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Brief Title: Profiling Microbiome Associated Metabolic Pathways in Oesophageal Cancer Survivors
Official Title: Profiling Microbiome Associated Metabolic Pathways in Oesophageal Cancer Survivors
Study ID: NCT06302660
Brief Summary: The goal of this observational study is to learn about long term symptoms in oesophageal cancer survivors. The main question it aims to answer is are: * Study the changes in gut bacteria by examining saliva, stool and blood. * Investigate the products of bacteria in breath to develop a non-invasive breath test to detect the changes in gut bacteria. * Develop new strategies to treat this change and trial new treatments to improve quality- of-life in oesophageal cancer survivors. Participants will attend an outpatient clinic, fasted for at least 4 hours for collection of breath, saliva, blood, urine, stool and complete validated healthy-related quality-of-life questionnaires. Researchers will compare symptomatic and asymptomatic participants to detect the changes stated above.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Barking, Havering and Redbridge University Hospitals NHS Trust, London, , United Kingdom
Imperial College Healthcare NHS Trust, London, , United Kingdom
West Hertfordshire NHS Teaching Hospitals, London, , United Kingdom