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Brief Title: Phase I Study of LXH254 in Patients With Advanced Solid Tumors Haboring MAPK Pathway Alterations
Official Title: A Phase I Dose Finding Study of Oral LXH254 in Adult Patients With Advanced Solid Tumors Harboring MAPK Pathway Alterations
Study ID: NCT02607813
Brief Summary: A Phase I Study of LXH254 in Patients With Advanced Solid Tumors That Harbor MAPK Pathway Alterations.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Massachusetts General Hospital MGH Cancer Center, Boston, Massachusetts, United States
Memorial Sloan Kettering Cancer Center SC - LXH254X2101, New York, New York, United States
UT M.D Anderson Cancer Center SC - LXH254X2101, Houston, Texas, United States
Novartis Investigative Site, Toronto, Ontario, Canada
Novartis Investigative Site, Paris Cedex 10, , France
Novartis Investigative Site, Toulouse, , France
Novartis Investigative Site, Heidelberg, , Germany
Novartis Investigative Site, Milano, MI, Italy
Novartis Investigative Site, Modena, MO, Italy
Novartis Investigative Site, Napoli, , Italy
Novartis Investigative Site, Chuo ku, Tokyo, Japan
Novartis Investigative Site, Seoul, , Korea, Republic of
Novartis Investigative Site, Groningen, , Netherlands
Medical Oncology, Erasmus MC, Rotterdam, , Netherlands
Novartis Investigative Site, Barcelona, Catalunya, Spain
Novartis Investigative Site, Madrid, , Spain
Novartis Investigative Site, Madrid, , Spain
Novartis Investigative Site, Zuerich, , Switzerland
Name: Novartis Pharmaceuticals
Affiliation: Novartis Pharmaceuticals
Role: STUDY_DIRECTOR