Spots Global Cancer Trial Database for Study Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin, Paclitaxel and Bevacizumab in Patients With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer Who Have Not Received Prior Chemotherapy for Advanced Disease (NILE)
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Trial Identification
Brief Title: Study Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin, Paclitaxel and Bevacizumab in Patients With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer Who Have Not Received Prior Chemotherapy for Advanced Disease (NILE)
Official Title: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin , Paclitaxel and Bevacizumab in Patients With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer Who Have Not Received Prior Chemotherapy for Advanced Disease
Study ID: NCT01366131
Conditions
Study Description
Brief Summary: This is a Phase II, multicenter, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy and safety of MEGF0444A combined with paclitaxel + carboplatin + bevacizumab therapy in patients with histologically or cytologically documented inoperable, locally advanced, metastatic (Stage IV), or recurrent non-squamous NSCLC.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
, Birmingham, Alabama, United States
, Hot Springs, Arkansas, United States
, Santa Monica, California, United States
, Orlando, Florida, United States
, Port Saint Lucie, Florida, United States
, St Petersburg, Florida, United States
, Tampa, Florida, United States
, Marietta, Georgia, United States
, Indianapolis, Indiana, United States
, Wichita, Kansas, United States
, Burnsville, Minnesota, United States
, Las Vegas, Nevada, United States
, Albany, New York, United States
, Columbus, Ohio, United States
, Portland, Oregon, United States
, Hershey, Pennsylvania, United States
, Nashville, Tennessee, United States
, Austin, Texas, United States
, Fort Worth, Texas, United States
, Vancouver, Washington, United States
, St. Leonards, New South Wales, Australia
, Herston, Queensland, Australia
, Woodville South, South Australia, Australia
, Brno, , Czech Republic
, Ostrava - Poruba, , Czech Republic
, Le Mans, , France
, Lyon, , France
, Marseille, , France
, Marseille, , France
, Paris, , France
, Saint Herblain, , France
, Toulouse, , France
, Essen, , Germany
, Gauting, , Germany
, Grosshansdorf, , Germany
, Halle, , Germany
, Budapest, , Hungary
, Budapest, , Hungary
, Szekesfehervar, , Hungary
, Tatabánya, , Hungary
, Bydgoszcz, , Poland
, Gdansk, , Poland
Contact Details
Name: Ina Rhee, M.D., Ph.D.
Affiliation: Genentech, Inc.
Role: STUDY_DIRECTOR
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