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Brief Title: Skeletal Muscle Atrophy and Dysfunction in Human Cancer
Official Title: Skeletal Muscle Atrophy and Dysfunction in Human Cancer
Study ID: NCT02949076
Brief Summary: Cancer and its treatment can have profound effects on skeletal muscle, the most well-recognized being atrophy, weakness and diminished oxidative capacity. These adaptations negatively impact quality of life, treatment decisions and survival. Despite these consequences, the factors promoting these adaptations remain poorly defined and understudied in human patients. To address this gap in knowledge, our goal in this study is to examine the role of muscle disuse as a regulator of muscle size and function in human cancer patients
Detailed Description:
Minimum Age: 50 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
University of Vermont College of Medicine, Burlington, Vermont, United States
Name: Michael J. Toth, Ph.D.
Affiliation: University of Vermont
Role: PRINCIPAL_INVESTIGATOR