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Brief Title: A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Official Title: A Randomized, Double-blind Study of the Effect of Avastin Plus Cisplatin and Gemcitabine or Placebo Plus Cisplatin and Gemcitabine on Progression-free Survival in Treatment-naïve Patients With Advanced or Recurrent Non-squamous NSCLC
Study ID: NCT00806923
Brief Summary: This 3 arm study will evaluate the efficacy and safety of adding Avastin versus placebo to a standard chemotherapeutic regimen in patients with advanced or recurrent non-squamous non-small cell lung cancer (NSCLC) who have not received prior chemotherapy. The anticipated time of study treatment is until disease progression, and the target sample size is 500+ individuals.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Bahia Blanca, , Argentina
, Buenos Aires, , Argentina
, Buenos Aires, , Argentina
, Mendoza, , Argentina
, San Miguel de Tucuman, , Argentina
, Santa Fe, , Argentina
, Santa Fe, , Argentina
, Adelaide, , Australia
, Adelaide, , Australia
, Brisbane, , Australia
, Canberra, , Australia
, Kurralta Park, , Australia
, Melbourne, , Australia
, Parkville, , Australia
, Perth, , Australia
, Sydney, , Australia
, Sydney, , Australia
, Tugun, , Australia
, Wollongong, , Australia
, Bruxelles, , Belgium
, Haine-saint-paul, , Belgium
, Leuven, , Belgium
, Liege, , Belgium
, Belo Horizonte, , Brazil
, Porto Alegre, , Brazil
, Rio de Janeiro, , Brazil
, Sao Paulo, , Brazil
, Plovdiv, , Bulgaria
, Sofia, , Bulgaria
, Sofia, , Bulgaria
, Stara Zagora, , Bulgaria
, Varna, , Bulgaria
, Veliko Tarnovo, , Bulgaria
, Calgary, Alberta, Canada
, Edmonton, Alberta, Canada
, Victoria, British Columbia, Canada
, Moncton, New Brunswick, Canada
, London, Ontario, Canada
, Mississauga, Ontario, Canada
, Newmarket, Ontario, Canada
, Toronto, Ontario, Canada
, Toronto, Ontario, Canada
, Toronto, Ontario, Canada
, Greenfield Park, Quebec, Canada
, Montreal, Quebec, Canada
, Montréal, Quebec, Canada
, Sainte-foy, Quebec, Canada
, Ostrava, , Czech Republic
, Ostrava, , Czech Republic
, Praha, , Czech Republic
, Usti Nad Labem, , Czech Republic
, Belfort, , France
, Bobigny, , France
, Caen, , France
, Lyon, , France
, Marseille, , France
, Montbeliard, , France
, Montpellier, , France
, Pierre Benite, , France
, Rennes, , France
, Rouen, , France
, St Herblain, , France
, Strasbourg, , France
, Vandoeuvre Les Nancy, , France
, Berlin, , Germany
, Essen, , Germany
, Gauting, , Germany
, Göttingen, , Germany
, Hamburg, , Germany
, Hamburg, , Germany
, Hamburg, , Germany
, Heidelberg, , Germany
, Hemer, , Germany
, Karlsruhe, , Germany
, Leverkusen, , Germany
, Mainz, , Germany
, Mannheim, , Germany
, München, , Germany
, Alexandroupolis, , Greece
, Athens, , Greece
, Athens, , Greece
, Thessaloniki, , Greece
, Hong Kong, , Hong Kong
, Hong Kong, , Hong Kong
, Budapest, , Hungary
, Mosdos, , Hungary
, Nyiregyhaza, , Hungary
, Szekesfehervar, , Hungary
, Szombathely, , Hungary
, Zalaegerszeg, , Hungary
, Jerusalem, , Israel
, Kfar Saba, , Israel
, Petach Tikva, , Israel
, Ramat-gan, , Israel
, Tel Aviv, , Israel
, Candiolo, , Italy
, Catania, , Italy
, Genova, , Italy
, Milano, , Italy
, Milano, , Italy
, Napoli, , Italy
, Parma, , Italy
, Perugia, , Italy
, Reggio Emilia, , Italy
, Roma, , Italy
, Roma, , Italy
, Rozzano, , Italy
, Gdansk, , Poland
, Gdynia, , Poland
, Lublin, , Poland
, Olsztyn, , Poland
, Poznan, , Poland
, Szczecin, , Poland
, Warszawa, , Poland
, Balashikha, , Russian Federation
, Moscow, , Russian Federation
, Moscow, , Russian Federation
, Moscow, , Russian Federation
, Moscow, , Russian Federation
, Moscow, , Russian Federation
, St Petersburg, , Russian Federation
, St Petersburg, , Russian Federation
, St Petersburg, , Russian Federation
, Alicante, , Spain
, Barakaldo, , Spain
, Barcelona, , Spain
, Barcelona, , Spain
, Barcelona, , Spain
, Girona, , Spain
, La Laguna, , Spain
, Madrid, , Spain
, Madrid, , Spain
, Madrid, , Spain
, Madrid, , Spain
, Málaga, , Spain
, Sevilla, , Spain
, Sevilla, , Spain
, Valencia, , Spain
, Valencia, , Spain
, Valencia, , Spain
, Valencia, , Spain
, Kueishan, , Taiwan
, Taichung, , Taiwan
, Taichung, , Taiwan
, Taipei, , Taiwan
, Taipei, , Taiwan
, Bangkok, , Thailand
, Chiang Mai, , Thailand
, Guildford, , United Kingdom
, London, , United Kingdom
, Manchester, , United Kingdom
, Sheffield, , United Kingdom
, Sutton, , United Kingdom
, Yeovil, , United Kingdom
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_CHAIR