Spots Global Cancer Trial Database for A Study of Nivolumab + Chemotherapy or Nivolumab + Ipilimumab Versus Chemotherapy in Non-Small Cell Lung Cancer (NSCLC) Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor (TKI) Therapy
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Trial Identification
Brief Title: A Study of Nivolumab + Chemotherapy or Nivolumab + Ipilimumab Versus Chemotherapy in Non-Small Cell Lung Cancer (NSCLC) Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor (TKI) Therapy
Official Title: Open-Label, Randomized Trial of Nivolumab (BMS-936558) Plus Pemetrexed/Platinum or Nivolumab Plus Ipilimumab (BMS-734016) vs Pemetrexed Plus Platinum in Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC) Subjects With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor Therapy
Study ID: NCT02864251
Conditions
Study Description
Brief Summary: The main purpose of this study is to determine whether nivolumab + chemotherapy is effective as compared to chemotherapy in the treatment of patients with EGFR mutation, NSCLC who failed first line (1L) or second-line (2L) EGFR TKI therapy.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Pacific Shores Medical Group, Long Beach, California, United States
Local Institution - 0029, Los Angeles, California, United States
Local Institution - 0033, Los Angeles, California, United States
Local Institution - 0061, Orange, California, United States
Torrance Memorial Physican Network, Redondo Beach, California, United States
Local Institution - 0003, New Haven, Connecticut, United States
Local Institution - 0004, Chicago, Illinois, United States
Johns Hopkins University, Baltimore, Maryland, United States
Local Institution - 0002, Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Dana Farber Cancer Institute, Boston, Massachusetts, United States
Local Institution - 0064, New York, New York, United States
Duke University Medical Center, Butner, North Carolina, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Texas Health Physicians Group, Arlington, Texas, United States
Baylor Scott and White Research Institute, Temple, Texas, United States
Local Institution - 0063, Tyler, Texas, United States
Local Institution - 0001, Salt Lake City, Utah, United States
Local Institution - 0166, Edmonton, Alberta, Canada
Local Institution - 0168, Montreal, Quebec, Canada
Local Institution, Beijing, Beijing, China
Local Institution, Beijing, Beijing, China
Local Institution, Chongqing, Chongqing, China
Local Institution, Guangzhou, Guangdong, China
Local Institution, Zhengzhou, Henan, China
Local Institution, Hong Kong, Hong Kong, China
Local Institution - 0043, Changsha, Hunan, China
Local Institution, Changchun, Jilin, China
Local Institution, Changchun, Jilin, China
Local Institution, Xian, Shan3xi, China
Local Institution, Shanghai, Shanghai, China
Local Institution, Shanghai, Shanghai, China
Local Institution, Chengdu, Sichuan, China
Local Institution - 0016, Hangzhou, Zhejiang, China
Local Institution - 0017, Hangzhou, Zhejiang, China
Local Institution, Hangzhou, Zhejiang, China
Local Institution, Marseille, , France
Local Institution - 0156, Paris, , France
Local Institution, Rennes, , France
Local Institution, Toulouse cedex 9, , France
Local Institution - 0027, Hong Kong, , Hong Kong
Local Institution - 0024, Hong Kong, , Hong Kong
Local Institution, Shatin, , Hong Kong
Local Institution, Nagoya-shi, Aichi, Japan
Local Institution, Hirosaki-shi, Aomori, Japan
Local Institution, Matsuyama, Ehime, Japan
Local Institution, Iizuka, Fukuoka, Japan
Local Institution - 0059, Kurume, Fukuoka, Japan
Local Institution, Fukushima-shi, Fukushima, Japan
Local Institution, Koriyama, Fukushima, Japan
Local Institution, Fukuyama, Hiroshima, Japan
Local Institution, Hiroshima-Shi, Hiroshima, Japan
Local Institution - 0070, Sapporo, Hokkaido, Japan
Local Institution, Himeji-shi, Hyogo, Japan
Local Institution - 0097, Itami, Hyogo, Japan
Local Institution, Kobe City, Hyogo, Japan
Local Institution, Kobe, Hyogo, Japan
Local Institution, Bunkyo-ku, Kanagawa, Japan
Local Institution - 0081, Yokohama-shi, Kanagawa, Japan
Local Institution, Yokohama, Kanagawa, Japan
Local Institution, Yokohama, Kanagawa, Japan
Local Institution, Kumamoto-shi, Kumamoto, Japan
Local Institution, Natori-shi, Miyagi, Japan
Local Institution - 0077, Sendai-shi, Miyagi, Japan
Local Institution, Hirakata-shi, Osaka, Japan
Local Institution, Kishiwada shi, Osaka, Japan
Local Institution - 0058, Osakasayama, Osaka, Japan
Local Institution, Sakai, Osaka, Japan
Local Institution - 0076, Hidaka, Saitama, Japan
Local Institution, Kitaadachi-gun, Saitama, Japan
Local Institution - 0069, Chuo, Tokyo, Japan
Local Institution - 0078, Koto-ku, Tokyo, Japan
Local Institution, Ube Shi, Yamaguchi, Japan
Local Institution, Chiba, , Japan
Local Institution, Fukuoka, , Japan
Local Institution, Fukuoka, , Japan
Local Institution, Niigata, , Japan
Local Institution - 0079, Tokyo, , Japan
Local Institution, Toyama, , Japan
Local Institution, Wakayama, , Japan
Local Institution - 0038, Seoul, Seoul Teugbyeolsi, Korea, Republic of
Local Institution - 0037, Seoul, Seoul Teugbyeolsi, Korea, Republic of
Local Institution - 0035, Seoul, Seoul Teugbyeolsi, Korea, Republic of
Local Institution, Cheogju-si, , Korea, Republic of
Local Institution, Gyeonggi-do,, , Korea, Republic of
Local Institution - 0036, Gyeonggi-do, , Korea, Republic of
Local Institution, Inchoen, , Korea, Republic of
Local Institution, Seoul, , Korea, Republic of
Local Institution - 0042, Singapore, , Singapore
Local Institution - 0041, Singapore, , Singapore
Local Institution - 0158, Barcelona, , Spain
Local Institution, Hospitalet de Llobregat, , Spain
Local Institution, Madrid, , Spain
Local Institution, Majadahonda, , Spain
Local Institution, Malaga, , Spain
Local Institution, Zaragoza, , Spain
Local Institution - 0021, Tainan, TNN, Taiwan
Local Institution - 0045, Chiayi, , Taiwan
Local Institution, Kaohsiung City, , Taiwan
Local Institution, Kaohsiung city, , Taiwan
Local Institution - 0019, Kaohsiung, , Taiwan
Local Institution - 0018, Taichung, , Taiwan
Local Institution, Taichung, , Taiwan
Local Institution, Tainan, , Taiwan
Local Institution, Taipei City, , Taiwan
Local Institution, Taipei, , Taiwan
Local Institution - 0066, Taipei, , Taiwan
Local Institution - 0108, Taipei, , Taiwan
Local Institution - 0023, Taipei, , Taiwan
Local Institution, Taoyuan, , Taiwan
Contact Details
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR
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