Spots Global Cancer Trial Database for Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLC
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Trial Identification
Brief Title: Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLC
Official Title: A Randomized, Placebo-controlled, Double-blind, Multicenter Phase 2 Study With a Lead in Phase of Erlotinib With or Without SNDX-275 in Patients With NSCLC After Failure In Up to Two Prior Chemotherapeutic Regimens for Advanced Disease
Study ID: NCT00602030
Study Description
Brief Summary: The purpose of this study is to evaluate the safety and efficacy of entinostat in combination with erlotinib in the treatment of Advanced Non-Small Cell Lung Cancer (NSCLC).
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
HOPE (Hematology Oncology Physicians & Extenders), Tucson, Arizona, United States
Rocky Mountain Cancer Center, Denver, Colorado, United States
Advanced Medical Specialties, Miami, Florida, United States
Ocala Oncology Center, Ocala, Florida, United States
Cancer Centers of Florida, Ocoee, Florida, United States
Hematology Oncology Associates of Illinois, Chicago, Illinois, United States
Central Indiana Cancer Centers, Indianapolis, Indiana, United States
Kansas City Cancer Centers, Overland Park, Kansas, United States
Alliance Hematology Oncology, Westminster, Maryland, United States
St Joseph Oncology, Saint Joseph, Missouri, United States
The Center for Cancer Care & Research, Saint Louis, Missouri, United States
Mahonig Valley Hematology Oncology Associates, Boardman, Ohio, United States
Dayton Oncology & Hematology, Kettering, Ohio, United States
Oncology Associates of Oregon, Eugene, Oregon, United States
Texas Oncology, Amarillo, Texas, United States
Texas Oncology, Austin, Texas, United States
Texas Oncology, Bedford, Texas, United States
Texas Oncology, Sammons Cancer Center, Dallas, Texas, United States
Texas Oncology, Dallas, Texas, United States
Texas Oncology, Fort Worth, Texas, United States
Texas Oncology, Garland, Texas, United States
Texas Oncology, Longview, Texas, United States
Texas Oncology, Midland, Texas, United States
Texas Oncology, Odessa, Texas, United States
Texas Oncology, Tyler, Texas, United States
Fairfax Northern Virginia Hematology-Oncology, Fairfax, Virginia, United States
Virginia Oncology Associates, Norfolk, Virginia, United States
Highline Medical Oncology, Burien, Washington, United States
Cancer Care Northwest, Spokane, Washington, United States
Yakima Valley Memorial Hospital/North Star Lodge, Yakima, Washington, United States
Contact Details
Name: Samir Witta, MD
Affiliation: Rocky Mountain Cancer Centers
Role: PRINCIPAL_INVESTIGATOR
Name: Kartik Konduri, MD
Affiliation: Texas Oncology - Sammons Cancer Center
Role: PRINCIPAL_INVESTIGATOR
Name: Robert Raju, MD
Affiliation: Dayton Oncology
Role: PRINCIPAL_INVESTIGATOR
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