Spots Global Cancer Trial Database for IO102 With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment of Metastatic NSCLC
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Trial Identification
Brief Title: IO102 With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment of Metastatic NSCLC
Official Title: An Open-label, Randomized, Phase I/II Trial Investigating the Safety and Efficacy of IO102 in Combination With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment for Patients With Metastatic Non-Small Cell Lung Cancer
Study ID: NCT03562871
Conditions
Study Description
Brief Summary: The purpose of this study is to determine if IO102 combined with pembrolizumab with or without chemotherapy is safe tolerable and effective in the treatment of Non-small Cell Lung Carcinoma (NSCLC). The hypothesis is that IO102 will improve the objective response rate (ORR) in patients with metastatic NSCLC.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Thoraxklinik Heidelberg gGmbH, Heidelberg, Community Of Heidelberg, Germany
PIUS Hospital Oldenburg, Oldenburg, , Germany
Stichting Het Nederlands Kanker Instituut, Amsterdam, Community Of Amsterdam, Netherlands
Servicio de Oncología-El médico del Virgen de la Victoria, Málaga, Andalusia, Spain
Insituto Oncologico Dr Rosell. Hospital Universitario Quiron Dexeus, Barcelona, Catalonia, Spain
Hospital Universitario de Vall d'Hebron, Barcelona, Catalonia, Spain
Hospital Universitari de Girona Doctor Josep Trueta, Girona, Catalonia, Spain
Hospital Universitario 12 Octubre, Madrid, Community Of Madrid, Spain
Hospital Universitario HM Sanchinarro, Madrid, Community Of Madrid, Spain
Hospital Universitario Ramón y Cajal, Madrid, Community Of Madrid, Spain
Hospital Puerta del Hierro Majadahonda, Madrid, Community Of Madrid, Spain
Hospital Clinico Universitario de València, València, Horta De València, Spain
Guy's Hospital, London, , United Kingdom
Contact Details
Name: James Spicer, MD Prof
Affiliation: Guy's Hospital
Role: PRINCIPAL_INVESTIGATOR
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