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Spots Global Cancer Trial Database for Concordance of Key Actionable Genomic Alterations as Assessed in Tumor Tissue and Plasma in Non Small Cell Lung Cancer

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Trial Identification

Brief Title: Concordance of Key Actionable Genomic Alterations as Assessed in Tumor Tissue and Plasma in Non Small Cell Lung Cancer

Official Title: A Study to Determine the Concordance of Key Actionable Genomic Alterations as Assessed in Tumor Tissue and Plasma From Patients With Non Small Cell Lung Carcinoma (NSCLC)

Study ID: NCT02762877

Interventions

Study Description

Brief Summary: A study to determine the concordance of key actionable genomic alterations as assessed in tumor tissue and plasma from patients with non small cell lung carcinoma (NSCLC)

Detailed Description: This is a prospective clinical study to characterize the concordance of key clinically relevant genomic alterations in tumor tissue (biopsy/excision/cytology) and liquid biopsy (blood) using the Genomic Health LBMP in patients with stage IV non squamous NSCLC, that are either newly diagnosed with metastatic disease or progressing on therapy (any line). Tissue biopsy and blood collection (liquid biopsy) should be less than eight weeks apart and with no new systemic antitumoral treatment given in the interval between the tissue biopsy and blood collection. Local assessment of tumor tissue samples will be performed at each participating institution as per their clinical standard of care practices and results from the local assessment of genomic alteration status will be used.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Cancer Care Associates d/b/a Torrance Memorial Physician Network, Torrance, California, United States

Central Georgia Cancer Care, Macon, Georgia, United States

Virginia Piper Cancer Institute, Minneapolis, Minnesota, United States

Essex Oncology of North Jersey, Belleville, New Jersey, United States

Meridian Hospitals, Neptune, New Jersey, United States

Gabrail Cancer Center, Canton, Ohio, United States

West Clinic, Germantown, Tennessee, United States

Bon Secours Cancer Institute, Midlothian, Virginia, United States

MultiCare Health System, Tacoma, Washington, United States

Instituto Nacional del Torax, Santiago, , Chile

Fundaci贸n Arturo L贸pez Perez, Santiago, , Chile

Clinica Alemana de Santiago, Santiago, , Chile

Centre Jean Perrin, Clermont-Ferrand, Cedex 1, France

H么pital Nord, Marseille, Cedex 20, France

Polyclinique Bordeaux Nord Aquitaine, Bordeaux, , France

St. Vincent's University Hospital, Dublin, Elm Park, Ireland

Tokyo Medical University Hospital, Tokyo, Shinjuku-ku, Japan

National Cancer Center, Tokyo, Tsukiji, Chuo-ku, Japan

Hospital Universitario Central Asturias, Oviedo, , Spain

Hospital Universitario Virgen del Rocio, Sevilla, , Spain

Hospital Clinico Universitario Lozano Blesa, Zaragosa, , Spain

Clatterbridge Cancer Center NHS Foundation Trust, Bebington, Wirral, United Kingdom

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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