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Spots Global Cancer Trial Database for Effect of Lap-Band Induced Weight Loss on Serum PSA Levels

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Trial Identification

Brief Title: Effect of Lap-Band Induced Weight Loss on Serum PSA Levels

Official Title: Effect of Lap-Band Induced Weight Loss on Serum PSA Levels, Testosterone, Estrogen and Other Serum Markers

Study ID: NCT00562341

Interventions

Bariatric Surgery

Study Description

Brief Summary: The proposed prospective study aims to determine whether interpretation of PSA levels in morbidly obese men require correction due to the obesity itself. If PSA levels are found to rise after weight loss, interpretation of PSA levels in morbidly obese men may be improved by upward correction of the PSA level. A 'correction factor' may be proposed for the interpretation of PSA levels in obese men, toward the clinical decision regarding indication for prostate biopsy.

Detailed Description: The main objective of this study is to determine whether interpretation of PSA levels in morbidly obese men require correction due to the obesity itself. Secondary outcome measures that will be followed include the affect of obesity and weight loss on testosterone, estradiol and leptin. In as much as these might also affect PSA, we will be measuring these values as well. Also, we do not know the effects of lap-band induced weight loss on clinical outcome measures of sexual, bowel and urinary function. Thus we will aim to investigate these parameters as well.

Eligibility

Minimum Age: 20 Years

Eligible Ages: ADULT

Sex: MALE

Healthy Volunteers: No

Locations

Maimonides Medical Center, Brooklyn, New York, United States

Contact Details

Name: Jason Wynberg, MD

Affiliation: MMC

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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