiwan
China Medical University Hospital, Taichung City, , Taiwan
Taichung Veterans General Hospital, Taichung, , Taiwan
Chi Mei Hospital, Liouying, Tainan County, , Taiwan
National Cheng Kung University Hospital, Tainan, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Dept of Chest, Taipei, , Taiwan
Chang Gung medical Foundation, Linkou Branch, Tao-Yuan, , Taiwan
Name: Medical responsible
Affiliation: Merck Serono (Beijing), Pharmaceutical R&D Co., Ltd., an Affiliate of Merck KGaA Darmstadt, Germany
Role: STUDY_DIRECTOR