Spots Global Cancer Trial Database for A Phase 1b Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Non-small Cell Lung Cancer
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Trial Identification
Brief Title: A Phase 1b Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Non-small Cell Lung Cancer
Official Title: A Phase 1b Open-label Study to Evaluate the Safety and Tolerability of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Non-small Cell Lung Cancer
Study ID: NCT02000947
Study Description
Brief Summary: The purpose of this study is to determine if MEDI4736 will be adequately tolerated in combination with tremelimumab in subjects with advanced non-small cell lung cancer (NSCLC).
Detailed Description: This is a multicenter, open-label, dose-escalation, and dose expansion study of MEDI4736 in combination with tremelimumab to evaluate the safety, tolerability, pharmacokinetic (PK), immunogenicity, and antitumor activity of MEDI4736 in combination with tremelimumab in adult subjects with advanced NSCLC.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Research Site, Birmingham, Alabama, United States
Research Site, Tucson, Arizona, United States
Research Site, Los Angeles, California, United States
Research Site, Los Angeles, California, United States
Research Site, San Francisco, California, United States
Research Site, Aurora, Colorado, United States
Research Site, New Haven, Connecticut, United States
Research Site, Newark, Delaware, United States
Research Site, Tampa, Florida, United States
Research Site, Indianapolis, Indiana, United States
Research Site, Baltimore, Maryland, United States
Research Site, Boston, Massachusetts, United States
Research Site, Boston, Massachusetts, United States
Research Site, Ann Arbor, Michigan, United States
Research Site, Detroit, Michigan, United States
Research Site, Saint Louis, Missouri, United States
Research Site, Lebanon, New Hampshire, United States
Research Site, New York, New York, United States
Research Site, New York, New York, United States
Research Site, Huntersville, North Carolina, United States
Research Site, Columbus, Ohio, United States
Research Site, Portland, Oregon, United States
Research Site, Fort Worth, Texas, United States
Research Site, Houston, Texas, United States
Research Site, Tyler, Texas, United States
Research Site, Fairfax, Virginia, United States
Research Site, Seattle, Washington, United States
Research Site, Morgantown, West Virginia, United States
Research Site, Darlinghurst, , Australia
Research Site, Gosford, , Australia
Research Site, Kogarah, , Australia
Research Site, Bruxelles, , Belgium
Research Site, Gent, , Belgium
Research Site, Liege, , Belgium
Research Site, Bordeaux Cedex, , France
Research Site, Dijon, , France
Research Site, La Tronche, , France
Research Site, Lille, , France
Research Site, Lyon, , France
Research Site, Marseille, , France
Research Site, Montpellier Cedex 5, , France
Research Site, Saint Herblain, , France
Research Site, Bologna, , Italy
Research Site, Milano, , Italy
Research Site, Rozzano, , Italy
Research Site, Saronno, , Italy
Research Site, Siena, , Italy
Research Site, Sondrio, , Italy
Research Site, Cheongju-si, , Korea, Republic of
Research Site, Incheon, , Korea, Republic of
Research Site, Seongnam-si, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Seoul, , Korea, Republic of
Research Site, Barcelona, , Spain
Research Site, Barcelona, , Spain
Research Site, Jaen, , Spain
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Malaga, , Spain
Research Site, Sevilla, , Spain
Research Site, Valencia, , Spain
Research Site, Tainan, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, London, , United Kingdom
Research Site, Manchester, , United Kingdom
Contact Details
Name: MedImmune LLC
Affiliation: MedImmune LLC
Role: STUDY_DIRECTOR
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